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biorxiv-immuno.bsky.social
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The vaginal microbiota composition influences cervicovaginal and systemic inflammation induced by Chlamydia trachomatis infection. https://www.biorxiv.org/content/10.1101/2025.02.20.638673v1

submitted 12 hours ago • 0 comments

Inhibition of NLRP1 Inflammasome Activation by Tyrosine Kinase Inhibitors Restores Erythropoiesis in Diamond-Blackfan Anemia Syndrome https://www.biorxiv.org/content/10.1101/2025.02.20.639294v1

submitted 12 hours ago • 0 comments

A Metabolite-Based Resistance Mechanism Against Malaria https://www.biorxiv.org/content/10.1101/2025.02.20.639306v1

submitted 12 hours ago • 0 comments

Cytokine-Induced Transcriptional Changes in Human Neutrophils Reveal Immune Regulatory Plasticity https://www.biorxiv.org/content/10.1101/2025.02.20.639233v1

submitted 19 hours ago • 0 comments

Single-cell omics-based characterization of human basophils reveals two transcriptionally distinct populations https://www.biorxiv.org/content/10.1101/2025.02.20.639059v1

submitted 23 hours ago • 0 comments

Targeting Anti-HLA Class I and II Antibodies with CAR-B Cell Therapy: A Novel Strategy to Mitigate Graft Rejection and Platelet Refractoriness https://www.biorxiv.org/content/10.1101/2025.02.20.639042v1

submitted 23 hours ago • 0 comments

Endothelial-leukocyte interaction in CAR T cell neurotoxicity https://www.biorxiv.org/content/10.1101/2025.02.19.638920v1

submitted 1 day ago • 0 comments

Identification of novel cis-acting elements, E-box and ISRE, regulating IFNγ-IRF1 axis-mediated NLRC5 expression https://www.biorxiv.org/content/10.1101/2025.02.20.639218v1

submitted 1 day ago • 0 comments

Low Dose Methotrexate has Divergent Effects on Cycling and Resting Human Hematopoietic Stem and Progenitor Cells https://www.biorxiv.org/content/10.1101/2025.02.19.639055v1

submitted 2 days ago • 0 comments

The role of GATA2 in the expression of the soluble decoy receptor ST2/IL1RL1 in human and mouse mast cells https://www.biorxiv.org/content/10.1101/2025.02.19.638998v1

submitted 2 days ago • 0 comments

Immunological characterization of peritoneal exudate cells in liver cirrhosis patients https://www.biorxiv.org/content/10.1101/2025.02.19.638957v1

submitted 2 days ago • 0 comments

A distinctive subset of microglia positioned at the paraventricular zone are dedicated to cleaning the cerebrospinal fluid https://www.biorxiv.org/content/10.1101/2025.02.23.639717v1

submitted 2 days ago • 0 comments

Kidney cortex macrophages prevent the formation of mineral stones by reabsorbing phosphate from the urine https://www.biorxiv.org/content/10.1101/2025.02.18.638798v1

submitted 3 days ago • 0 comments

GATA2 Mediates Macrophage Proliferation During Atherosclerosis https://www.biorxiv.org/content/10.1101/2025.02.18.638845v1

submitted 3 days ago • 0 comments

The immunometabolic topography of tuberculosis granulomas governs cellular organization and bacterial control https://www.biorxiv.org/content/10.1101/2025.02.18.638923v1

submitted 3 days ago • 0 comments

HIV-1 derived replication intermediates/oligonucleotides induce a type I IFN-dependent immune suppression via STING activation that can be restored by targeting IFNARI https://www.biorxiv.org/content/10.1101/2025.02.17.638698v1

submitted 4 days ago • 0 comments

Resolution of in situ inflammation in human lupus nephritis into principal immune cell trajectories https://www.biorxiv.org/content/10.1101/2025.02.17.638655v1

submitted 5 days ago • 0 comments

JAK inhibitors remove innate immune barriers to allow viral propagation https://www.biorxiv.org/content/10.1101/2025.02.17.638720v1

submitted 5 days ago • 0 comments

A temporary challenge by tumor cells can lead to a permanent partial-impairment of memory CD8 T cell function https://www.biorxiv.org/content/10.1101/2025.02.17.638652v1

submitted 5 days ago • 0 comments

Immunological and clinical markers of post-acute sequelae of COVID-19: Insights from mild and severe cases six months post-infection https://www.biorxiv.org/content/10.1101/2025.02.18.638851v1

submitted 5 days ago • 0 comments

Characterisation of CD4 Th subsets as well as dietary, exercise and lifestyle factors in an established Rheumatoid Arthritis cohort; pilot study. https://www.biorxiv.org/content/10.1101/2025.02.16.638543v1

submitted 5 days ago • 0 comments

Themis and Grb2 form a constitutive structural hub in T cell receptor signalling https://www.biorxiv.org/content/10.1101/2025.02.16.638521v1

submitted 6 days ago • 0 comments

Wnt-Activated Immunoregulatory Myeloid Cells Prevent Relapse in Experimental Autoimmune Encephalomyelitis and Offer a Potential Therapeutic Strategy for Multiple Sclerosis https://www.biorxiv.org/content/10.1101/2025.02.16.638560v1

submitted 6 days ago • 0 comments

Early resident NK cell response to local HIV infection in lymphoid tissue https://www.biorxiv.org/content/10.1101/2025.02.17.638403v1

submitted 6 days ago • 0 comments

Development of iPSC-Derived T Cells Targeting EGFR Neoantigens in Non-Small Cell Lung Cancer https://www.biorxiv.org/content/10.1101/2025.02.15.638388v1

submitted 6 days ago • 0 comments

Immunological surveillance using gSG6-P1 biomarker reveals spatio-temporal dynamics of Anopheles exposure and gaps in malaria risk assessment https://www.biorxiv.org/content/10.1101/2025.02.15.638477v1

submitted 6 days ago • 0 comments

Developing Interferon-β as a safe in-vivo experimental-medicine model of human inflammation. https://www.biorxiv.org/content/10.1101/2025.02.18.638888v1

submitted 6 days ago • 0 comments

Likely circulation of a coronavirus in roe deer (Capreolus capreolus) populations suggested by SARS-CoV-2 serological investigation in France https://www.biorxiv.org/content/10.1101/2025.02.19.639030v1

submitted 7 days ago • 0 comments

Harnessing the immune system to treat bone loss: The immunomodulatory and osteoprotective effects of the microalga Skeletonema costatum https://www.biorxiv.org/content/10.1101/2025.02.14.638280v1

submitted 7 days ago • 0 comments

Extrafollicular activation of B cells contributes to the long-term survival of CD28KO mice infected with Sylvio X10/4Trypanosoma cruzi parasites https://www.biorxiv.org/content/10.1101/2025.02.14.638268v1

submitted 7 days ago • 0 comments

Themis dominates T cell exhaustion by regulation of TCR and PD-1 signaling https://www.biorxiv.org/content/10.1101/2025.02.17.634430v1

submitted 7 days ago • 0 comments

Microbial metabolism of food allergens determines the severity of IgE-mediated anaphylaxis https://www.biorxiv.org/content/10.1101/2025.02.17.638013v1

submitted 7 days ago • 0 comments

Neutralizing antibodies elicited by Nipah virus G-head nanoparticle target diverse sites and inhibit receptor binding and fusion https://www.biorxiv.org/content/10.1101/2025.02.16.638571v1

submitted 7 days ago • 0 comments

NK cell-macrophage interactions in granulomas correlate with limited tuberculosis pathology https://www.biorxiv.org/content/10.1101/2025.02.14.638234v1

submitted 8 days ago • 0 comments

Identification of pyroptosis-related diagnostic model relate to immune infiltration in osteoarthritis https://www.biorxiv.org/content/10.1101/2025.02.13.638031v1

submitted 9 days ago • 0 comments

SeQuoIA: a single-cell BCR sequencing analysis pipeline for tracking selection mechanisms in germinal centres https://www.biorxiv.org/content/10.1101/2025.02.13.638132v1

submitted 9 days ago • 0 comments

Mesenchymal Stem Cell-Derived Extracellular Vesicles Mitigate Immune Cell Activation in an In Vitro Model of Post-Resuscitation Inflammation https://www.biorxiv.org/content/10.1101/2025.02.13.637856v1

submitted 9 days ago • 0 comments

Dendritic cells activate pyroptosis and effector-triggered apoptosis to restrict Legionella infection https://www.biorxiv.org/content/10.1101/2025.02.13.638189v1

submitted 9 days ago • 0 comments

Coordinated macrophage and T cell interactions mediate response to checkpoint blockade in colorectal cancer. https://www.biorxiv.org/content/10.1101/2025.02.12.637954v1

submitted 9 days ago • 0 comments

Inhibition of acute lung inflammation by a neuroimmune circuit induced by vagal nerve stimulation. https://www.biorxiv.org/content/10.1101/2025.02.12.637880v1

submitted 9 days ago • 0 comments

IMMUNOGENICITY AND SAFETY OF CHICKEN EMBRYO FIBROBLAST ADAPTED FOWLPOX VACCINE https://www.biorxiv.org/content/10.1101/2025.02.12.637982v1

submitted 9 days ago • 0 comments

Neutrophil Reprogramming Underlie Vasculopathy and Lung Disease in Systemic Sclerosis https://www.biorxiv.org/content/10.1101/2025.02.12.637866v1

submitted 9 days ago • 0 comments

Programming alphavirus with IFN-γ overrides the adverse effects of macrophages on oncolytic virotherapy https://www.biorxiv.org/content/10.1101/2025.02.12.637841v1

submitted 10 days ago • 0 comments

Immune response to co-administration of bovine tuberculosis and contraceptive vaccines in badgers (Meles meles) https://www.biorxiv.org/content/10.1101/2025.02.12.637632v1

submitted 11 days ago • 0 comments

Lymph nodes link sex-biased immune aging to compromised antigen recognition https://www.biorxiv.org/content/10.1101/2025.02.11.637693v1

submitted 11 days ago • 0 comments

Perivascular RELM-positive synovial macrophages recruit monocytes at the onset of inflammatory arthritis https://www.biorxiv.org/content/10.1101/2025.02.11.637672v1

submitted 11 days ago • 0 comments

Pneumolysin-dependent and independent non-canonical autophagy processes mediate host defense against pneumococcal infection https://www.biorxiv.org/content/10.1101/2025.02.11.637156v1

submitted 11 days ago • 0 comments

Heterogeneous T cell response patterns within established clinical phases of Hepatitis B infection revealed through the rapid functional characterization of HBV-specific T cells in whole blood https://www.biorxiv.org/content/10.1101/2025.02.11.637593v1

submitted 11 days ago • 0 comments

Splenic MARCO+ marginal zone macrophages regulate rapid production of MCP-1 and KC but are dispensable for alloantibody generation in response to stored RBCs in a murine model. https://www.biorxiv.org/content/10.1101/2025.02.11.637644v1

submitted 11 days ago • 0 comments

Genomic and functional adaptations in guanylate-binding protein 5 (GBP5) highlight specificities of bat antiviral innate immunity https://www.biorxiv.org/content/10.1101/2025.02.11.637683v1

submitted 11 days ago • 0 comments