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calin.bsky.social
Assistant Prof. @uoknightcampus.bsky.social. Cofounder @synplexity.bsky.social. Gene synthesis, synbio, protein engineering, nanopores, multiplex assays. Opinions my own. www.plesalab.org
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New preprint! We carried out the largest complementation and inhibition study for diverse homologs in a single protein family (DHFR) to date. Highlights thread follows... 1/n 🧵

submitted 27 days ago • 1 comment

Great article. That last quote from Zhu sums it up: “The devil is in the details, and there are a lot of devils.”

submitted 63 days ago • 0 comments

Let's talk about how close we are to a cell-free mirror image central dogma in a tube, aka Mirror-PURE! This topic has been getting a lot of attention due to the recent @science.org letter (www.science.org/doi/10.1126/...) outlining the threats posed by mirror life. 1/n

submitted 63 days ago • 3 comments

Today we report that an engineered skin bacterium, swabbed gently on the head of a mouse, can unleash a potent antibody response against a pathogen. Could lead to topical vaccines that are applied in a cream. @djenetbousbaine.bsky.social led the charge... @natureportfolio.bsky.social 1/55

submitted 74 days ago • 24 comments

Congrats to Knight Campus assistant professor @calin.bsky.social on his grant from the MJ Murdock Charitable Trust through its Commercialization Initiation Program! The award includes matching funds from the #KnightCampus and @universityoforegon.bsky.social Research: bit.ly/49hs1LI

submitted 83 days ago • 0 comments