Profile avatar
bcarra.bsky.social
5 posts 319 followers 422 following
Regular Contributor
Posts 11 Comments 2

Our first deposition of synaptic vesicles segmentations is now in the Cryo ET Portal! We segmented vesicles in over 50 tomograms to enable analysis of membrane proteins and more. cryoetdataportal.czscience.com/depositions/...

submitted 7 days ago • 2 comments

Exciting update on the CryoET Data Portal! A new annotation set from Mart Last & team is now live. They’ve doubled available annotations with >1,800 tomograms of Chlamydomonas reinhardtii which now have almost fully dense labels, and all can be visualized in the browser using Neuroglancer.

submitted 36 days ago • 1 comment

As of 2021, ~530 drugs available on the market are targeted #GPCRs. About 60% of the total #GPCR complex structures solved have been resolved by #cryoEM. Cryo-EM enables visualization of GPCRs in complex with trimeric G-proteins, in a variety of conformations. 📑 Learn more: bit.ly/gpcr

submitted 88 days ago • 0 comments

For the #ML and #CryoET folks out there: Are folks on here submitting to the CZII CryoET Object Identification competition: www.kaggle.com/competitions... ? The leaderboard is really interesting, and the forums are full of insights. How many of the latest picking models have been submitted?

submitted 82 days ago • 0 comments

CZII’s cryoET particle picking machine learning challenge is up and running. More than 3400 signups on Kaggle, great discussions going on, and leaderboard scores better than we were able to do! Start off at: cryoetdataportal.czscience.com/competition

submitted 96 days ago • 1 comment

bit.ly/3T9sZ6D Built for biologists and developers, you can find and visualize datasets in the #CryoET Data Portal or download them for your work. We’re working with EMPIAR to host data and support annotation. Please share feedback and contribute datasets or annotations.

submitted 441 days ago • 0 comments

Our team at #CZImagingInstitute is excited to share the #CryoET Data Portal beta release. With over 13,000 tomograms, it’s the start of what we hope will be a large, open-access portal of high-quality, standardized & annotated cryo-ET data. bit.ly/3T9sZ6D

submitted 441 days ago • 0 comments

This was missed due to major live events happening around the same time, but we have released some of our high-resolution (2 Å) and rapid screening #cryoEM maps & models of the human CAK bound to small molecules. Paper still under review - more to follow. www.ebi.ac.uk/emdb/search/...

submitted 490 days ago • 0 comments

Meet the PyShell!🥧🐚 Diatom pyrenoids fix up to 20% of the Earth's #CO2🌏. We discovered that their Rubisco is encased in a tight protein lattice that is essential for efficient carbon fixation and cell growth🌱 Super excited to share our new preprint📜: www.biorxiv.org/content/10.1... 🌾🧪 🧶🧬 ❄️🔬

submitted 490 days ago • 5 comments

😱📣 BlueSky-ers: WE NEED YOUR HELP!!! 🙏 All of you who ever liked a lecture of mine... All of you who liked one of the courses I teach in... All of you I work(ed) with in one way or another... All of you who see my desperation! 😜 PLEASE re-post! 🙏 careers.humantechnopole.it/o/postdoc-in...

submitted 490 days ago • 2 comments

Thanks Karolin (@nucleosomepolice.bsky.social) for inviting me here. Seems like a lot of cryoEM/ET friends have joined. Is there the equivalent of #cryoem and #teamtomo?

submitted 518 days ago • 3 comments