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dewitlab.bsky.social
Computational & Genomics Lab studying 3D genome function and dynamics @ Netherlands Cancer Institute
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One week left!! Here is a reminder that Institut Pasteur launched an International call to recruit top young researchers. Diversity, Equity, Inclusion, and improving health for people worldwide are among our top priorities. Come join our international community of passionnate and driven scientists.

Single molecules, in living zebrafish embryos, during hour-long period of development: Jonas' work on binding kinetics of cohesin and CTCF around ZGA now online. Great collab with labs of @lucagiorgetti.bsky.social @akispapantonis.bsky.social doi.org/10.1038/s414...

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Two more weeks to apply to join us in Paris ! research.pasteur.fr/en/call/call...

Is your job, or the job of someone you know, mostly funded by indirect costs on NIH grants? If so, I’d love to chat with you for a story in @ScienceNews.bsky.social. You can DM me or email me at aviveros [at] sciencenews [dot] org. #MedSky #ChemSky

Excited to announce that the EMBO workshop on Enhancer Mechanics and Enhanceropathies, June 16-20, 2025, Hindsgavl Castle, Middelfart, Denmark, is now open for registration and abstract submission. !! SAVE THE DATE and register soon !! 👇 meetings.embo.org/event/25-enh... #EMBO #enhancer

The lab is looking to hire a postdoc or senior research associate to work on transcription factors. Any aspect of transcription factors or mechanisms of transcription regulation. The position is fully funded by my NIH R35 until Dec 2028, unless NIH implodes. email me!

3 great computational positions available at @alloxbio.bsky.social to work with the great @ajfaure.bsky.social @juliadiumenge.bsky.social and team

Don’t forget to apply! This is an amazing opportunity!

EMBO Workshop – DNA topology and topoisomerases in genome dynamics. 15-19 September 2025 Szklarska Poręba, Poland REGISTRATION NOW OPEN Interested in attending? Visit the website: meetings.embo.org/event/25-dna... Register by: 15 March 2025

Why do cells respond differently to the same perturbations, even if they are isogenic? Turns out that cell-state affects information flow through the intracellular signaling networks, which can affect the treatment response. New preprint with the lab of Klaas Mulder www.biorxiv.org/content/10.1...

Together with @smandrup.bsky.social and Minna Kaikkonen we are happy to announce the 3rd Edition of the EMBO Workshop on #Enhancers and #Enhanceropathies. This time we will meet during the beautiful Danish summer (June 16-21). Book the dates and register soon!!! meetings.embo.org/event/25-enh...

The EMBL Epigenetics and Neurobiology Unit in Rome is hiring a Group Leader to work on Molecular Mechanisms of Environmental Adaptation. This is a fantastic opportunity, please repost! embl.wd103.myworkdayjobs.com/EMBL/job/Rom...

🌟 Spots are limited—register now! 🌟 Join us for the 2025 Cancer Genetics and Epigenetics GRC in Tuscany, Italy, May 18–23, where global experts will present their latest breakthroughs and discuss the future of cancer research. Register today: www.grc.org/cancer-genet...

#Jobs We are looking for a new colleague! Tenure Track Assistant Professor in Biophysics in the domains of functional imaging and biophysics. More info here: www.wur.nl/en/vacancy/a...

This Friday! Job Dekker, PhD presents the Monthly Seminar on Physical Genomics: Mechanisms of Chromosome Folding January 31, 2025 - Live on Zoom @ 12pm CT - Registration is free at tinyurl.com/5n6ep25m #chromatin #genomics #northwestern #research #dna #umass #biophysics #epigenetics #biology

1/ Pleased to share our review, published today @natrevimmunol.bsky.social, highlighting how biomolecular condensates enhance the precision and flexibility of gene regulatory networks that guide fate decisions during normal and pathological immune cell development. www.nature.com/articles/s41...

Three-dimensional organization of amoeba Dictyostelium discoideum has fascinating features! Very prominent dots at between convergent gene positions, something never really seen for other species. More about the puzzle and how the team of my PhD colleagues resolves it: doi.org/10.1093/nar/...

The Institute for Integrative Biology of the Cell (I2BC) is recruiting group leaders in cell biology. Don't miss the opportunity to start your team in the vibrant environment of Paris-Saclay University. Application deadline: Feb 28, 2025 www.i2bc.paris-saclay.fr @i2bcparissaclay.bsky.social

Hear, hear! The Universtiy Medical Center Goettingen is inviting applications to its new Medical Scientist Program “Genomic responses to disease plasticity” funded by the EKF Stiftung. The program will support early-career bioscientists with a PhD eager to do clinically-oriented research... 1/n

Amid concerning times, sharing a bit of positivity: our 1st preprint of 2025 (funded VIA NIH COMMON FUND), heroically led by Marty Yang (@martyyang.bsky.social) w/ huge assist from @genophoria.bsky.social lab. Lots to cover so let’s get this tweetorial started (1/n)! www.biorxiv.org/content/10.1...

jobs.utoronto.ca/job/Assistan...

Very excited to share our paper on Gene and Transposable Element expression in mammalian preimplantation development, online today! www.cell.com/cell/fulltex... A short thread to highlight some of our findings 🧵

Come join us for this very first conference on single molecule approaches (both omics et imaging) to understand gene expression regulation. Lots of slots for young selected speakers!

Exciting news 📃🧬🔬 Today we report on the dynamics of a fascinating class of molecular motors, so-called SMC proteins in @cp-cell.bsky.social doi.org/10.1016/j.ce...

Excited to share James Jusuf's preprint: By integrating Micro-C with SuperRes Live-Imaging we can calibrate genomics&imaging to perform absolute quantification of looping (e.g. this loop is present 3%) We quantify mESC 36k loops: <loops> are generally rare (2.3%) www.biorxiv.org/content/10.1...

### Job alert, please repost! ### We're recruiting a computational postdoc in evolutionary genetics to help us understand whether recently emerged ncORFs and microproteins play roles in childhood brain cancers. Will you become part of our team? werkenbijprinsesmaximacentrum.nl/en/vacancy/p...

We have open PhD positions! Application is now open. Apply to our and other NKI groups via the NKI PhD program at bit.ly/3O4bOjq

📢 Save the date! We are excited to announce the International Dutch Embryo Model Meeting 2025 in Nijmegen (NL) on Thursday 27 March and Friday 28 March! Registration is open now. More information: ru.nl/en/about-us/... Big thanks to Hendrik Marks for taking the lead this time!

We are still waiting for applications to join us as a group leader in the department of Chromosome Biology! Apply until the first of Feb.

Excited to share @domenicnarducci.bsky.social 's paper now out in Mol Cell published back-to-back with the paper from @dewitlab.bsky.social‬ - despite lots of prior work, we find that ZNF143 has no looping function www.sciencedirect.com/science/arti... www.sciencedirect.com/science/arti...

Please check out our new paper showing that the supposed looping factor ZNF143 has no role in chromatin looping: www.cell.com/molecular-ce... And also check out the companion paper from @andersshansen.bsky.social: www.cell.com/molecular-ce...

Just obtained your Science Master's degree? Turn your knowledge into breakthroughs with the NKI #PhD Program. Dive deep into cancer research, enjoy weekly lectures of renowned scientists & be part of a vibrant international community. Apply as of Jan 1 ➡️ t.co/Ln7xs1zphE

📣 Please share: We’re hiring a tenure-track Group Leader in Multicellular Systems to explore the molecular and cellular mechanisms driving the formation, maintenance, or destabilization of tissues, organs and organisms. Apply at: www.fmi.ch/education-ca...