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chuckherring.bsky.social
Former US Marine, General Contractor, graduate student in Lau Lab, and current postdoc in the Lister Lab. Single cell genomics and epigenetics. Bioinformatics, and Neuronal Development πŸ’»πŸ§¬πŸ‡¦πŸ‡Ί
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Metabolic Atlas of Early Human Cortex Identifies Regulators of Cell Fate Transitions https://www.biorxiv.org/content/10.1101/2025.03.10.642470v1

Heading to #lornegenome25 #LorneCancerConference ? Looking for a computational postdoc to work on spatial and single nuclei transcriptomics of poor prognosis cancers, please DM me or see me at Lorne. We will be advertising soon. @ozsinglecell.bsky.social #LorneCancer2025 #Lorne2025

ScaleSC: A superfast and scalable single cell RNA-seq data analysis pipeline powered by GPU. https://www.biorxiv.org/content/10.1101/2025.01.28.635256v1

(1/10) Excited to announce our latest work! @arpita-s.bsky.social, @amanpatel100.bsky.social , and I will be presenting DART-Eval, a rigorous suite of evals for DNA Language Models on transcriptional regulatory DNA at #NeurIPS2024. Check it out! arxiv.org/abs/2412.05430

www.nature.com/articles/s41... πŸ’»πŸ§¬

mcRigor: a statistical method to enhance the rigor of metacell partitioning in single-cell data analysis https://www.biorxiv.org/content/10.1101/2024.10.30.621093v1

This is an excellent program, especially for researchers from low-income backgrounds and those who pursue a research career later in life, like me. Thank you for sharing @mehr.nz

Turns out I was relying a bit much on Twitter to keep up with new papers. Any suggestions for how to keep up the latest publications?

πŸ“– New review in Nature Reviews Cancer on how epigenomic heterogeneity drives tumour evolution! We dive into: Check it out if you're into epigenetics, single-cell tech, or the future of cancer therapy! πŸ“– www.nature.com/articles/s41...

As a former general contractor and small business owner before the Great Recession, I found this breakdown logicalβ€”it’s primarily a supply-side issue. But found it lacking, only one presidential candidate wants to deport a significant portion of housing work force. open.spotify.com/show/3IM0lmZ...

πŸ«£πŸ‘€ Deep learning-based predictions of gene perturbation effects do not yet outperform simple linear methods https://www.biorxiv.org/content/10.1101/2024.09.16.613342v1

Evaluating Methods for the Prediction of Cell Type-Specific Enhancers in the Mammalian Cortex https://www.biorxiv.org/content/10.1101/2024.08.21.609075v1 🧬πŸ–₯️ https://github.com/AllenInstitute/EnhancerBenchmark

This is a really great promotion for what I'm sure will be an equally great conference. πŸ’»πŸ§¬ x.com/aepia/status...

Complete genomes for the apes! We have added bonobo, chimp, gorilla 🦍, orangutan 🦧, and gibbon to the T2T family! Lots of very cool stories buried in these genomes, some of which we have explored here, but I expect many more studies to follow: www.biorxiv.org/content/10.1...

Algorithms for a Commons Cell Atlas https://www.biorxiv.org/content/10.1101/2024.03.23.586413v1

Folks I need your help, would you know from where I can buy/collaborate to get zero-mode waveguides to test some of our probes? Wd be gr8ful for a retweet if you dont know the answer.... thank you!

This is an excellent resource and a bit jealous to have not had a module like this offered to me, but will be sharing going forward. Thanks @milesklee.bsky.social

Just checked into X single cell genomics after a few days and saw another person has challenged PCA, the regaining heavy weight champion of dimension reduction since ~1909, to a fight. I wish them well, but my money is on the champ. πŸ’»πŸ§¬

Come be an Eric and Wendy Schmidt postdoc fellow at the Broad in Cambridge MA! For machine learning, stats, applied math PhDs interested in tackling biomedical problems. Considerable independence! Applications reviewed Dec 21 onwards academicjobsonline.org/ajo/jobs/26632