csconn-phd.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

Oooo pretty new MassSpec data coming in (only slightly hung-up on the 1/78 samples that wasn't perfect lol)

submitted 30 days ago • 1 comment

Looking forward to sharing our research @rutgersupress.bsky.social tomorrow @12 Nelson D406

submitted 38 days ago • 0 comments

Excited to share our review article "Finding functional microproteins", published in @TrendsGenetics. It was fun writing it together with Alex and @FeiyueYang1 in the lab. #microprotein authors.elsevier.com/a/1kNCscQbJB...

submitted 59 days ago • 1 comment

Excited to share our @cp-trendsgenetics.bsky.social Spotlight Article highlighting the development of #ribo-seq by @nickingolia.bsky.social and how it has revolutionized the study of #microproteins! www.sciencedirect.com/science/arti...

submitted 48 days ago • 1 comment

Time to share our organelle proteome paper out in @cellcellpress.bsky.social: doi.org/nzwz We created a spatial map of human cells using organelle immunoprecipitation at scale. Locate your fav protein among the 7,600 we mapped across 19 subcellular compartments: organelles.sf.czbiohub.org/ 1/3 🧪

submitted 48 days ago • 7 comments

If you had any question that microproteins / micropeptides are the next wave in #cancer 🌊 Well this is the paper that you need to read. 🔎 microproteins 🧬 💻 #RNAsky #genomics #bioinformatics www.biorxiv.org/content/10.1...

submitted 51 days ago • 1 comment

The first preprint of 2025! Together with Matvei, @halfacrocodile.bsky.social, & our amazing team, we are excited to share PARADE: an AI framework for designing mRNA UTRs with enhanced cell-type specificity & stability. www.biorxiv.org/content/10.1...

submitted 60 days ago • 1 comment

Congratulations to @fendtlab.bsky.social amd @ginevradoglioni.bsky.social for this massive work "Aspartate signalling drives lung metastasis via alternative translation" www.nature.com/articles/s41...

submitted 60 days ago • 2 comments

Great work from Gloria Brar’s group on the role of paralogous RNA helicases in the heat shock response. Surprising increase in growth at high temperature and impact of a short motif! Also important implications of the role of biomolecular condensation. Awesome www.cell.com/cell-reports...

submitted 75 days ago • 0 comments

Direct RNA sequencing is featured as one of The Scientist 2024 Top 10 Innovations. Read to find out how the latest direct RNA #nanopore sequencing kit and flow cell has improved accuracy and output, enabling a more complete picture of the landscape of RNA Read: www.the-scientist.com/2024-top-10-...

submitted 75 days ago • 0 comments

What is the best distance-adjusting, multi-channel to go from Eppendorf 1.5/2mL tubes to 96-well plate format?

submitted 76 days ago • 2 comments

Our latest work is out in Nature today! Using smFRET, we directly visualized recruitment of the eIF4F complex to the 5' cap of eukaryotic mRNAs and formation of an activated mRNA. Our findings reveal new and surprising roles for each eIF4F component. 1/3 www.nature.com/articles/s41...

submitted 81 days ago • 11 comments

Applications for our SUPERS 2025 Summer Internship open today! Share with undergraduates you know interested in learning/studying translational medicine from Cancer Bio, Radiobiology & Imaging, to Medical Physics med.upenn.edu/supers/

submitted 81 days ago • 0 comments

@themodzlab.bsky.social worlds colliding ;)

submitted 81 days ago • 0 comments

Look forward to reading this in full!

submitted 81 days ago • 0 comments

SPATIAL PROTEOMICS is the Method of the Year 2024!!! 🤩🤩🤩 www.nature.com/articles/s41...

submitted 86 days ago • 1 comment

Excited to reveal specific reactive oxygen species as sentinel molecules that control localized protein degradation at #mitochondria to adjust electron transport chain abundance, with many implications for the role of ROS in development and disease. www.cell.com/molecular-ce...

submitted 87 days ago • 6 comments

Looking forward to enjoying the full taste of RNA! www.embl.org/about/info/c...

submitted 91 days ago • 0 comments

Are you a scientist working or interested in RNA Translation? Join our starter pack and share ideas, methodologies and tips to advance our knowledge in how life came to be! #RNA #ribosome go.bsky.app/VN78eTo

submitted 98 days ago • 39 comments

The conserved landscape of RNA modifications and transcript diversity across mammalian evolution https://www.biorxiv.org/content/10.1101/2024.11.24.624934v1

submitted 98 days ago • 0 comments

Awesome new work on tRNAs and staibilty! Check it out: www.science.org/doi/10.1126/...

submitted 101 days ago • 0 comments

endorse, and supported by data from Hannah Toutkoushian in her dissertation. glad to see more about eIF2A escholarship.org/uc/item/6pr6...

submitted 102 days ago • 0 comments

#DarkGenome #NoncodingGenome fanatics - this one is for you. 👇 🧬 💻 🧪 #genomics #bioinformatics

submitted 103 days ago • 0 comments

Fellow #RNA lovers, please repost 🙏: 2 ERC-funded Post-doc positions are available in our lab to investigate #RNA structural ensemble and their dynamics in living cells. Application link: t.co/pYJ3H3j705

submitted 107 days ago • 0 comments

If you are interested in #RNA regulation, translational control, cancer progression, and/or therapy resistance... (+cookies&Shenanigans): The Conn Lab is #Hiring for Postdoc and senior research positions @PennMedicine full description: rnasociety.memberclicks.net/postdoc-and-...

submitted 107 days ago • 0 comments

Happy to welcome three Summer Undergraduate Scholars to the lab this Summer: Vinny Dong (PURM), Keiko Luke (SUPERS), and Hemanta Adhikari (PURM). Exited to see & share the discoveries they will make on mRNA selection in response to prostate cancer therapy! csconnlab.com/team

submitted 262 days ago • 0 comments

Looking forward to seeing Andrew Hsieh tonight and hearing about some of their lab's fantastic research tomorrow. It's been too long :) Come join us in Smilow @12 (lunch included) to learn more about how RNA is awesome!

submitted 312 days ago • 0 comments

Happy Spring to all! Quick Conn Lab updates: Ian received the NSF & Ashley will be attending Penn CancerBio for PhD program :) I'm also truly honored to have received the 2024 Michael P. Nusbaum Graduate Student Mentoring Award. Grateful for such spectacular Mentees!

submitted 319 days ago • 0 comments

Happy New Year from the Conn Lab! Celebrated with great company and gift exchange/heisting ;) Great year growing the team, collaborations, and moving along lots of new research. Best wishes to all for 2024! #RNAisAwesome #ConnLabShenanigans

submitted 426 days ago • 1 comment

Spurred on by ribosome profiling and other cool methods, translation elongation has grown into a whole field with new surprises all the time (and new relevance for vaccine mRNAs!). Here’s our latest on why synonymous codons aren’t all the same. (Thread) www.biorxiv.org/content/10.1...

submitted 460 days ago • 1 comment

We are looking for housekeeping genes (meaning ubiquitously expressed across tissues) that only exist in mouse or human (no ortholog). Anybody know some examples?

submitted 468 days ago • 4 comments

Embracing Fall together... apple picking, picking, corn maze, bonfires and #connlabshenanigans

submitted 495 days ago • 0 comments