caina89.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

I just had the most wonderful time at the Quantgen GRC in Italy with these lovely and brilliant people :) hope to see everyone again in Ventura for the next Quantgen GRC in 2 years time, and sooner on other occasions!

submitted 6 days ago • 0 comments

New year new start! My group has moved to the Dept of Biosystems Science and Engineering in ETH Zurich - very excited to work with new colleagues here! We’re also hiring soon, if interested in a PhD/postdoc in quantitative genetics and genomics, esp with focus in psych disorders, pls get in touch!

submitted 22 days ago • 3 comments

How population stratification makes environments look like genes. A short 🧵:

submitted 37 days ago • 7 comments

Unsure how recent changes in U.S. policy regarding the NIH will impact the psychiatric genetics world? You're not alone. Join ISPG for a Member’s Meetup for community discussion and support: 📅 Wednesday, January 29 🕗 3 PM EST 📍 Pre-Register: us06web.zoom.us/meeting/regi...

submitted 33 days ago • 0 comments

📢 Quantgen friends: We will continue to accept applications for the GRC on Quantgen in Feb 2025 till 26 Jan or when we are full, so there is still time to put in an application and join us! 😁 Check out our latest program and apply now! www.grc.org/quantitative...

submitted 37 days ago • 0 comments

🚨 RECOMB-Genetics Deadline 🚨 The RECOMB-Genetics 2025 workshop is in Seoul 🌏 on April 25, 2025, just before the main RECOMB conference (April 26–29). 📅 Submission deadline: Feb 14, 2025 (AoE) 👉recomb.org/recomb2025/rec… Submit your work and join us for this exciting event!

submitted 43 days ago • 0 comments

I wrote about the ongoing debates over genomic data sharing and the use of such data for "abhorrent science", including some perspective papers that came out last month. A few key points: 🧵

submitted 45 days ago • 4 comments

Quantgen GRC (16-21 Feb 2025) in Lucca, Italy: we are still accepting applications and poster abstracts! Deadline: 19 Jan 2025 Apply now - we have a great selection of invited speakers and the posters abstracts are amazing. It’s going to be a blast 💥 www.grc.org/quantitative...

submitted 48 days ago • 0 comments

How to do differential expression with scRNAseq data? State of the art is "pseudo-bulk" analysis with RNA-seq methods like edgeR or DESeq2, where "cell type" is encoded as discrete categories. Biologically, discrete categories are not always the most appropriate concept.(1/3) doi.org/10.1038/s415...

submitted 54 days ago • 7 comments

Come join us as a group leader: www.jobs.cam.ac.uk/job/49356/ Happy to answer queries.

submitted 57 days ago • 1 comment

Great to see this out. From @caina89.bsky.social and @pgcgenetics.bsky.social Cross-disorder group rdcu.be/d4ZF0

submitted 61 days ago • 0 comments

Last work tweet of 2024 (maybe 😉): I, Ken Kendler, Brad Verhulst, @jorsmo.bsky.social and @andrewgrotzinger.bsky.social et al in the Psychiatric Genomics Consortium Cross Disorder Group (PGC-CDG) wrote a review on challenges studying cross disorder (psych) genetics: www.nature.com/articles/s41...

submitted 61 days ago • 2 comments

Very happy to share two new projects from my group now on @biorxivpreprint.bsky.social on mtDNA variation effects on tissue-specific gene expression conducted using RNAseq data in 49 tissues in the GTEx project! 🧵 1/n

submitted 70 days ago • 1 comment

After 4 fantastic years of research, together with @caina89.bsky.social & Matthias Heinig, I’m thrilled to share the first tissue specific map of apparent mtDNA heteroplasmy in humans and their relationships with donor age and mtDNA gene expr across 49 tissues! www.biorxiv.org/content/10.1...

submitted 70 days ago • 2 comments

My first PhD student Lianyun Huang has now successfully defended her PhD and is now Dr Huang! 🎉🎉🎉 Thank you for 4 years of hard work, it’s an honor to be part of your academic journey!

submitted 76 days ago • 0 comments

Quantgen GRC (16-21 Feb 2025) updates: we are now 75% subscribed! Deadline: 19 Jan 2025 BUT: We will pick talks from submitted abstracts 16 Dec and aim to send decisions before Xmas. So submit your abstracts now (even if not perfect - editable after submission)! www.grc.org/quantitative...

submitted 84 days ago • 0 comments

New work by Andy Dahl and Michal Sadowski on using GxE to study genetics of drug response now out in Cell Genomics www.cell.com/cell-genomic...

submitted 84 days ago • 0 comments

New paper by Andy Dahl and I on phenotype integration improving GWAS power while preserving specificity is now out in Nature Genetics 🧬🎉 thank you all collaborators and reviewers! www.nature.com/articles/s41...

submitted 463 days ago • 0 comments

Dear statgen friends at #ASHG2023 #ASHG23, my lab is #hiring #phds #postdocs to work on heterogeneity and trajectories of psychiatric disorders using EHR/cohorts across US/Europe/Asia (incl. data from PGC), lots of cool stuff to be done! Please reach out by email! Ad link: tinyurl.com/7tae8k

submitted 480 days ago • 0 comments

Feeling FOMO big time seeing all the #ASHG2023 posts, sadly I’m not there this year! 🥲 My PhD student Jolien Rietkerk is there though and she has a poster (PB4102), go say hi to her and she can tell you about how PRS can be used to find pathways (using method by Andy Dahl, David Tang)✨

submitted 480 days ago • 0 comments

On the problem of inflation in TWAS Does TWAS yield inflated p-values?

submitted 497 days ago • 3 comments

Hi #WCPG2023, it’s been a great few days! But more today 😉: I’m talking about my work with Andy Dahl on phenotype integration and PRS specificity in the symposium on GWAS phenotyping, 3pm in Rm 510, with Travis Mallard, Justin Tubbs, Jeanne Savage and Abe Palmer. Come join us!! Preprint linked:

submitted 502 days ago • 0 comments

Hi #wcpg2023! Today: my student Lianyun Huang is gonna talk about MDD symptoms assessed in the UKBiobank in the PGC session on mental health research using UKB data! ✨ Where/When: 4pm in Rm 510, with Ben Lacey, Ana Lucia Espinosa Dice and Cathryn Lewis 🤩 Come hear her out!

submitted 503 days ago • 0 comments

The "we did a lot of stuff" talk is always so tempting as a speaker. It's fun for you, but not for your audience. Cut those slides - just do it. Less data, more drama.

submitted 561 days ago • 1 comment

Good morning #wcpg2023! Today: My student Jolien Rietkerk is giving a talk at 1pm in the Stats Methods session (Rm 510) on use of PRS in pathway interaction test + method considerations; Lianyun Huang is giving a poster (no 74) on MDD symptom genetics. Come hear them out, feedback welcome! 🤩

submitted 504 days ago • 1 comment

One week left to apply for junior faculty positions in the Data Driven Life Science program in Sweden! Competitive startup, big program with a strong peer+mentorship networks, great country with strong science, international vibe and nice quality of life. www.scilifelab.se/data-driven/...

submitted 507 days ago • 0 comments

On our way to #wcpg2023! This is a big year for Cai lab, all of us have talks! 🤩 Lianyun Huang is in the UKB session, Jolien Rietkerk is in the stats methods session, and I’m in a symposium on GWAS phenotyping. I’ll remind everyone on the morning of. 😉 See you all in Montreal!

submitted 506 days ago • 0 comments

I'm recruiting PhD students for Oct 24 start at University of Bath. Fully funded for UK students only. If interested in developing data structures/algorithms for bacterial genomics, or exploring plasmid epidemiology, or ML/AI on bacterial/phage geno/pheno data, give me a call!

submitted 511 days ago • 2 comments

Less than a week to #wcpg2023, looking forward to seeing everyone there! My lab is hiring postdocs to work on quantgen methods, EHR utilisation, disease heterogeneity and trajectories, if interested please email me, also happy to chat during the conference! www.nacailab.com

submitted 511 days ago • 0 comments

I'm delighted to release the first half of my new textbook in human genetics: web.stanford.edu/group/pritch... "An Owner's Guide to the Human Genome: an introduction to human population genetics, variation and disease"

submitted 514 days ago • 8 comments

bioRxiv goes big on Bluesky: accounts for all subject categories now available (Please Reskeet) connect.biorxiv.org/news/2023/09...

submitted 517 days ago • 9 comments