chemb.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

RNA xkcd.com/3056

submitted 16 hours ago • 135 comments

When I worked in UK academia I recall hearing of a Japanese man who was baffled at how Britain had decided to run its universities like firms. “Why? Your universities are excellent and your firms are terrible.”

submitted 1 day ago • 20 comments

I didn’t need another reason to say no to that predatory conference invite to Chicago, but in case I did…

submitted 22 hours ago • 0 comments

Plan To Be More Positive Off To Shitty Fucking Start theonion.com/plan-to...

submitted 3 days ago • 26 comments

I think people both within science and outside science don’t fully appreciate the miracle that were the Covid-19 vaccines. How much courage it took to get the sequence out, how much work had already gone into figuring out the best viral antigen and how best to present it. 1/

submitted 3 days ago • 8 comments

Important FYI: if you’ve run out of prescribed meds, a pharmacist can give you them without a prescription in an emergency.

submitted 3 days ago • 5 comments

We are recruiting a Higher Scientific Officer experienced in recombinant protein production and assay development to join an exciting collaboration to develop novel small molecule-controlled molecular switches to modulate CAR-T cell activity. jobs.icr.ac.uk/vacancies/11...

submitted 5 days ago • 0 comments

Are you interested to work in cancer drug discovery? Come and join us, we are recruiting a protein crystallographer to strengthen our structure-based drug discovery efforts. jobs.icr.ac.uk/vacancies/11...

submitted 5 days ago • 0 comments

@dereklowe.bsky.social is consistently brilliant to read on anything, but this is superb. “all the care and forethought of a three-year-old left alone with a reciprocating saw” made me spit my drink everywhere

submitted 7 days ago • 0 comments

So one of the things that I think is lost on AI proponents is what I call the card catalog effect, a thing I shouldn’t call it because a lot of people probably have no experience with a card catalog.

submitted 9 days ago • 105 comments

I tell this story in class every year. Acetylated salicylic acid and got a better product. Tried the same approach with morphine two weeks later. I like to imagine Felix sitting at the back of meetings for the rest of his career saying “Have you tried acetylating?” and everyone rolling their eyes

submitted 9 days ago • 1 comment

I should have mentioned that this is a collaboration with @thesgc.bsky.social University of North Carolina and acknowledged the Chordoma Foundation and Mark Foundation. Thanks to Prof. Workman for pointing out this omission. I’m not involved in this but always happy to highlight great team science!

submitted 10 days ago • 1 comment

You: They did the math. Me: ᵀʰᵉʸ ᵈⁱᵈ ᵗʰᵉ ᵐᵒⁿˢᵗᵉʳ ᵐᵃᵗʰ You: What was that? Me: Nothing. Me three hours later in a whisper: ᴵᵗ ʷᵃˢ ᵃ ᵍʳᵃᵛᵉʸᵃʳᵈ ᵍʳᵃᵖʰ

submitted 13 days ago • 44 comments

www.theguardian.com/science/2025... Nice write up of @icr.ac.uk research on rare cancer

submitted 11 days ago • 0 comments

🚨 New paper alert! 🚨 Excited to share our latest work in Nature Communications spearheaded by brilliant @omaiques.bsky.social and thanks to all our collaborators—we show how matrix mechano-sensing at the invasive front induces a cytoskeletal and transcriptional memory that supports metastasis! 🧵⬇️

submitted 12 days ago • 1 comment

Vaccines are one of (well, many of) the most amazing human inventions, saving over 150 million lives. Children under 1 year old represent 100 million of those. www.thelancet.com/journals/lan...

submitted 13 days ago • 0 comments

Yes. This. Wikipedia is a great example of how things should work, and it still amazes me that it actually does work as well as it does. Just a load of people willing to share their expertise, largely self policed.

submitted 13 days ago • 0 comments

As outcry builds over Trump cuts to NIH payments, drugmakers are MIA On last night's earnings call, $VRTX CEO Reshma Kewalramani said nothing about the NIH, yet Vertex owes some of that $11B in cystic fibrosis drug sales to foundational biomedical research funded by NIH....

submitted 15 days ago • 6 comments

Even after being assured this wasn’t a joke I still had to go and check for myself www.congress.gov/bill/119th-c...

submitted 15 days ago • 9 comments

1. Today the NIH director issued a new directive slashing overhead rates to 15%. I want to provide some context on what that means and why it matters. grants.nih.gov/grants/guide...

submitted 19 days ago • 270 comments

Explore this gift article from The New York Times. You can read it for free without a subscription. www.nytimes.com/2025/02/07/b...

submitted 18 days ago • 0 comments

@bmix.bsky.social I’m hoping bindingDB is just temporarily down and not somehow a victim of the Trump-Elon destruction gangs? An amazing resource, especially of data from patents which are not well curated elsewhere! Thanks

submitted 19 days ago • 1 comment

Ah damn it. Too late for me but in case this is helpful

submitted 20 days ago • 0 comments

For cancer biologists looking for a change of scene, job, or even country… we are advertising for someone to head up our Centre for Target Validation and bring through new cancer drug targets: jobs.icr.ac.uk/vacancies/47... Based on our campus in Sutton, south London

submitted 22 days ago • 0 comments

I want to spell out the basic reason it’s so dangerous for Elon to have control of the U.S. payments system. It may seem like a technical matter, but the dynamics are simple. 1/x

submitted 24 days ago • 166 comments

The greatest local Facebook drama in history

submitted 27 days ago • 15 comments

This was how I reacted when I first discovered that when writing a text on an iPhone you can hold down the spacebar and the keyboard becomes a trackpad

submitted 28 days ago • 13 comments

Happy to be part of the team for the Chemical Probes Hackathon in Vienna on 20th Feb. If you are a PhD student or postdoc in the area, join us to learn how to assess whether a molecule is suitable for use in your experiments, and help build this free resource www.chemicalprobes.org/hackathons/e...

submitted 28 days ago • 1 comment

Our Xitter account is now dormant so if you follow us over here: THANKS! It's a bit scary as a tiny business to be effectively losing 90% of our followers but Elon's a big fash prick, so. There'll be new drawings next week but in the meantime, here's our shop full of wonky nonsense noscoredraws.com

submitted 36 days ago • 28 comments

Join us for this exciting event! 🚀 🚀 🚀 Registration: lnkd.in/d6yiTkUi

submitted 47 days ago • 1 comment

Opportunity for medicinal chemist MSD (London UK) ref: R324173 | closing: 03-Feb-2025 #MedChem #SynChem #UKChemJobs #ChemJobs #chemsky 🧪 jobs.msd.com/gb/en/job/R3...

submitted 49 days ago • 0 comments

It is driving me slightly mad that every time I search for something on the internet, many of the websites are clearly just paragraphs of AI written vague nonsense. Please can I search the 2015 internet instead, or has anyone devised a search engine that downprioritises this drivel?

submitted 52 days ago • 1 comment

A rigorous study of UPS tool compounds for #degrader evaluation is published by Stefan Knapp @thesgc.bsky.social in ACS Chemical Biology! They determine the optimal doses of UPS pathway inhibitors that rescue degradation without displaying off-target activity and toxicity. dx.doi.org/10.1021/acsc...

submitted 53 days ago • 1 comment

Happy Rare Square Number New Year!* The last one was 1936, the next one 2116. *HT to my teenager for this nugget of info explained to us at midnight.

submitted 56 days ago • 1 comment

A reminder to download Libby for access to ebooks, magazines and audiobooks. Cuts down on return fees. 🤪😬 #booksky #library

submitted 59 days ago • 0 comments

Punctuation matters. Way more than you think. Bad punctuation can be devastating. Don't believe me? Alright, then gather around, children, because I'm going to tell you a short true story about how not understanding ONE punctuation mark once cost a company millions of dollars in a lawsuit.

submitted 64 days ago • 68 comments

Ending the year (well, not quite) with one successful and one unsuccessful small grant application, both announced today. Can’t win ‘em all and going to be a busy 2025 in any case!

submitted 68 days ago • 0 comments