clementsui.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

🚨 Applications Open! 🎓 The Master 2 EvoGEM offers training in computational & mathematical modelling to interpret evolutionary mechanisms from genomic data. 📍Taught in English in Paris (MNHN, PSL, Sorbonne Univ., Univ. Paris-Cité & Paris-Saclay) 🔹 Research in leading labs 🔗 Apply now: evogem.fr

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Happy to share our latest preprint on environmental reservoirs of antimicrobial resistance #AMR www.biorxiv.org/content/10.1...

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Excellent review! Cryptococcal nutrient acquisition and pathogenesis: dining on the host | Microbiology and Molecular Biology Reviews journals.asm.org/doi/10.1128/...

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🚨 new preprint 🚨 Here we report that deleting the Septin aspB results in cidal activity of the static anti cell wall drug Caspofungin. This wasn’t only in vitro as 🐭 infected with the mutant and treated had 70% survival compared to 30% of the wild-type 1/2

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Context matters: assessing the impacts of genomic background and ecology on microbial biosynthetic gene cluster evolution #mSystems MiniReview by by @raufs.bsky.social & @lkalan.bsky.social journals.asm.org/doi/10.1128/...

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📢Emerging & re-emerging infections among migrants 📆18 March Join this webinar on #respiratory infectious diseases in #refugees, providing insight into the epidemiology, prevention &management of important #pathogens tinyurl.com/55hdjkb6 @souhakanj.bsky.social @heiman-wertheim.bsky.social

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The diagnosis of mucormycosis by PCR in patients at risk: a systematic... www.sciencedirect.com/science/arti...

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#Genomic investigations of successful invasions: the picture emerging from recent studies #evolution #ecology onlinelibrary.wiley.com/doi/10.1111/...

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Our Opinion on the balance between horizontal and vertical transmission in plasmids and phages is up and looking pretty at Trends in Microbiology! Work with Andrina Bernhard and @claudiaigler.bsky.social

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New online! The role of bacterial metabolism in antimicrobial resistance

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Soil microbiome bacteria protect plants against filamentous fungal infections via intercellular contacts | PNAS www.pnas.org/doi/10.1073/...

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And the new 🦇🦇🦇 assemblies keep coming, this time from #HuabinZaho lab, out last week in @natureecoevo.bsky.social www.nature.com/articles/s41...

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Landmark paper claxon! 'Evaluating the economic and health impact of proactive genomic epidemiology in a hospital setting' www.medrxiv.org/content/10.1... Significant savings associated with proactive genomic epidemiology.

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rdcu.be/d97Ex

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rdcu.be/d91Zt #Fungal biofilms in human health and disease #medical #mycology

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Evolution takes multiple paths to evolvability when facing environmental change | PNAS www.pnas.org/doi/abs/10.1...

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Diabetes potentiates the emergence and expansion of antibiotic resistance | Science Advances www.science.org/doi/10.1126/...

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Kodamaea ohmeri: an emergent #yeast from a one health perspective www.sciencedirect.com/science/arti...

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#Evolution #ecology The Idiot's Guide to Effective Population Size onlinelibrary.wiley.com/doi/10.1111/...

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Antibody responses in Klebsiella pneumoniae bloodstream infection: a prospective cohort study - The Lancet Microbe www.thelancet.com/journals/lan...

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Very interesting! Azole resistant #Candida auris in locusts. www.biorxiv.org/content/10.1...

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www.biorxiv.org/content/10.1...

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Delimiting #Species — Prospects and Challenges for DNA #Barcoding onlinelibrary.wiley.com/doi/10.1111/...

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Rapid and dynamic evolution of a giant Y chromosome in Silene latifolia | Science www.science.org/doi/10.1126/...

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Varied prevalence and asymptomatic carriage of Cryptococcus gattii in the gut of Chinese populations - The Lancet Microbe www.thelancet.com/journals/lan...

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rdcu.be/d84sh when the same dataset tells a different story…

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Unprecedented Number of Recurrent Mutations Drive the Rapid Evolution of Pesticide Resistance in a Notorious Pest https://www.biorxiv.org/content/10.1101/2025.02.06.636798v1

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New preprint! How much does antibiotic use shape bacterial lineage dynamics, and how does that relate to the fitness costs/benefits of resistance determinants? All sorts of fun findings and a method that we hope will be broadly useful. See @dhelekal.bsky.social's thread and the preprint!

submitted 19 days ago • 1 comment

Lu et al. used pool-seq to identify candidate genes linked to resistance to Dothistroma needle blight in lodgepole pine, jack pine, and hybrids. These results can aid forest management and resistance breeding. doi.org/10.1111/eva.70078 Photo: Robert L. James/U.S. Forest Service (CC BY)

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Sexual recombination in cereal rust #fungi: Knowns and unknowns of pathogen evolution and adaptation journals.plos.org/plospathogen... #sex #evolution

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rdcu.be/d8MsK

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Julian was the tower in @UBC Microbiology. I still remember our conversation, his wisdom and kindness.

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Let's see if Bluesky has some magic ... Is there a way to plot a dated phylogeny with a log-scale time axis? If possible, using R 🧪 #EvolSky #ecoevo @phylogeny.bsky.social #phylo #rstats #plantscience botany

submitted 22 days ago • 4 comments

Widespread use of azole fungicides in agriculture may reduce the effectiveness of antifungal treatments for patients with aspergillosis. EMA highlights that nearly all 120,000 tonnes of azoles sold in the EU were used as pesticides, potentially contributing to #AMR www.ema.europa.eu/en/news/one-...

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Mutation ages and population origins inferred from genomes in structured populations https://www.biorxiv.org/content/10.1101/2025.01.28.635333v1

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Our latest Pearl, "Decoding Cryptococcus: From African biodiversity to worldwide prevalence," is now in PLOS Pathogens! We reflect on how biogeography, genetic diversity, and ecological factors shape global distribution, with a special focus on African biodiversity. journals.plos.org/plospathogen...

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Setting new boundaries of 16S rRNA gene identity for prokaryotic taxonomy www.biorxiv.org/content/10.1... #jcampubs

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De-biasing microbiome sequencing data: bacterial morphology-based correction of extraction bias and correlates of chimera formation microbiomejournal.biomedcentral.com/articles/10.... #jcampubs

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"Immediate action is essential to control... infections that are becoming increasingly difficult to treat." ECDC warns that rising carbapenem-resistant Enterobacterales (CRE) poses a significant threat to European patients and healthcare systems. www.ecdc.europa.eu/en/news-even...

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Laboratory adaptive evolution of thermotolerance is linked to the evolution of a robust proteostasis in S. cerevisiae https://www.biorxiv.org/content/10.1101/2025.01.31.635942v1

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Warmer climates could supercharge fungal diseases transmitted by insects. pubmed.ncbi.nlm.nih.gov/39907444/

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#yeast #popgen onlinelibrary.wiley.com/doi/full/10....

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Comparative transcriptional analysis reveals gene expression changes in spore germination of opportunistic pathogenic fungi https://www.biorxiv.org/content/10.1101/2025.02.03.636182v1

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Candidate transmission survival genome of Mycobacterium tuberculosis https://www.biorxiv.org/content/10.1101/2025.01.30.635747v1

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Disperazol Pharma joins the AMR Industry Alliance to combat #AMR by targeting biofilms and supporting biotech innovation. Their approach enhances drug efficacy through advanced delivery methods like nanoparticles, targeted therapies, and AI-driven optimization. karacasanime.com.ve/uncategorize...

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How does a 🍄 genome change in evolutionary transition to life on another 🍄 ? Congrats @ccgallen.bsky.social on first results on this strange Sporothrix we started studying during the pandemic. TLDR: +-1/3 of genome lost in switch to life in matrix of another fungus, but intriguing CAZymes gained

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Conjugative Plasmids Rarely Confer Antibiotic Resistance or Virulence https://www.biorxiv.org/content/10.1101/2025.01.30.635773v1

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Genetic differentiation in the MAT-proximal region is not sufficient for suppressing recombination in Podospora anserina academic.oup.com/g3journal/ar...

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Survival and Spread of Engineered Mycobacterium smegmatis and Associated Mycobacteriophage in Soil Microcosms https://www.biorxiv.org/content/10.1101/2025.01.27.635130v1

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