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axonsalex.bsky.social
Developmental Neurobiologist at UZH | Microscopy Enthusiast. Using the chicken embryo to decipher the molecular mechanisms of neural circuit formation. Fascinated by axonal growth cones, primary cilia, and extracellular vesicles.
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Please welcome our official #mesoSPIM channel on this platform, @mesospim.bsky.social. Repost is appreciated!

Pure axonal Mayhem for this #FluorescenceFriday! growth, turn, collapse, stalling, retraction fibers...🧐⁉️ #Neuroscience #CellBiology #LiveImaging 🧪

A brief history of The Company of Biologists - 100 years of supporting scientists!👍👏 journals.biologists.com/jcs/article/...

Join us in beautiful Quintay to celebrate 25 years of the Practical Course on Developmental Biology! To register go to biodesarrollo.unab.cl/mini-symposi... Come to enjoy a unique blend of science, sea, and food – all for free!

Did you know 2024 was our 20th anniversary? We're closing it out by sharing a brief history of Addgene, with commentary from our incredible community. Read it below! blog.addgene.org/add...

2024 #FluorescenceFriday retrospective: It was a great year in science for microglia, the brain's immune cells! The brain is much more than neurons; these little cells are essential, particularly in inflammatory processes. Check them interacting below! Markers: neurons (🔵 MAP2), microglia (🟡 IBA1)

How proximal is proximity labeling❓ Using DNA nanorulers we found that TurboID/BioID are largely contact labeling, while APEX2 also bears a major contact labeling pathway in parallel with diffusive labeling. www.biorxiv.org/content/10.1... Special thanks to @aliceyting.bsky.social for discussions

I am super excited to share our article addressing a longstanding question in neurobiology: how Ca²⁺ signaling cascades initiated at dendritic spines operate at a distance. Check it out here: authors.elsevier.com/sd/article/S... @cp-cell.bsky.social.

For this #FluorescenceFriday, let's watch an axonal growth cone (for a change) displaying its most beautiful filopodia (this time)! 🤩 They are so dynamic! 1 image taken every 500 ms for 5 min played at 15 fps. 🧪

I used VVD Viewer for this #FluorescenceFriday video: 141 volumes from the #HHMIJanelia FlyLight Split-GAL4 #Drosophila driver collection. The animation comes from a high-level description processed by neuVid. Such a rapid tour of the data has questionable scientific value, but it's fun to watch!

Vimentin-mSG FRAP

Lynn Landmesser was a giant in the field of developmental neurobiology. Sad to hear of her passing. #DevBio #neuroscience 🧪

This axonal growth cone from a culture of spinal neurons decided to display its most beautiful lamellipodia for this #FluorescenceFriday! 🤩 #neuroscience #liveimaging 🧪 1 image taken every second for 10 min, played at 15 images/s

Excellent preprint from @goodfrognosis.bsky.social’s lab, showing convergence of #autism related proteins at the #cilium (sure to interest people working on cilia/centrosome on this platform; ping @cilialab.bsky.social) www.biorxiv.org/content/10.1...

Come to be our colleague @pasteur.fr! center of Paris, great colleagues, outstanding facilities, permanent position, crème brûlée every Friday - what else could one want?

Viral tracing (yellow) in the mouse adult spinal cord (cyan, nuclei; magenta, axons). Image by the very talented Soizic Riche. #fluorescencefriday #fluorescentfriday

It’s time for another #FluorescenceFriday! 👩‍🎨🎨🔬🫀multi-color labeled zebrafish heart with mosaic expression of diverse myl7:color plasmids 🏳️‍🌈🌈

New @dev-journal.bsky.social editorial We know we have high standards - but we're committed to making publishing with us constructive From clear revision guidance to limitations sections & transparent peer review, we're here to help you share your science journals.biologists.com/dev/article/...

This cell's actin cytoskeleton is one of my favorite! #FluorescenceFriday

🚀 It's #FluorescenceFriday, and commissural axons are coming at you! 🧪🔬 15-hour time-lapse of chick commissural axons navigating and crossing the CNS midline (and reverse). One stack taken every 10 minutes. Pixels were color-coded in the z-axis. #LiveImaging #Neuroscience #Science #Microscopy 🧠✨

Successful transplant of hiPS-cell derived corneal epithelium in @thelancet.bsky.social

We are happy to report that our journals and community sites now have Bluesky accounts. Follow them at: @dev-journal.bsky.social @jcellsci.bsky.social @jexpbiol.bsky.social @dmmjournal.bsky.social @biologyopen.bsky.social @the-node.bsky.social @prelights.bsky.social @focalplane.bsky.social

Starting the week strong! Cheering myself up for the next challenges with 15 min of axonal growth cone dynamic madness. F-actin (cyan) and membrane (magenta) show their dance. One image taken every 10 s.🧠🔬 #MicroscopyMonday #LiveImaging #Neuroscience #Microscopy

Leave me alone it's #Fluorescencefriday !➡️ two axonal growth cones growing together until one got fed up of the other... #neuroscience #microscopy #liveimaging

I thought #fluorescencefriday would be a good opportunity for my first post here. Here are some crazy actin dynamics imaged with TIRF

Happy #FluorescenceFriday ! Let's celebrate with a colorful image of a developing ventral spinal cord of a 🐣 embryo. #neuroscience #microscopy

A little #neuralcrest for #FluorescenceFriday #DevBio

A 🦋-inspired neural tube for #FluorescenceFriday! Imaged by @siewzhuan.bsky.social #DevBio 🧪👩‍🔬