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dijiang319.bsky.social
Senior editor @science.org. Molecular biology, #DNA, #RNA, #gene regulation, #epigenetics, nuclear biology, #chromatin biology, 3D #genome, #synbio, #CRISPR and gene editing, other bacterial immune systems, and #AI in all these
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there is a podcast about #phage, but not a phage emoji #PhageSky #virology #microbiology

🧬🧫🦠 @science.org Bacterial reverse transcriptase synthesizes long poly-A–rich cDNA for antiphage defense | Science www.science.org/doi/10.1126/... #microbiology #bacteriophage #antiphage #immunity #DNA #RNAsky #RT #Cryo-EM #DRT9

🐛🕷️🕸️ @science.org Hawaiian caterpillar patrols spiderwebs camouflaged in insect prey’s body parts | Science www.science.org/doi/10.1126/... #entomology

🧬🦠🧫 @science.org RNA-mediated CRISPR-Cas13 inhibition through crRNA structural mimicry | Science www.science.org/doi/10.1126/... meeskelab.org bit.ly/sustecheducnJiaLab #CRISPR #RNA

🧬@science.org Structural basis for nucleolin recognition of MYC promoter G-quadruplex | Science www.science.org/doi/10.1126/... @cancer-inst-purdue.bsky.social danzhou-yang.com #DNA #StructuralBiology

🧬 @science.org Rules of engagement for condensins and cohesins guide mitotic chromosome formation | Science www.science.org/doi/10.1126/... @edinburgh-uni.bsky.social @golobor.bsky.social @imbavienna.bsky.social @jobdekker.bsky.social @umasspress.bsky.social @hhmi.org @mitofficial.bsky.social et al.

🩸 @science.org Transcription factor networks disproportionately enrich for heritability of blood cell phenotypes | Science www.science.org/doi/10.1126/... @bostonchildrens.bsky.social @danafarber.bsky.social @harvardmed.bsky.social @hhmi.org @broadinstitute.org

🧬 @science.org Exogenous RNA surveillance by proton-sensing TRIM25 | Science www.science.org/doi/10.1126/...

🦠🧫 @science.org Cat1 forms filament networks to degrade NAD+ during the type III CRISPR-Cas antiviral response | Science www.science.org/doi/10.1126/... @christianfbaca.bsky.social @rockefelleruniv.bsky.social @hhmi.org @mskcancercenter.bsky.social

🧬 @science.org Structural insights into chromatin remodeling by ISWI during active ATP hydrolysis | Science www.science.org/doi/10.1126/...

🦋🐝🐞🐜🦗🦟🪰🪲🪳

👴 💨⛸️🧊👍 At 95, He’s the World’s Oldest Speedskater. He’s Gunning for 100. www.nytimes.com/2025/03/16/w...

@science.org Cryo-EM reveals mechanisms of natural RNA multivalency | Science www.science.org/doi/10.1126/... #RNAsky #RNAbiology #Cryo-EM

Also @science.org Rapid butterfly declines across the United States during the 21st century | Science www.science.org/doi/10.1126/...

@science.org A subcellular map of translational machinery composition and regulation at the single-molecule level | Science www.science.org/doi/10.1126/...

@science.org G-quadruplex–stalled eukaryotic replisome structure reveals helical inchworm DNA translocation | Science www.science.org/doi/10.1126/... @sahilbatra.bsky.social @benallwein.bsky.social @dirkremus.bsky.social www.mskcc.org/research/ski...

@science.org Structural mechanism of LINE-1 target-primed reverse transcription | Science www.science.org/doi/10.1126/... @automnenine.bsky.social @kellythd-nguyen.bsky.social ghanim.lab.princeton.edu www2.mrc-lmb.cam.ac.uk/groups/nguyen/

@science.org Telomeric transposons are pervasive in linear bacterial genomes | Science www.science.org/doi/10.1126/... @joepeterslab.bsky.social

In 6 days 🧬⚗️🐛⚛️

This week's @science.org has a mollusk paper 🦑🐌 A genome-based phylogeny for Mollusca is concordant with fossils and morphology | Science www.science.org/doi/10.1126/... @sigwartae.bsky.social @squamiferum.bsky.social @kmkocot.bsky.social @sgn.one @oceanspecies.bsky.social

🐯 @science.org @guilhemfaure.bsky.social #Makoto_Saito @maxewilkinson.bsky.social @nquinoneso.bsky.social et al. www.zlab.bio @broadinstitute.org @harvard.edu @hhmi.org #NCBI #NLM #NIH #CRISPR 🐅 #TIGR #RNA #GeneEditing www.science.org/doi/10.1126/...

📣March 7🧬🧪🔬🧫🔭🐛🌊⚛️⚗️💊💉

@science.org RNA polymerase II at histone genes predicts outcome in human cancer 🧬💊 @fredhutch.bsky.social @hhmi.bsky.social www.science.org/doi/10.1126/...

📣March 7🧬🧪🔬🧫🔭🐛🌊⚛️⚗️💊💉

🐛🦋This moth appears to turn into a leaf | Science | AAAS www.science.org/content/arti...

Hi Bluesky! Glad to be here.

🧬🧪Protein codes promote selective subcellular compartmentalization | Science www.science.org/doi/10.1126/... Henry Kilgore @itamarchinn.bsky.social @pgmikhael.bsky.social Ilan Mitnikov, et al. @aihealthmit.bsky.social @whiteheadinstitute.bsky.social @mitofficial.bsky.social

🧬🧪🦠🧫 @science.org www.science.org/doi/10.1126/... @rkoszul.bsky.social @leameneu.bsky.social @christophechapard.bsky.social @chromozz.bsky.social @pasteur.fr @sorbonne-universite.fr @institutcurie.bsky.social + PS www.science.org/doi/epdf/10.... @gfudenberg.bsky.social @vram142.bsky.social

It’s been a tough few weeks. My 10yo daughter was diagnosed with a very rare, aggressive cancer called interdigitating dendritic cell sarcoma (IDCS). I’m reaching out to identify clinicians/patients who have encountered pediatric IDCS or other (non-LCH) dendritic or histiocytic sarcomas cases.

"If anything is forbidden now, it is that medical and science journals, whose duty is to stand for integrity and equity, should bow to political or ideological censorship."

im a very nervous flyer so got on my flight home in a ball of anxiety bc of the crashes / nerves shot through this hell week, but got a great reward right before we landed. world is still very big, world is still very beautiful

@science.org TIR signaling activates caspase-like immunity in bacteria www.science.org/doi/10.1126/... @francoisrousset.bsky.social www.rousset-lab.com @ostermanilya.bsky.social @soreklab.bsky.social et al. www.weizmann.ac.il/molgen/sorek/ 🧫🦠 #microsky #microbiology #bacteria #virus #phage #immune

@science.org Genome recombination on demand | Science www.science.org/doi/10.1126/... a Perspective by @seczmarta.bsky.social Lars Steinmetz @stanford.edu on two studies bit.ly/4hzFRMg + bit.ly/4jyT4Hf that generate large genome rearrangements in mammalian cells @ unprecedented scale #synbio #genome

🧬@science.org Randomizing the human genome by engineering recombination between repeat elements bit.ly/4jyT4Hf @jonaskoeppel.bsky.social @f-raphael.bsky.social @geochurch.bsky.social @proftomellis.bsky.social @leopoldparts.bsky.social +al. @sangerinstitute.bsky.social @harvardmed.bsky.social #synbio

🧬@science.org Multiplex generation and single-cell analysis of structural variants in mammalian genomes bit.ly/4hzFRMg @sudpinglay.bsky.social www.pinglay-lab.com @jshendure.bsky.social et al. @brotmanbaty.bsky.social @hhmi.bsky.social #synbio #genome

Happy Lunar New Year 2025 @science.org

“There has been confusion on the scope of the pause,” said a memo from acting #NIH director Matthew Memoli viewed by STAT. The truth about what's allowed: Ongoing clinical trials can continue, and projects that started before January 20 can continue with procurement More: 🧪🧬🧫💉💊🔬

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🕸️beautiful🕷️