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cedricboeckx.bsky.social
Evolution, Genetics, Cognitive Science, Language
243 posts 1,453 followers 196 following
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Posts 21 Comments 29

"Genes are... the easy part" @philipcball.bsky.social argues biologists need to embrace complexity from the start, rather than beginning with oversimplified "one gene, one trait" models +1 www.cell.com/cell-systems...

submitted 3 days ago • 3 comments

Very interesting study by @a-urciuoli.bsky.social & colleagues, offering insight into the derived morphology characterizing the Neanderthal clade. Reduction in bony labyrinth disparity linked to underlying genetic variation resulting from bottleneck events H/t @chrisbstringer.bsky.social

submitted 3 days ago • 0 comments

Beautiful new work by @itsmeawais.bsky.social @estherkli.bsky.social @djabaudon.bsky.social @silvianeuro.bsky.social @mveronicapravata.bsky.social & L. Gomez, probing evolutionary changes in the developmental expression of shared genes, focusing on the cortex. Key role for JUNB in human 🧠 👇🧬🧫🧪

submitted 4 days ago • 0 comments

✨ We tend to think of species-specific differences as resulting from the presence of species-specific genes. In our latest work with @djabaudon.bsky.social, we show that building brains is not only about which genes you use, but also about when and where you do. www.biorxiv.org/content/10.1...

submitted 4 days ago • 6 comments

New preprint w/ @soumyakundu.bsky.social @sbmontgom.bsky.social @anshulkundaje.bsky.social ! Using deep learning & scATAC-seq, we studied context-specific variants in disease & evolution, and introduce FLARE for de novo mutations—w/ application to autism-affected families. doi.org/10.1101/2025...

submitted 5 days ago • 0 comments

Very cool preprint by @zhoujoeyyi.bsky.social and members of the Ming and Song labs, offering a detailed comparison of the molecular landscape of immature neurons in the mammalian dentate gyrus, revealing special features in humans 🧪🧬🧠 www.biorxiv.org/content/10.1...

submitted 6 days ago • 1 comment

Fascinating new study led by Yoko Tajima and @darnelr.bsky.social, revisiting the impact of the ‘sapiens’-specific protein-coding mutation in NOVA1 — here showing that vocalisations are impacted in a humanised mouse model 🧪🧬🧠🐭 www.nature.com/articles/s41...

submitted 6 days ago • 1 comment

Please don’t stop sharing and posting your science because of the current attack on it, it is still valuable and reminds us what the fight is for

submitted 7 days ago • 3 comments

🚀 Excited to share our latest work uncovering TGIF2 as a key transcription factor (TF) safeguarding neural stem cell (NSC) fate and regulating neurogenic priming! 🧠 🔗 biorxiv.org/content/10.1101/2025.02.13.635953v1 Here’s how we found it and why it’s important!🧵👇

submitted 7 days ago • 2 comments

Insightful study by L. Dony @anthikrontira.bsky.social @drcricru.bsky.social @binderlabmpip.bsky.social @silvianeuro.bsky.social @fabiantheis.bsky.social on the effects of chronic exposure to glucocorticoids for neurodevelopment. Organoid model reveals amplification of inhibitory neuron cell fate 🧪

submitted 9 days ago • 1 comment

Chronic exposure to glucocorticoids amplifies inhibitory neuron cell fate during human neurodevelopment in organoids | Science Advances www.science.org/doi/10.1126/...

submitted 10 days ago • 1 comment

Great job opportunity @dev-journal.bsky.social; wonderful journal for developmental biology 🧪👇

submitted 10 days ago • 0 comments

Three fantastic @science.org papers on convergent development & evolution of neurons + their connections in the bird & mammalian pallia, by @kaessmannlab.bsky.social @steinaerts.bsky.social & Fernando García-Moreno. Expertly synthesised by @giacomogattoni.bsky.social & Maria Antonietta Tosches 🧪🧠

submitted 10 days ago • 2 comments

Big shoutout for the #cerebellum in this excellent @cp-trendscognsci.bsky.social piece by @aniladmello.bsky.social @0xwbj.bsky.social @amandalebel.bsky.social 🧠 “Ignoring the cerebellum is hindering progress in neuroscience” (and I may add, brain evolution) www.cell.com/trends/cogni...

submitted 12 days ago • 1 comment

Big shoutout for the #cerebellum in this excellent @cp-trendscognsci.bsky.social piece by @aniladmello.bsky.social @0xwbj.bsky.social @amandalebel.bsky.social 🧠 “Ignoring the cerebellum is hindering progress in neuroscience” (and I may add, brain evolution) www.cell.com/trends/cogni...

submitted 12 days ago • 1 comment

Very good new preprint by @nanamatoba.bsky.social @hyejungwon.bsky.social @steinlab.bsky.social, using a Massively Parallel Reporter Assay to gain insight into regulatory elements associated with inter-individual differences in cortical structure (Wnt response sensitivity plays a prominent role)🧪🧠🧬

submitted 12 days ago • 0 comments

Greetings to all developmental cortical people. We have moved over from X to bluesky and will keep you updated about our meeting from here! This years meeting is in Naxos Sicily from May 25th-28th. Here is the link for registration! corticaldevelopment.wordpress.com

submitted 14 days ago • 0 comments

Interesting approach developed by @mjschipper.bsky.social & @daniposthu.bsky.social to predict the effector genes that mediate the locus-trait associations uncovered by GWAS; out in @naturegenet.bsky.social www.nature.com/articles/s41...

submitted 13 days ago • 0 comments

EMBO Population Genomics course: Are you a postgrad student or a postdoc starting a population genomics project? This course aims to give you the tools to answer questions for your project. Registration deadline: 24 February 2025 meetings.embo.org/event/25-pop... #EMBOpopgen

submitted 17 days ago • 0 comments

Great new preprint (study led by @steinlab.bsky.social) showing how brain organoid modeling can capture inter-individual variability in infant brain growth trajectories (early cell cycle genes in cortical organoid progenitors & cortical surface area expansion) 🧪🧠🧫🧬 www.biorxiv.org/content/10.1...

submitted 16 days ago • 0 comments

Cortical maturation unfolds hierarchically, endowing the PFC with extended plasticity. But do timeframes of plasticity vary across PFC layers? With 7T quantitative myelin imaging, EEG, and cognitive data, we uncover heterochronous laminar maturation in the PFC 1/n. www.biorxiv.org/content/10.1...

submitted 17 days ago • 4 comments