claudiaalcar.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

We have an exciting programme of talks for the ProSE seminars (Protein Structure Evolution). The first session was an inspiring and provocative talk by leader in the field Prof. Andrei Lupas. Next up, 11th March, I'll be speaking about my work on evolution over extremely long time periods.

submitted 6 days ago • 0 comments

🚨 Unravel BILLIONS of years of protein evolution! 🚨 How did protein structures emerge and evolve over deep time? Join @zachary-ardern in the next ProSE Seminar! 📅 March 11, 3PM GMT 🔗 tinyurl.com/prose-seminar2 #ProteinEvolution #StructuralBiology

submitted 2 days ago • 0 comments

📢To all postdocs. Are you ready to start your semi-independent career? The BBSRC Fellowship call is open. We may host you if you work at the interface of DNA replication/chromatin biology/cancer and like to use protein biochemistry, genomics, cryo-EM, AlphaFold, MD... www.ukri.org/opportunity/...

submitted 3 days ago • 0 comments

Sign up for the ProSE Seminars on protein structure evolution. The full program includes talks on deep-time fold divergence, fold switches, and early protein evolution. Next up: @zachary-ardern.bsky.social 📅 March 11, 3PM GMT 🔗 tinyurl.com/prose-seminar2 #ProteinEvolution #StructuralBiology 🧪

submitted 6 days ago • 0 comments

#proteinscience pls join us for this event at AcademiaSinica #Taiwan 🇹🇼!!

submitted 4 days ago • 0 comments

Sign up for the ProSE Seminars on protein structure evolution. The full program includes talks on deep-time fold divergence, fold switches, and early protein evolution. Next up: @zachary-ardern.bsky.social 📅 March 11, 3PM GMT 🔗 tinyurl.com/prose-seminar2 #ProteinEvolution #StructuralBiology 🧪

submitted 6 days ago • 0 comments

🧬 New research reveals that encoded & non-genetic protein variants shape the human proteome in ways previously unknown! These alternative proteoforms expand protein function bypassing genetic constraints. 🔗 Check it!: www.biorxiv.org/content/10.1... #Proteomics #CentralDogma #Translation

submitted 8 days ago • 0 comments

📢 Gender-neutral job ads boost diversity A new study finds that replacing masculine-coded words in job ads increases applications from women and men who do not fit traditional masculine norms. 🔗 www.pnas.org/doi/10.1073/... 🧪 #Inclusion #SciComm

submitted 15 days ago • 1 comment

🧪 Join us today for the first ProSE Seminar on protein structure evolution! Speaker: Andrei Lupas 🕒 3 PM GMT / 4PM CET 🔗 tinyurl.com/prose-seminar1 Don't miss out! #ProteinEvolution #ProSE

submitted 16 days ago • 0 comments

We are closing our X account down on Friday 28 February and will be active on here only from then on. Spread the word and let's get sharing inspiring research and science!

submitted 17 days ago • 2 comments

Together with EMBO, we provide funding for workshops, practical and lecture courses in Brazil, Canada, China, Japan, Mexico and South Korea. 📆 The next application deadline is 1 March 2025. Apply here: https://bit.ly/41hbB47

submitted 17 days ago • 0 comments

Join us for our inaugural #ProSE Seminar, launching a monthly series on Protein Structure Evolution! Speaker: Andrei Lupas (MPI for Biology) Topic: “Highly repetitive genomic ORFs: a source of new fibrous proteins?” When: Feb 11, 3PM GMT, 4PM CET Link: t.co/x5qrQJr4G1

submitted 27 days ago • 1 comment

Announcing the Biophysics Week IDP Trainee Symposium on March 27 at 12pm CT hosted by @idpseminars.bsky.social & The BPS IDP Subgroup! Join via Zoom for talks by talented grad students & postdocs. Abstract submissions are open! See flyer for more details! #BiophysicsWeek @biophysicalsoc.bsky.social

submitted 20 days ago • 1 comment

🔹 SMBE 2025 IDEA Symposium 🔹 @official-smbe.bsky.social We invite abstract submissions for the #SMBE IDEA Symposium to share initiatives that foster a more inclusive and equitable community. 🚨 𝗔𝗯𝘀𝘁𝗿𝗮𝗰𝘁𝘀 𝗱𝘂𝗲 𝗙𝗲𝗯 𝟭𝟱 🔗 Submit your abstract here! ⬇️⬇️⬇️ smbe2025.scimeeting.cn/en/web/index...

submitted 21 days ago • 0 comments

Interested in the emergence and #evolution of protein structures? Join us for the ProSE seminar series starting next week! Co-organized by: @zachary-ardern.bsky.social @lacholt.bsky.social @hassanzaman.bsky.social @caro-rocha.bsky.social & me

submitted 22 days ago • 0 comments

New seminar series! Join us to explore how protein structures evolved! Kicking off with the outstanding work of Andrei Lupas, who revealed how ancient peptides gave rise to modern protein folds ⚗️💫 ProSE launches one day before Darwin's day! 📅 Feb 11, 3PM GMT 🔗https://tinyurl.com/prose-seminar1

submitted 24 days ago • 1 comment

Por favor compartan - eres de México y te gustaría hacer un posdoc en California? Checa esta oportunidad! alianzamx.universityofcalifornia.edu/research-and... Si te interesa aplicar conmigo, con mucho gusto!

submitted 28 days ago • 0 comments

Still one month left to sign up/apply to this PhD course on protein disorder

submitted 26 days ago • 0 comments

🧪 #MEvoSky

submitted 27 days ago • 0 comments

Join the ProSE Seminar Series! A monthly discussion on the #Evolution of #ProteinStructure 🧪 Next up: Andrei Lupas “Highly repetitive genomic ORFs: a source of new fibrous proteins?” 11th February | 3 PM GMT 🔗 Register here: tinyurl.com/prose-seminar1

submitted 29 days ago • 0 comments

We're thrilled to announce the inaugural Protein Structure Evolution (ProSE) Seminar! 🎉 Speaker: Andrei Lupas Topic: "Highly repetitive genomic ORFs: a source of new fibrous proteins?" 📅 February 11, 3PM GMT 🔗 tinyurl.com/prose-seminar1 Please share!

submitted 34 days ago • 1 comment

We're thrilled to announce the inaugural Protein Structure Evolution (ProSE) Seminar! 🎉 Speaker: Andrei Lupas Topic: "Highly repetitive genomic ORFs: a source of new fibrous proteins?" 📅 February 11, 3PM GMT 🔗 tinyurl.com/prose-seminar1 Please share!

submitted 34 days ago • 1 comment

I'm organizing a Keystone symposium, along with Liz Kellogg and @possuhuanglab.bsky.social, on machine learning and macromolecules. Mar 23-26 in Keystone, Colorado. We have a great lineup and deadlines are coming up soon!

submitted 42 days ago • 0 comments

The Royal Society's Newton International Fellowships will open for applications next week on 21 January. These fellowships are for non-UK early career scientists who wish to conduct research in the UK. Find out more on our website: #RSGrants royalsociety.org/grants/newto...

submitted 44 days ago • 3 comments

The Buribushi fellowship, ‘cluster of stars’ in Uchinaaguchi, is now accepting applications to boost outstanding junior researchers, it comes with funding to start a new research group at OIST in the Beautiful Okinawa www.oist.jp/news-center/...

submitted 48 days ago • 0 comments

Two tenure-track positions on computational (www.upf.edu/ca/web/biome...) and quantitative (www.upf.edu/ca/web/biome...) biology at the Medicine and Life Sci. Dept. of @upf.edu. Come and join us to work in the unique environment of @prbb.org at the seafront of Barcelona! Deadline Jan 28. Please RP!!

submitted 50 days ago • 1 comment

I hope this email finds my keys

submitted 513 days ago • 1 comment

Deep learning for proteins tutorial: github.com/Graylab/DL4P...

submitted 61 days ago • 1 comment

I decided to make the datasets I'm generating for my phd project public. For each protein in Swiss-Prot, I'm making available PLM embeddings (ProtTrans, Ankh, ESM2), GO annotations and taxonomy representations. All files follow the same order, one line per protein. github.com/pentalpha/pr...

submitted 62 days ago • 2 comments

Are you a senior PhD student or postdoc? Do you have a cool science story to tell? Do you want to visit Buffalo when the weather is perfect? Then apply for the Emerging Leaders Seminar Series at Roswell Park! DM or email me with questions. (RT please!) www.roswellpark.org/education/pr...

submitted 78 days ago • 0 comments

Noise regulations in North America are generally piecemeal, experts say, and tend to focus on things like parties or concert venues, instead of the sources of noise that actually cause us the most harm: noises from transportation. www.cbc.ca/radio/whitec...

submitted 81 days ago • 5 comments

It’s been 20 years today since my first paper on intrinsically disordered proteins Mapping Long-Range Interactions in α-Synuclein using Spin-Label NMR and Ensemble Molecular Dynamics Simulations doi.org/10.1021/ja04... and I thought I would tell the somewhat random path that led to this paper. 1/n

submitted 68 days ago • 3 comments

About time! And great news for everyone who commutes in central London www.westminstercycling.org.uk/c43-approval

submitted 70 days ago • 0 comments

Reposting this again - We are looking for a postdoc to study the physiology, evolution, and cell biology of anaerobic ciliate-methanogen symbioses using 'omics, experiments, and/or microscopy. Still accepting inquiries, and I would love to hear from interested candidates.

submitted 87 days ago • 1 comment

I've created a new plugin for #PyMOL (called PyMOLfold) that allows you to fold protein sequences right in the GUI. Simply select your model of choice (e.g., #ESM3, Boltz-1) and paste in your amino acid sequence. github.com/colbyford/Py... #ai #proteinfolding #alphafold

submitted 76 days ago • 0 comments

📣 Save the dates 📅 We are organizing a Benzon Symposium on "Protein structure prediction and design" with what I think is an amazing set of speakers Meeting will take place in Copenhagen 🇩🇰 on Sept. 1–4, 2025, and abstract submission will open in March (benzon-foundation.dk/benzon-sympo...)

submitted 76 days ago • 1 comment

Every museum should have a Little Guys Tour, and at the end of the tour you can buy reproductions of all the little guys

submitted 77 days ago • 213 comments

There's still time to register your interest to become the Royal Society's Artist in Residence, an opportunity for a creative individual to produce new work in response to our collections and the scientific research of our community. Express your interest here: royalsociety.org/about-us/wor...

submitted 79 days ago • 1 comment

As Lorne Protein Meeting approaches its 50th anniversary we’re excited to welcome the fantastic speakers coming in 2025 to celebrate. www.lorneproteins.org/speakers2025

submitted 93 days ago • 16 comments

Klára Hlouchová from the Department of Cell Biology received an ERC Consolidator grant!👋 A groundbreaking ERC-funded project aims to create 'LIFE-19'—a bacterial strain using just 19 amino acids instead of 20 🧬. Congratulations! #SyntheticBiology #ERCCoG 📌 1url.cz/U1Zvc

submitted 86 days ago • 0 comments

I just tried this and it worked the first time with no setup fuss or dependency annoyances or anything, just did exactly what the docs said it would do. That's so rare I have to celebrate it!

submitted 84 days ago • 1 comment

Very cool work from Yang Lu et al. demonstrating miscalibration of BLASTP’s E-values and generating well-calibrated values via a knockoff-based approach (cc @mikelove.bsky.social) - academic.oup.com/bioinformati...! More analyses could benefit from knockoff-based approaches.

submitted 85 days ago • 2 comments

CAPRI conclusions from the CASP16 assembly session

submitted 87 days ago • 0 comments

For those around Zurich, I'll be at the Zurich Seminar in #Bioinformatics this Thursday to talk about my work on the impact of phosphorylation on protein structure: compbiozurich.org/news/2024/20...

submitted 86 days ago • 1 comment

Registration is OPEN for the Gordon Research Conference on #Microproteins! Scholarships are available. Get involved now while spaces are still available. You won't want to miss this! 🧪 🧬 💻 🔎 microproteins #darkgenome #NoncodingGenome #Cancer #Proteomics #sORFs #Ribose www.grc.org/decoding-mic...

submitted 90 days ago • 2 comments

We did this crazy project where we tried to see if proteins could interact with their mirror image ligand. Seems impossible when proteins need to form 3D structures to interact. But what about if the interaction remains disordered??? www.nature.com/articles/s41...

submitted 91 days ago • 8 comments

Hi Bkuesky! I’m a group leader training generative models for protein design. I dream of agentic solutions for enzyme design, where models autonomously take decisions and iteratively learn from experimentally feedback. I’m happy to be back to a social network to actually read science!

submitted 92 days ago • 1 comment