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davisjmcc.bsky.social
Head, Bioinformatics and Cellular Genomics Lab, St Vincent's Institute of Medical Research, Melbourne. Stats, AI/ML, bioinformatics, genomics, single-cell. https://www.svi.edu.au/researchers/dr-davis-mccarthy/
15 posts 1,578 followers 473 following
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📢 Thrilled to see this out, an atlas of e/sQTL across multiple tissues and diverse ancestries in 14,324 TOPMed participants: www.medrxiv.org/content/10.1... Grateful to the #TOPMed #Omics WG for giving me an opportunity to learn and contribute to this important work 🧬

submitted 1 day ago • 1 comment

📣 Registrations and Abstract submissions are now open for Cancer Bioinformatics Australia 2025! Abstracts, due 11th April: cancerbioinformatics.au/abstracts Registration: cancerbioinformatics.au/register Further info: cancerbioinformatics.au See flyer for our amazing invited speakers!

submitted 2 days ago • 0 comments

Our new paper examining how to analyse longread RNA-seq with no reference genome. We compare approaches for assembly and downstream analysis, from transcript accuracy to differential expression. Lead by @alexyfyf.bsky.social. Thnx to all contributors incl. @qgouil.bsky.social for the pea data!

submitted 17 days ago • 1 comment

WOW!! 🤩 Congrats to Banovich et al. on the LARGEST imaging-based spatial transcriptomic study of the human lung to date! This study discovers conserved spatial pathological signatures and alveolar remodeling in pulmonary fibrosis disease progression.

submitted 21 days ago • 0 comments

Excited to post my first #skySplain about our recent work published yesterday in Nature Genetics! www.nature.com/articles/s41.... One of the first authors of this study - Annika Vannan – actually wrote this breakdown, but she's not yet over here on bluesky and asked me to post!

submitted 23 days ago • 3 comments

Many thanks to my supervisors @davisjmcc.bsky.social and Heejung who encouraged me to write this piece up! It is not a style of writing that I am the most familiar with so it took a lot of experimenting and also valuable feedback from @jeffreypullin.bsky.social on some earlier versions

submitted 78 days ago • 0 comments

Have you been thinking hard about statistical modelling of scATAC-seq data? (No.) Luckily for you, @aaronkwc.bsky.social has! Aaron will help you grok: What's going on? What is TF-IDF? Is there really single-cell level chromatin information? Check it out 👇 www.biorxiv.org/content/10.1... 🧪🧬💻

submitted 79 days ago • 2 comments

Now new and improved and out on Genome Medicine! link.springer.com/article/10.1...

submitted 79 days ago • 4 comments

A commonly inherited genetic variant of human PCSK9 drives breast cancer metastasis and associates with reduced patient survival in @cellcellpress.bsky.social PCSK9 drives pro-metastatic gene expression by repressing LRP1. Anti-PCSK9 antibody suppresses Br mets. sciencedirect.com/science/arti...

submitted 79 days ago • 0 comments

We've been doing this for a few years - except we call them "one minute updates" (actual time may be 30s to 5+ mins) and just go round the table It's been great and would wholeheartedly recommend - I didn't know about the "flashlight" concept/version of this until now

submitted 85 days ago • 0 comments

One year ago we started a new experiment in the lab - not a scientific one, but a social one! We now use the 'flashlight' 🔦 at the start of every lab meeting ⏬ Its been great to hear from so many people who love it too - maybe try it out for your group also? 🧪⚕️🩺 www.nature.com/articles/d41...

submitted 175 days ago • 0 comments

QC of scRNA-seq data matters as much (more?) now than it did in 2015 Considering nuclei-free cells makes a lot of sense

submitted 85 days ago • 0 comments

📢 World-leading Immunologists. The Nossal Endowed Chair of Immunology has just been announced @wehi-research.bsky.social. This is your chance to move (or return) to Australia to do ground-breaking research and join a thriving environment for discovery and translation.

submitted 87 days ago • 0 comments

Happy to see our Damsel @bioconductor.bsky.social package published in Bioinformatics. Great work putting together this DamID sequencing and package from student Caitlin Page. Thanks to collaborators too @lonsbio.bsky.social academic.oup.com/bioinformati...

submitted 90 days ago • 0 comments

We’ve put up summary statistics for over 3,000 traits in the All of Us resource, and a shiny new browser alongside it! Explore your favorite gene or phenotype here: allbyall.researchallofus.org #ASHG24

submitted 110 days ago • 1 comment

We're BACK, baby! Blue sky time? SCIENCE time! youtube.com/shorts/MncBv...

submitted 97 days ago • 0 comments

We have a new position for a bioinformatician / computational biologist exploring genomic and epigenomic features of #cfDNA to uncover new cancer biology. careers.petermac.org/job/MELBOURN...

submitted 98 days ago • 0 comments

🚨🚨Blue sky intro thread🚨🚨 Excited to rekindle the old #scitwitter vibes and have a fun platform to share and discuss our work! My lab (banovichlab.org) studies how genetic variation modulates gene regulation and how gene regulatory changes drive disease processes 1/N #scisky #skysci

submitted 105 days ago • 1 comment

I’m looking to recruit PhD candidates to work with me at Flinders University in #Bioinformatics. Details at the link below 👇 Please share to your networks! www.flinders.edu.au/scholarships...

submitted 106 days ago • 1 comment

There are so many people moving over that I'm sure I'm missing folks. Can we make a #compbio / #genomics intro thread to get reacquainted? I'm at the University of Colorado. I often say that if you pick two of three from #transcriptome, #ML, and #publicdata, my lab is probably interested.

submitted 106 days ago • 50 comments

I made a starter pack for algorithmic genomics. It's certainly incomplete, but already has a ton of awesome peeps. Let me know if you know people I should add (with a focus on algorithms and data structures in genomics) go.bsky.app/TRWCnZs

submitted 107 days ago • 25 comments