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colby.tuple.xyz
Computational Biologist & Cloud AI Architect. 2X Microsoft MVP Awardee in AI and Azure. Currently at Tuple and UNC Charlotte's CIPHER center. 🧬 https://colbyford.com | https://tuple.xyz
12 posts 47 followers 6 following
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Posts 12 Comments 1

H5N1 Adapts for a Human Host youtu.be/FNWdzaZCemk?... via @YouTube

submitted 3 days ago • 0 comments

New paper: #AI -Based #Antibody Design Targeting Recent #H5N1 Avian Influenza Strains www.biorxiv.org/content/10.1...

submitted 43 days ago • 0 comments

New avian #influenza (H5N1) paper: Large-scale computational modelling of H5 influenza variants against HA1-neutralising antibodies! We used #AI- and #physics-based modeling of over 18k H5N1 isolates. Paper: lnkd.in/ekikJrE9 Code: lnkd.in/eY8Y4vmt #bioinformatics #genomics #computationalbiology

submitted 79 days ago • 0 comments

New paper! Transcriptomic analyses in bioinformatics are only as good as the data we give them. In this article, we outline some best practices for QC in sequencing and bioinformatics in RNA-seq, scRNA-seq, ATAC-seq, ChIP-seq, and a ton more. Read the article: www.sciencedirect.com/science/arti...

submitted 125 days ago • 0 comments

I've created a new plugin for #PyMOL (called PyMOLfold) that allows you to fold protein sequences right in the GUI. Simply select your model of choice (e.g., #ESM3, Boltz-1) and paste in your amino acid sequence. github.com/colbyford/Py... #ai #proteinfolding #alphafold

submitted 176 days ago • 0 comments

New Paper Alert! We're very excited that our SARS-CoV-2 N <> cytokine modeling paper has been accepted in Frontiers in Bioinformatics. In this work, we showcase the use of high-performance computing for large-scale molecular modeling. Give it a read: www.frontiersin.org/articles/10....

submitted 371 days ago • 0 comments

Our consortium paper for CAGI: The Critical Assessment of Genome Interpretation was just released. Read the paper in Genome Biology here: genomebiology.biomedcentral.com/articles/10.... #bioinformatics #genomics #genetics #computationalbiology #machinelearning #ai #datascience #rarediseases

submitted 468 days ago • 0 comments

I'm very excited to present some exciting research that I've been working on. PD-1 is a very important target in cancer therapeutics, so using AI to speed up the drug discovery process is certainly of interest. AI-designed anti-PD-1 antibodies - bioRvix preprint (www.biorxiv.org/content/10.1...)

submitted 500 days ago • 0 comments

I'm very excited to share this collaborative research project that included myself and researchers from MIT Lincoln Lab where we showcased the utility of high-performance computing to scale molecular modeling in SARS-CoV-2 research. Read the preprint here: www.biorxiv.org/content/10.1...

submitted 551 days ago • 0 comments

Protein Sequence Generation with EvoDiff: colbyford.medium.com/exploring-ai... #proteins #diffusion #ai #computationalbiology #bioinformatics #rfdiffusion #alphafold #colabfold

submitted 601 days ago • 0 comments

Hello, BlueSky. ☁️

submitted 601 days ago • 1 comment

Behavioral and transcriptomic analyses of mecp2 function in zebrafish https://www.biorxiv.org/content/10.1101/2023.09.13.557635v1

submitted 630 days ago • 0 comments