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arielkaplan.bsky.social
Single molecule biophysics, Optical Tweezers, Chromatin, Transcription, Polymerases, Helicases Associate Professor, Technion-Israel Institute of Technology https://kaplan.net.technion.ac.il/
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Wow - this is also the cofactor for the lyase activity of Cyp17A1 - required for production of androgens from pregnenolone/progesterone.

www.cell.com/molecular-ce...

Congratulations to Prof. Nabieh Ayoub on receiving the Award for Outstanding Excellence in Teaching for the Spring Semester of 2024 biology.technion.ac.il/en/congratul...

Did you know that there is an enzyme called ATAC, which is not related to ATAC-seq? :) academic.oup.com/nar/advance-... This paper reports a very interesting finding that ATAC and SAGA increase TF binding to DNA target sites on nucleosome by an order of magnitude independent of histone acetylation

Scientists, academics, researchers: We’re excited to share that @altmetric.com is now tracking mentions of your research on Bluesky! 🧪

Best practice mass photometry: A guide to optimal single molecule mass measurement https://www.biorxiv.org/content/10.1101/2024.12.03.624087v1

As you make have seen, there is a special issue of JMB on "Controlling Transcription Elongation and Termination: More Than a Means to An End" curated by my colleague here at Pitt Karen Arndt and by Steve Buratowski from Harvard Medical School 🧪🧵 1/ www.sciencedirect.com/science/arti...

Single-molecule states link transcription factor binding to gene expression www.nature.com/articles/s41...

"Dark TFs": new manuscript mapped 166 uncharacterized human transcription factors, finding half bind genomic "dark matter," often closed chromatin rich in transposable elements. www.biorxiv.org/content/10.1...

Welcome Oded! @bejalab.bsky.social

Genome access is transcription factor-specific and defined by nucleosome position https://www.sciencedirect.com/science/article/pii/S1097276524006634

Regulation of transcription by condensates, great review by @bsabari.bsky.social and coll. www.nature.com/articles/s41...

So, here I am. The nucleosome police now flies under their official tag. Please follow me if you are interested in #chromatin, #nucleosome, #cryoEM, #scienceeducation, #hiking, #quilting, and #nature. Help me figure out this platform!