carlstrom.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

Or, this could be YOU, if you choose to attend "Woodstock.Bio2 + Night Science" - the craziest and best conference of all time!!! (less than a month away!) woodstock.img.cas.cz #theconferencetoendallconferences

submitted 24 days ago • 0 comments

Postdoc positions available in my lab @ki.se Sweden - exciting science, fantastic environment and great quality of life. I take mentoring seriously - 7/7 postdocs that left my lab has faculty positions today. Existing datasets and funds to build new ones available. ki.varbi.com/en/what:job/...

submitted 6 days ago • 0 comments

We're thrilled to share the published version of our DRT9 story, online today @nature.com! Congratulations to all authors! www.nature.com/articles/s41...

submitted 11 days ago • 0 comments

Happy to share that I will kickstart my research group at @ki.se this autumn!🎉🎉 Are you interested in glial biology, using high-end tools for gene and cell programming to study metabolic and epigenetic interactions? Stay tuned! Will be 🔭 for RA, PhD-students & postdocs! Let the journey begin! 🧬🧫🔬

submitted 11 days ago • 3 comments

Happy to share that I will kickstart my research group at @ki.se this autumn!🎉🎉 Are you interested in glial biology, using high-end tools for gene and cell programming to study metabolic and epigenetic interactions? Stay tuned! Will be 🔭 for RA, PhD-students & postdocs! Let the journey begin! 🧬🧫🔬

submitted 11 days ago • 3 comments

Huge thanks to the #GLIA2025 Programme Committee, led by Marc Freeman (Portland, USA), for shaping an outstanding scientific agenda! Grateful to all speakers + contributors for making this congress in Marseille unforgettable. 🙌🎓 🔗 glia2025.eu/committees

submitted 12 days ago • 0 comments

Today!

submitted 13 days ago • 0 comments

David Liu @harvard.edu beautifully articulates the criticality of basic science funding for developing revolutionary therapeutics like life-saving base editors 👏 youtu.be/8YhJM6zxYDw?...

submitted 16 days ago • 1 comment

1/2 Planning to perform single nuclei RNA-sequencing (snRNA-seq) experiments in complex tissues? We performed a head-to-head comparison with five different methods on human post-mortem brain tissue. Check out the benchmarking in our new preprint. papers.ssrn.com/sol3/papers....

submitted 17 days ago • 1 comment

A recent preprint from the lab. Turns out biology trumps technical measures for benchmarking of transcriptomics.

submitted 15 days ago • 0 comments

Interested in brain metabolism and #lactate? Join us for this fantastic symposium in lovely Bordeaux!! Astro-neuron lactate shuttle,+ microglia, oligos etc! Program: lnkd.in/eP7Ccv4s 📅 Registration (until June 5): lnkd.in/ejkjUApV ⌛ Abstracts (young researchers, deadline June 5): lnkd.in/edhdTr2p

submitted 17 days ago • 0 comments

Join an interdisciplinary workshop exploring the latest advances in #CRISPRCas – spanning #genomics to #StructuralBiology – at EMBO Workshop "CRISPR-Cas: From biology to therapeutic applications" in Sorrento, Italy, 2–5 November 2025 Deadline: 30 June buff.ly/LsAMHk2 #EMBOCRISPRcas #EMBOevents 🧪

submitted 17 days ago • 0 comments

One thousand candidate enhancers tested in vivo in the mouse brain! A massive resource and oh so useful as validation set for genome-wide enhancer prediction methods. Super fun to be involved in one of the papers: ‘the prediction challenge paper’ by Nelson&Niklas et al www.cell.com/cell-genomic...

submitted 18 days ago • 0 comments

Are you attending #GLIA2025? Don't miss our workshop on CRISPR/Cas technologies and iPS cells in glia research, chaired by me and Prof Tanja Kuhlmann. Hope to see you there!

submitted 22 days ago • 0 comments

Have you seen our #GLIA2025 workshops? 🔬 From Molecules to Manuscripts 📚 Four dynamic sessions diving into the tools, models & methods driving glial science forward. Don’t miss them! #Neuroscience #GlialCells #GliologistsTogether

submitted 23 days ago • 0 comments

1/10 Today in @science.org in collaboration with the Liu group we report the development of a laboratory-evolved CRISPR-associated transposase (evoCAST) that supports therapeutically relevant levels of RNA-programmable gene insertion in human cells. drive.google.com/file/d/1I-Ub...

submitted 24 days ago • 2 comments

Are you attending #GLIA2025? Don't miss our workshop on CRISPR/Cas technologies and iPS cells in glia research, chaired by me and Prof Tanja Kuhlmann. Hope to see you there!

submitted 22 days ago • 0 comments

Night science is improvisations, openness, import/export, puzzle switching, hypothesis liabilities, anthropomorphisms, finding questions, contradictions & awe in science; as we discussed in the legendary Karolinska Institute. 🙏 @kragesteen-lab.bsky.social Christoph Ziegenhain & Rickard Sandberg

submitted 23 days ago • 1 comment

It was a really inspiring visit today at the Karolinska Institute. Thank you to @kragesteen-lab.bsky.social and Christoph Ziegenhain for being amazing hosts. I'm looking forward to the Night Science workshop there tomorrow!

submitted 25 days ago • 0 comments

It was amazing to do a Night Science workshop today at the Karolinska Institute in Stockholm!

submitted 24 days ago • 0 comments

Today "a milestone in the evolution of personalized therapies for rare & ultra-rare inborn errors of metabolism" —the 1st human to undergo custom genome editing —from decades of NIH funded research www.nejm.org/doi/full/10.... @nejm.org www.nejm.org/doi/full/10.... www.nytimes.com/2025/05/15/h...

submitted 24 days ago • 10 comments

Extensive differences observed in 3D genome structure between homologous heterozygous chromosomes revealed by Genome Architecture Mapping #GAM in the @apombo1.bsky.social lab ➡️ www.embopress.org/doi/full/10....

submitted 24 days ago • 0 comments

#Proteins build our cells send signals and transport substances They will only work if they attain their exact 3-dimensional form Gunnar von Heijne is demonstrating at a previously inconceivable level of detail how protein folding is achieved @stockholm-uni.bsky.social #science tinyurl.com/53n9s4nv

submitted 24 days ago • 0 comments

Neuronal activity influences the growth of #myelin sheaths along axons by signalling through metabotropic glutamate receptor 5 (mGluR5) on oligodendrocytes 🧪🧠 www.nature.com/articles/s41...

submitted 24 days ago • 0 comments

I'm very excited to share our latest work with #zebrafish published in @mucosalimmunol.bsky.social!! 🐟 www.sciencedirect.com/science/arti... Here, we characterized a genetic model of intestinal epithelial cell ablation to study the cellular and molecular mechanisms of intestinal #regeneration....

submitted 25 days ago • 3 comments

1/9 🚀 Our latest findings in @cp-devcell.bsky.social : #Neuroblastoma cells aren’t locked into one single fate—they flip between developmental programs, driving tumor heterogeneity and malignancy. www.sciencedirect.com/science/arti...

submitted 30 days ago • 2 comments

Join us at the Nobel Symposium Multiple Sclerosis: Past, Present and Future Treatment June 5th, 2025 | Jacob Berzelius lecture hall @ki.se | Stockholm, Sweden free registration at: jirango.com/cview/web/f0...

submitted 34 days ago • 1 comment

Excited to share this new work led by the talented Mike Dolan @dolan in collaboration with Evan macosko See below for details and preprint

submitted 41 days ago • 0 comments

I’m thrilled to share that this week I’m joining @michellemonje.bsky.social lab as a postdoc, supported by a generous fellowship from Hjärnfonden. I can’t wait to dive into new projects and explore the exciting field of #cancerneuroscience.

submitted 41 days ago • 2 comments

PERSPECTIVE | H Ren, Y Tang and D Zhang ( PKU, CN; @umich.edu ) Read this Perspective on protein L-lactylation in regulating cellular metabolism and signaling and as a therapeutic target

submitted 41 days ago • 0 comments

Check out our paper, now extensively revised and published in @cp-molcell.bsky.social! This has been a real tour de force led by Stephanie Sansbury and @ysereb.bsky.social and we are very excited about the findings and future potential of this approach www.cell.com/molecular-ce...

submitted 46 days ago • 2 comments

In @nature.com we describe the use of scalable #proteinengineering & #machinelearning to predict millions of bespoke CRISPR enzymes, offering safer & more efficient genome editing tools 🧬🖥️ @rachelsilverstein9.bsky.social @mgbresearch.bsky.social @harvardmed.bsky.social www.nature.com/articles/s41...

submitted 47 days ago • 3 comments

New preprint exploring how transplanted human glial progenitors mature and differentiate in vivo 🧬 www.biorxiv.org/content/10.1...

submitted 46 days ago • 1 comment

Microglia & monocyte-derived cells were long assumed to have similar functions during remyelination. Our new paper @plosbiology.org shows non-redundant roles, with monocytes ultimately inhibiting remyelination. Team effort by Bianca Hill,Rebecca Holloway, Lindsey Forbes,Claire Davies plos.io/3RryCLF

submitted 47 days ago • 2 comments

Immune attacks on ion and water homeostasis in astrocytic endfeet as a primary event in MS?

submitted 53 days ago • 0 comments

Glycolysis drives early embryonic cell decisions

submitted 53 days ago • 0 comments

ICYMI: New online! Multiple sclerosis: an immune attack on astrocyte-mediated ion and water homeostasis

submitted 59 days ago • 0 comments

Silencing of transgenes during iPSC differentiation is a frequent problem. 🧬🫢 Check out the piggyBac system below, which has resisted silencing in many protocols across many labs. 💪 Excited that our lab could contribute to this team effort led by @tuenaka.bsky.social & Marius Wernig!

submitted 53 days ago • 0 comments

Marseille is calling! 🇫🇷🌊☀️ Join us at #GLIA2025, where cutting-edge science on #glia cells meets the charm of the French Mediterranean. 📍 Marseille | 8–11 July 2025 🎥 Watch the GIF & get a taste of Marseille’s vibrant energy! 🌐 Register here: glia2025.eu

submitted 54 days ago • 0 comments

Trump's moves are already imposing immense costs on the United States and on the world via lost scientific progress on preventing Alzheimer's, curing cancer, etc.

submitted 55 days ago • 14 comments

Continuing a project that a former student left unfinished

submitted 60 days ago • 2 comments

PhD Position Available! 🧑‍🎓🧠🧬 We’re looking for a motivated PhD student to join our team and explore the fascinating world of human brain development and evolution. su.varbi.com/what:job/job...

submitted 62 days ago • 1 comment

Hot off the press! 🧬🔬 We developed in utero nano-injection to label & trace the mouse neural plate and otic placode using next generation single cell lineage tracing. We couple progenitors to mature cell types in the CNS & resolve the lineages of cells in the hearing organ: doi.org/10.1126/scie...

submitted 65 days ago • 9 comments

“I feel very proud every time I see an article published using data we at NGI helped generate” says Elísabet Einarsdóttir, project coordinator at @scilifelab-ngi.bsky.social. Full interview ↓🧪 www.scilifelab.se/news/scilife... #ResearchInfrastructure

submitted 108 days ago • 1 comment

Identification of distinct neural ensembles in the adult mouse spinal cord encoding mechanical and heat #pain 🧠🧪 @patrikernfors.bsky.social www.nature.com/articles/s41...

submitted 72 days ago • 0 comments

our work on the molecular differences between transcription factor isoforms is out now in Molecular Cell! key point: 2/3rds of TF isos differ in properties like DNA binding & transcriptional activity many are "negative regulators" & misexpressed in cancer www.sciencedirect.com/science/arti...

submitted 74 days ago • 7 comments

Runners appear to experience a decrease in the amount of myelin in certain regions of the brain following a marathon, according to a study of 10 participants in Nature Metabolism. The effect, however, was completely reversed two months after the marathon. https://go.nature.com/4iDd62r 🧪

submitted 76 days ago • 0 comments

How is the input of the different kinds of primary sensory neurons responding to heat and mechanical stimuli summarized in the spinal cord? Check out our recent study. www.nature.com/articles/s41...

submitted 76 days ago • 0 comments

"But what did he publish since?"

submitted 83 days ago • 3 comments