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antonis02.bsky.social
Professor of Cancer Risk Prediction Director, Cancer Data-Driven Detection University of Cambridge Genetic epidemiology, Data Science, Cancer prevention and early detection
9 posts 336 followers 300 following
Prolific Poster

📣CanRisk v.3 for breast and ovarian cancer risk prediction released today www.canrisk.org Includes 1️⃣ Adaptations to the U.K. ethnically diverse population: Pre-print: doi.org/10.1101/2025... 2️⃣ Continuous measures of mammographic density: Pre-print: doi.org/10.1101/2025...

Genetics, primary care records and lifestyle factors for short-term dynamic risk prediction of colorectal cancer bmjoncology.bmj.com/content/4/1/... Wonderful stuff from Samantha Ip, @antonis02.bsky.social , Angela Wood and co!

Read more about our recent collaborative work on multimodal dynamic risk modelling for colorectal cancer from the talented Sam Ip and Hannah Harrison. 👇

📣Vacancy alert!!! You'll need significant planning and organisational skills to coordinate and monitor across complex projects with multiple institutions (including us). 👉Cancer Data-Drive Detection (CD3) programme is a major new national research initiative. www.jobs.cam.ac.uk/job/50376/

Hello BlueSky colleagues – this is the new official account of the Centre for Cancer Genetic Epidemiology! Please follow us for updates and news related to our research.

📣 Exciting new opportunity to join the Cancer Data-Driven Detection (CD3) program as Senior Research Programme Manager based at @dphpc.bsky.social @cambridgeuni.bsky.social Closing date 16 March 2025 Please repost! More about CD3 below. 👇 www.jobs.cam.ac.uk/job/50376/

This interesting study linked germline testing and EHR/registry data from the UK NHS to characterize the risk of 2nd primary cancers for pts w/ pathogenic variants in BRCA1/BRCA2. 10-yr cumulative risk of contralateral BC was 16% in BRCA1+ and 12% in BRCA2+ ascopubs.org/doi/10.1200/...

Through linking test results to electronic health records in England from 1995-2019, researchers estimated relative & absolute second primary #cancer risks for #BRCA carriers after #breastcancer. Read the full article to learn more: ascopubs.org/doi/10.1200/... @tpalmd.bsky.social

📣📣Genomic data sharing: you don’t know what you’ve got (till it’s gone) www.nature.com/articles/s41... A comment @natrevgenet.bsky.social from @katholt.bsky.social and me

Hello BlueSky community, and welcome to our official account! 🎉 Follow us for the latest updates, events, and news. Stay connected and engage with our community!

This is a very sad day. It diminishes the USA; it will drive people into poverty and it will lead to many needless deaths

Happy PM day to all who celebrate! PubMed, that is. BMJ Oncology is proud to announce that all our content is now available on PubMed! 🎉 🍾 🥂 @journal-kristoffer.bsky.social @mazer.us @eabhalynn.bsky.social @oncoalert.bsky.social

🚨🌱 Interested in making scientific computing greener? Here is a chance to do just that in Cambridge: 2 open research roles to work with me and the Green Algorithms project. More details about the roles below👇 and at www.lannelongue-group.org/join/ ⏳ Closing: Feb 4 for one, Feb 17 for the other

There is a full weekend ahead to look into our open Postdoc position. If you'd like to study breast cancer tissue architecture with cutting-edge imaging data and novel computational methods, please apply! The deadline to apply is next Wednesday, the 29th 😉

A huge thank you to our funders for making this possible! It’s been truly inspiring to work alongside an extraordinary community of co-investigators & patient and public partners, in developing the proposals. Deeply grateful for the constant support from the central CRUK team throughout the process.

This Medical News article discusses the ongoing debate about whether the word #cancer should be dropped from the names of indolent tumors of the prostate and breast. #MedSky #OncSky

Many, many, many things have been tried in trying to improve access to general practice. @thisinstitute.bsky.social and @healthfoundation.bsky.social have curated those efforts: bjgpopen.org/content/earl...

Looking for a PhD studentship to commence October 2025?   The Early Cancer Institute invites applications from UK students for two 3.5 year fully funded non-clinical studentships.  Application deadline: 16 February 2025 Find out more ➡️ zurl.co/1HyFJ

Excited to share our latest study in @nature.com We used a humanized-mouse ES cell model to explore the functional consequences of all possible BRCA2 missense variants. We've clinically classified >6,500 variants and >1,200 reported in ClinVar! www.nature.com/articles/s41...

The latest publication from the group, led by talented early career researchers Carmen Petitjean and Xin Yang @xinyang6699.bsky.social on the performance of BOADICEA/CanRisk for breast cancer risk prediction in UKBiobank out now in JNCI. Paper: doi.org/10.1093/jnci... 🧵👇

Looking forward to speaking in this session today at #SABCS24 @sabcs.bsky.social on the latest work on CanRisk tools (www.canrisk.org) for breast cancer risk prediction, including adaptations to ethnically diverse populations. @crukcamcentre.bsky.social

NEW PAPER A scoping review of updating methods in AI/ML based prediction models doi.org/10.1016/j.jc... w/ @lottameijerink.bsky.social and others

Dr. Judy Garber shared the OlympiA Phase 3 trial results in today's #SABCS24 General Session. #olaparib #BRCA1 #BRCA2 #BreastCancer

Have you ever wondered how knocking out every single gene in the human genome, one by one, might affect your intracellular pathogen of interest? We did, & boy was it a wild ride! Happy to share our preprint discovering the essential host genome for Cryptosporidium - www.biorxiv.org/content/10.1...

Long awaited peer review finally completed!! Our paper comparing quantitative metabolomics disease risk prediction with PGS is accepted in Nature Comms!! 🥳🥳 @nightingalehealth.com #riskprediction #metabolomics #nmr #genomics #polygenicscore www.nature.com/articles/s41...

Looking for collaborators to work on federated Real World Evidence studies related to cancer. We are building our infrastructure and need high value demonstaror projects. #OHDSI #EHDEN #OMOP #RWE please get in touch

If you're interested in the PGS Catalog Calculator we're hosting a free training webinar @ebi.embl.org on December 4th: www.ebi.ac.uk/training/eve... (registration required). Come along, or catch up with the recording after! cc @iamslambert.bsky.social

📢 Don’t miss our next Cancer Biology and Medicine talk tomorrow! DNA Repair Prof Steve Jackson @cruk-ci.bsky.social Thurs 28 Nov, 9:30-10:30 Theo Chalmers lecture theatre, School of Clinical Medicine All welcome! @cuhnhs.bsky.social @cambridgeuni.bsky.social

Hi BlueSky 👋😀 This is the new official BlueSky account for the MRC Biostatistics Unit. Follow us for research, news and events on all things biostatistics and data science.

For parents who may be scared or vaccine hesitant, my go-to resource to direct them for further reading is the Oxford Vaccine Knowedge project It is an invaluable, comprehensive source of trustworthy information for families I highly recommend it #MedSky #IDSky #PedSky 🧪

Welcome to the Cancer Research UK Cambridge Centre on BlueSky! 🌟 We're a team of 1200+ experts tackling cancer from all angles. Partnering with @cancerresearchuk.bsky.social, @cambridgeuni.bsky.social & Cambridge University Hospitals. Follow for cutting-edge research. #TogetherWeAreBeatingCancer

Putting together a starter pack for people working in genetics and healthcare. Please let me know if you want to be added. go.bsky.app/FpcXQK7

Since I've been here for a while… here are some useful features on Bluesky that you might not have discovered yet! 🧵

Great to see this R package: stephenrho.github.io/pminternal/ Implements the (in)stability plots and checks recommended by myself & @gscollins.bsky.social after developing a prediction model Our paper is here: onlinelibrary.wiley.com/doi/full/10....

We're new here! If you are too, you might like to take a look at our website to find out more about who we are and what we do: www.cruk.cam.ac.uk

⏳ Just one more week to apply! 5 roles open in my group working on the Green Algorithms project: 3 research, a Software Engineer Lead and a Community manager/project coordinator 🌱 More details and links to all adverts there: www.green-algorithms.org/join-us/ Closing 25/11 #AcademicSky #SciSky

It’s fantastic to find so many friends already here. As others have noted, this feels like the early days of science twitter (RIP).