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bugsandwalks.bsky.social
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How long should bacterial infections be treated with antibiotics? Review summarizing key RCTs & international consensus for a holistic guide to antibiotic durations, highlighting important caveats: more evidence needed for severe infections & in LMICs doi.org/10.1093/jaca... #JACAMRNews

As drug-resistant infections continue to rise, BSAC is urging the government to invest in the infection workforce by prioritising education and improved diagnostics - key interventions that can reduce the overuse and misuse of antimicrobials, the primary drivers of #AMR. bsac.org.uk/bsac-support...

This study audited the prescribing of antibiotics, using patient medical charts at a tertiary-level public hospital, in preparation for the implementation of an #AntimicrobialStewardship programme: https://doi.org/10.1093/jacamr/dlae219 #JACAMRNews #IDSky

A new article exploring important historical case studies that shaped the development, use and long-term efficacy of β-lactam #antibiotics. www.microbiologyresearch.org/content/jour...

Investing in #AMR education today shapes responsible prescribing tomorrow... but more targeted efforts are needed to tackle 'persistent misconceptions.' bmcmededuc.biomedcentral.com/articles/10....

ICYMI: this adapted UK AWaRe list reached through consensus will support national #AntimicrobialStewardship and usage targets of the UK 2024–29 NAP https://doi.org/10.1093/jacamr/dlae218 @dianeashiru.bsky.social @raseaton66.bsky.social @aliciad3.medsky.social #JACAMRNews

IV to oral antibiotic switch in patients with uncomplicated E. faecalis BSI showed shorter length of hospital stay and no significant increase in the risk of treatment failure—this could be a promising strategy for selected patients: https://doi.org/10.1093/jacamr/dlaf004 #JACAMRNews

The @biainfection.bsky.social LearnInfection platform is free to trainee members and is a brilliant resource for studying for the FRCPath Pt1/CICE exam. If you’re an early years trainee yet to sit this exam, give it a go!

‼️The @idsainfo.bsky.social cUTI guideline 📄 draft is now available for public comment🗣️! This version has been reviewed by 15+ orgs & revised according to extensive feedback provided to us. www.idsociety.org/practice-gui... UTIsky IDsky Medsky PharmSky

🔥🔥 NEW 🔥🔥 Year In Review: Top Infectious Diseases Articles From 2024 Our new post, a great collaboration with my friend 🌟 @idstewardship.bsky.social 1️⃣6️⃣⚡️🆔 RCTs 7️⃣Syst Reviews/Meta 3️⃣🌏Guidelines ✨️Wiki_Guidelines #idsky #EMIMCC #medsky #utisky EnJoy Share plz! www.idstewardship.com/year-review-...

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Come join our Infection Service in NHS Lothian as a Healthcare Science Manager! 🔬🧫 apply.jobs.scot.nhs.uk/Job/JobDetai...

250k downloads? 100 episodes? Podcast going for >3yrs 6months 3 weeks? Putting up with Callum’s crap for the same amount of time? Collabs with @febrilepodcast.bsky.social, @letstalkmicro.bsky.social, MicrobeMail & @sidpharm.bsky.social #breakpoints? COMPLETED IT MATE #idsky #humblebrag

In a retrospective cohort of asymptomatic patients with urinalysis performed within a preoperative screening protocol, the presence of pyuria increased the odds of antibiotic prescribing 4-fold 😱 Utter madness! #IDsky

UTI vs "UTI" ⁉️ In this cohort of patients diagnosed with "UTI" only about 30% had symptoms consistent with infection. ED setting and patients with mental status changes are key opportunities for antibiotic stewardship. onlinelibrary.wiley.com/doi/10.1002/...

Rethinking the “Pan-Culture”: Respiratory cultures are often obtained as part of a “pan-culture” in mechanically ventilated patients in response to new fevers or leukocytosis, despite an absence of clinical or radiographic evidence suggestive of pneumonia #idsky academic.oup.com/ofid/article...

In urinary tract infection, antimicrobial therapy matching with in vitro susceptibility predicts a clinical cure better than mismatching predicts a failure https://doi.org/10.1093/jacamr/dlae188 #JACAMRNews

Oral Versus Intravenous Antibiotic Therapy for Staphylococcus aureus Bacteremia or Endocarditis: A Systematic Review and Meta-Analysis of Randomized, Controlled Trials #IDSky

This article addresses the issue of #AntimicrobialResistance in Enterobacterales in the East of England, providing data to guide the empirical treatment of UTIs: https://doi.org/10.1093/jacamr/dlaf003 #JACAMRNews

Al Mohajer et al. found that medical school ranking did not impact the rate of antibiotic days supplied per 100 beneficiaries Students and providers with over 20 years of experience had the highest days supplied rate: https://doi.org/10.1093/jacamr/dlae191 #JACAMRNews

🆕💫 Early oral stepdown therapy for infective endocarditis: an international cross-sectional survey on current use in clinical practice ESCMID Study Group for Bloodstream Infections, Endocarditis and Sepsis #idsky #IEWiki www.sciencedirect.com/science/arti... www.sciencedirect.com/science/arti...

Antibiotic Prescribing for Respiratory Tract Infections in Urgent Care: A Comparison of In-Person and Virtual Settings #IDSky

Since RFK Jr just got confirmed today, I am taking this chance to share this wonderful @sciam.bsky.social piece on The Staggering Success of Vaccines www.scientificamerican.com/article/see-...

New guidelines for diagnosis and management of candidiasis from ECMM in cooperation with @ishamycology.bsky.social and @asm.org Led by @olivercornely.bsky.social @rosannesprute.bsky.social with contributions from >100 experts Author link: authors.elsevier.com/sd/article/S... #IDSky

The All Parliamentary Group on AMR provides a platform to engage with policymakers about AMR. Supported by the British Society for Antimicrobial Chemotherapy, its members are determined to make AMR a political priority for the UK government. Find out more about their role: tinyurl.com/3zzdrrvt

An inoculum effect in methicillin-susceptible S aureus infective endocarditis is suspected factor in higher all-cause 30-day mortality with cephazolin treatment than with oxacillin. #IDsky #Medsky

Shorter is greener! 🍃♻️ Unnecessary antibiotics contribute to greenhouse gas emmissions. Want to know how much? 👉🏻 shorturl.at/52wOT Fantastic point! #IDSky #AMSsky

Incorrect penicillin allergy (penA) labels are common and impede the use of first line narrow spectrum penicillin antibiotics This review highlights the negative impact penA has on antimicrobial resistance: https://doi.org/10.1093/jacamr/dlaf002 #JACAMRNews

This week on @idiots-pod.bsky.social, Jane is joined by Kate from @biomerieux.bsky.social to discuss 2 new devices used for early organism ID & AST in the lab: BCID2 & the VITEK Reveal! #IDsky #microsky #diagnostics #medsky podcasts.apple.com/gb/podcast/i...

Haven't posted about SNAP for a while: But we've just hit 4000 participants. Almost at 3 years since opening. And submitting two late breaker oral abstracts to ESCMID Global. @escmid.bsky.social Amazing progress and more to come. @gurujosh.bsky.social @drtoddlee.bsky.social

Development of an Electronic Clinical Surveillance Measure for Unnecessary Rapid Antibiotic Administration in Suspected Sepsis #IDSky

Clinical Challenges of Pelvic Osteomyelitis Management in Stage IV Pressure Injuries ✅ Just Accepted #IDSky

Rethinking Antibiotic Prophylaxis for Spontaneous Bacterial Peritonitis in Patients with Cirrhosis: First Do No Harm ✅ Just Accepted #IDSky

Delighted to spend time talking (inter)national (C)OPAT strategies with @raseaton66.bsky.social @bsacandjac.bsky.social in my home town - workshops, conferences, working with new friends at SIDP, new GPRs coming, stability with Oz partners, opportunities, new connections-it will be an exciting year!

Fantastic news! NHS Greater Glasgow and Clyde has become the first Scottish health board to be formally recognised for its work on antimicrobial stewardship under the BSAC-led Global Antimicrobial Stewardship Accreditation Scheme 🎉 www.nhsggc.scot/nhsggc-named...

A multistep #AntimicrobialStewardship programme has proven feasible and sustainable in improving antibiotic prescriptions in a paediatric setting: https://doi.org/10.1093/jacamr/dlae181 #JACAMRNews #IDSky

Non-invasive markers of hepatic steatosis and fibrosis following INSTI initiation in women with HIV ✅ Just Accepted #IDSky

@wiki-guidelines.bsky.social is launching a bacteremia guideline! If not previously signed up, and wish to participate, use the link below to submit your application. You will then be provided with a link to sign-up for the bacteremia one. forms.office.com/r/Tyb8R0iM8X

Before reading this excellent perspective, I had no idea that the data supporting the use of antibiotic prophylaxis for SBP were so weak. Really time to re-think this "standard-of-care" practice! Highly recommended. #IDSky doi.org/10.1093/cid/...

Antifungal resistance is increasing globally, with more patients at risk of invasive fungal disease There is an urgent need to standardise antifungal stewardship (AFS) in the UK—this position paper sets out the UK’s current AFS landscape: https://doi.org/10.1093/jacamr/dlae209 #JACAMRNews #IDSky

The Heterogeneous Syndrome of Noninfectious Causes of Persistent Fever in Neutropenic Patients With Hematologic Malignancy: Another Opportunity for Stewardship?

🚨Great article from @bsacandjac.bsky.social about the progress of the @uniofaberdeen.bsky.social UK Antimicrobial Registry (UKAR) Study. The #UKARStudy team work with hospitals and patients across the UK to collect data on antibiotics used for #antimicrobialresistance 🦠 bsac.org.uk/uk-antimicro...

Rethinking Antibiotic Prophylaxis for Spontaneous Bacterial Peritonitis in Patients with Cirrhosis ➡️Standard of care since the 1990s and is currently recommended by several major GI societies ➡️Weak supporting evidence ➡️No clear mortality benefit doi.org/10.1093/cid/... #IDSky

COI: I’m presenting at this! So I can guarantee the high quality of all but one of the talks. Sign up today! (I’m taking on the new BL/BLI combinations & Cefiderocol*) *the Trojan Horse

Thanks to @absteward.bsky.social who always finds new studies first! TB is indeed complex. For rif-resistance, we had a 6 mo novel regimen vs. 9-20 mo standard therapy RCT. Now we add an RCT comparing 5 novel regimens, 4 were NI to 18-24 std therapy. Tables updated! bradspellberg.com/shorter-is-b...

ONE ANTIBIOTIC PK TABLE TO RULE THEM ALL Absorption takes drug into blood from GI, Vd spreads drug out to where bug calls home. And after bacteria are doomed to die, The drug’s eliminated on the porcelain throne In the Land of Notion where this table doth lie… #idSky #microsky #pharmsky #medsky

NEW PODCAST!! This week, Jame is joined by Nick & Dal from BioMerieux to talk about the Vitek2, a machine for organism ID & automated antibiotic sensitivity testing! What does it do & how does it do it? Listen & find out! #idsky #medsky #antibiotics #microsky podcasts.apple.com/gb/podcast/i...

Since it's launch in 2023, The UK Antimicrobial Registry (UKAR) has seen an exponential rise in the number of hospitals participating and the number of recruited patients. In this short update, we explore what has been happening with UKAR during 2024 and plans for 2025. bsac.org.uk/uk-antimicro...