aydoganlab.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

The deadline to apply for the MBL Physiology course is fast approaching, January 27th! Consider applying to this amazing, life-changing research discovery experience in Woods Hole! www.mbl.edu/education/ad...

submitted 38 days ago • 0 comments

The central clock drives metabolic rhythms in muscle stem cells www.biorxiv.org/content/10.1...

submitted 42 days ago • 0 comments

Fascinating paper! No G2/M checkpoint for under-replicated cells! academic.oup.com/nar/article/...

submitted 47 days ago • 3 comments

Self-generated gradients guide collective cell movement -but often different cell types must move together, e.g. in immune response. We develop a theory of self-generated chemotaxis in mixed populations -are there optimal principles for this cooperation?🤔 www.biorxiv.org/content/10.1...

submitted 49 days ago • 2 comments

Have you ever wanted to see receptor activity in embryos? If so, our new preprint is for you! In it, we showcase a new live-cell biosensor for visualizing receptor tyrosine kinase activity in living embryos – pYtags! www.biorxiv.org/content/10.1...

submitted 50 days ago • 3 comments

How hard do bacteria-eating nematodes bite in order to break the bacterial cell wall? Check out our new paper, led by Jason Casar & collab with Jen Dionne, using pressure sensing beads that change color upon compression (bluetorial coming soon) rdcu.be/d5n7v

submitted 56 days ago • 9 comments

Thrilled to announce that the Jao Lab is relocating to Syracuse University in Jan 2025 🐮➡️🍊. We continue to study macromolecular assembly and more. We are hiring at all levels! The first postdoc position: www.sujobopps.com/postings/107.... Come join us! #CellBiology #DevelopmentalBiology #zebrafish

submitted 91 days ago • 1 comment

Academics from poorer socio-economic backgrounds are more likely to - not publish - have outstanding publication records - introduce more novel scientific concepts - less likely to receive recognition, as measured by citations, Nobel Prize nominations, and awards. www.nber.org/papers/w33289

submitted 66 days ago • 23 comments

Mitochondria consist of networks of cylindrical tubes, right? Not necessarily! - in our new preprint, @gavsturm.bsky.social investigates how mitochondria transiently adopt a beads-on-a-string morphology www.biorxiv.org/content/10.1...

submitted 65 days ago • 6 comments

Striking biology! Makes one wonder whether this Stentor species at some point gulped its endosymbiont as a whole and somehow retained their nuclei as is? Could that possibly explain the crazy strings of semi-separate nuclei that Stentor has? Might be totally dreaming here..

submitted 67 days ago • 0 comments

Very glad to see our story on the choreography of #ESCRT proteins in #archaeal cell division finally published in mBio - Junfeng Liu et al "A relay race of ESCRT-III paralogs drives cell division in a hyperthermophilic archaeon" journals.asm.org/doi/10.1128/...

submitted 67 days ago • 0 comments

Excited to share the major work of my dissertation, out now in @currentbiology.bsky.social! We use Drosophila genetics to dissect the evolution of phage-derived toxins that were horizontally transferred to insects and now function as potent anti-parasitoid defenses (1/n): tinyurl.com/2k9ypyxr

submitted 68 days ago • 8 comments

Gordon Conferences happen because Chairs and Vice Chairs raise the money needed. The Cell Contact and Adhesion GRC has an NIH grant pending with a good score, but we also need others to step up. 1/2

submitted 70 days ago • 1 comment

🍾Our small #UExM adventure is only starting! #ProtistsOnSky We are happy to announce that the Moore Foundation will be funding our efforts in creating an Expansion Microscopy atlas of #Microbial #Eukaryotes with @gautamdey.bsky.social @UNIGE @embl.org LINK: www.unige.ch/sciences/chi... 1/4

submitted 71 days ago • 12 comments

First post on bsky. We've updated our preprint about the change in the histone H3 variant on chromatin during Zygotic Genome Activation. Thanks to new experiments by Anusha, it seems like our initial, simplistic idea that the embryo "ran out" of H3 was not right. www.biorxiv.org/content/10.1...

submitted 75 days ago • 1 comment

Our work on how cell junction-cytoskeletal linkage is regulated is out. Great work by @emily-mcparland.bsky.social, @noahgurley.bsky.social & others. Thanks to @jcellsci.bsky.social for straightforward review & for open access via a Read & Publish agreement 🧪 journals.biologists.com/jcs/article/...

submitted 74 days ago • 4 comments

#cellbio2024: sorry to miss you all this year (Final Exam & grading), but our lab will be well represented. Postdoc @maikbischoff.bsky.social will be giving a talk Monday 12/16 4:00 PM in the "Welcome to the Zellenstaat" session. He'll describe his exciting work on regulation of cell migration 1/3

submitted 75 days ago • 2 comments

In the beautiful city of San Diego for #ASCB with my PI Mustafa @aydoganlab.bsky.social! Excited (and nervous) for my presentation! #cellbio24

submitted 75 days ago • 1 comment

Now official: our next @embl.org course on #Drosophila Genetics & Genomics will be held 3-8 Aug '25. Send in your applications! @bsdb.bsky.social @gensocuk.bsky.social @flybase.bsky.social @fly-eds.bsky.social @socdevbio.bsky.social @the-node.bsky.social @virtualflybrain.bsky.social

submitted 76 days ago • 1 comment

🚨 Our latest study, "Yeast Knowledge Graphs Database for Exploring Saccharomyces cerevisiae and Schizosaccharomyces pombe," has just been deposited in @biorxivpreprint.bsky.social ! We’re thrilled to share our work with the world! #KnowledgeGraphs www.biorxiv.org/content/10.1101/2024.12.04.626523v1

submitted 79 days ago • 2 comments

Imagine seeing a disease's impact on every cell in the body. Now, you can! We introduce MouseMapper, an AI tool to reveal system-wide disease perturbations. It reveals obesity-induced changes in facial nerves & body-wide inflammation 👉🧵https://biorxiv.org/content/10.1101/2024.08.18.608300v1.full.pdf

submitted 84 days ago • 4 comments

If you like Wallace's blue-torial (what are we calling the tweetorial equivalent over here btw) and are going to ASCB, look out for my talk Tues. Dec 17th on how the microtubule cytoskeleton dictates RNA regionalization in Stentor! #cellbio2024 #stentor #protist #NIHMOSAIC

submitted 86 days ago • 1 comment

Where does pattern come from inside cells? in this revised preprint, @aralbright.bsky.social Shows that regionalization of mRNA in a Stentor cell depends on dynein motors and the microtubule cytoskeleton doi.org/10.1101/2023...

submitted 86 days ago • 3 comments

Our paper is out just in time for #EM_Monday! It is about a specialized neuron-specific ER, called the spine apparatus, which is found close to synapses and has a very peculiar shape. If you think neurons are special, the spine apparatus is their🦄 horn! But how does it form?! doi.org/10.1016/j.cu...

submitted 86 days ago • 15 comments

Please check our latest paper on using @deep-mind.bsky.social AlphaFold 3 to study NLR immune receptors. Here we use AI-guided structural modelling to distinguish between sensor and helper NLRs! 👇🧵 (1/10) #EvoMPMI #NLRbiology #PlantPath #PlantSci doi.org/10.1101/2024...

submitted 87 days ago • 3 comments

It may be hard to grasp from outside the benefits of fruit flies as a model organism to study tissue formation and homeostasis. Check out the below thread from @peiferlabunc.bsky.social to see all the practical and conceptual aspects of why the fly and its research community are at a prime time!

submitted 87 days ago • 0 comments

#RNA enthusiasts, got a question for you.. How could one experimentally differentiate b/w a net increase in RNA synthesis vs. an issue with RNA export (like RNA getting stuck excessively in the nucleus)? Are there tips/tricks in single nucleus seq or RNA-FISH etc to be able to delineate this?

submitted 88 days ago • 5 comments

While our bodies seem static, our cells are constantly changing shape or on the move during tissue homeostasis or wound repair & even more dramatically during embryonic development, during events like gastrulation. Defining how cellular machines mediate these events is a key task for our field 1/n

submitted 89 days ago • 17 comments

Just bumping this > What do folks think of Cytoscape? Other alternatives?

submitted 91 days ago • 0 comments

#systemsbiology hive mind, what’re the best protein-protein interaction visualisation tools nowadays for depicting a network of a custom set of >50 proteins and their interactors? Talking about visualizing >500 or so proteins. Any suggestions or reference examples would be much appreciated!!

submitted 94 days ago • 0 comments

More 👇 bioicons.com scidraw.io inkscape.org biogdp.com reactome.org/icon-lib

submitted 96 days ago • 1 comment

Our paper on fluorogenic triacylglycerols as sensor molecules for lipid oxidation is now published in Analytical and Bioanalytical Chemistry!! Very pleased to see this finally out and grateful to all co-authors for making this possible! Chemsky

submitted 97 days ago • 5 comments

We’re thrilled to pre-advertise an EMBO Workshop we're organizing, featuring an incredible lineup of speakers! 🎉 Bring your unconventional models and join us in Edinburgh next June for an exciting and inspiring event. Stay tuned for our official poster and website, coming soon! 🧪

submitted 97 days ago • 1 comment

🔬 Curious about #mitochondria #imaging but unsure where to begin? Our review might help! 🚀📜🧪 www.annualreviews.org/content/jour... #Quantitative #Microscopy #SuperResolution #AcademicSky #ScienceSky #CellBiology #mtDNA

submitted 101 days ago • 7 comments

#microscopy folks! Does anyone have experience in combining fixed mitotracker dye with immunostaining of antibodies? Either in cell culture or tissue samples? Would love to hear tips and tricks! Alternatively, any rhodamine-based or organic dye fixation combined with immunostaining.

submitted 98 days ago • 0 comments

OK, this is just a damn cool article 🤯 🦠 🔬 Infecting the cell nucleus, gaining nutrients, but preventing cell death! www.nature.com/articles/s41...

submitted 99 days ago • 1 comment

In September the world lost one of the great biologists of our time: Joe Gall. He bridged the transition from the histology era of cell biology to our molecular present, contributing a remarkable set of insights in his 9 decades 1/n 🧪 rupress.org/jcb/article-...

submitted 103 days ago • 7 comments

Cell and developmental biologists--Join us at the 2025 Cell Contact and Adhesion Gordon Conference. We've assembled a strong and diverse program of speakers at the cutting-edge of science in our field 1/n Please repost www.grc.org/cell-contact...

submitted 108 days ago • 1 comment

We’re pleased to share our substantially updated (more below on that…) version of our manuscript exploring the relationship between conservation in sequence/function for intrinsically disordered regions (IDRs) www.biorxiv.org/content/10.1...

submitted 109 days ago • 6 comments