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dmonchaud.bsky.social

🥖😬👨‍🎨 (France) - 🍯🍷🌧️ (Dijon) - 🧬🔬🧪 (CNRS) GATTACA Lab. Chemical biology & genetics. Trying to understand why and how DNA and RNA fold into ωєιя∂ℓу ѕнαρє∂ structures.. https://sites.google.com/site/monchaudchembiolab/

62 posts 1,720 followers 2,422 following

Posts 15 Comments 35

Versatile Click Chemistry-based Approaches to Illuminate DNA and RNA G-Quadruplexes in Human Cells Work by Angélique Pipier and @dmonchaud.bsky.social at ICMUB - Institut de Chimie Moléculaire de l'Université Bourgogne Europe. #LifeSciences #Reproducibility #MolecularBiology

submitted 13 days ago • 0 comments

Remous au CNRS autour du projet de création de labos d’excellence

submitted 35 days ago • 2 comments

Job alert! 3-year PDRA position to work on synthesis of ruthenium complexes as probes for i-motif DNA - please share with anyone looking for positions! Happy to answer any questions 😃 www.jobs.ac.uk/job/DLN413/s...

submitted 31 days ago • 0 comments

A fully detailed protocol to visualize G-quadruplex #G4 DNA/RNA in human cells using clickable G4 ligands (in situ click imaging) now in @bio-protocol.bsky.social Interested?? All you need is: - the clickable ligand: www.sigmaaldrich.com/FR/en/produc... - and the protocol: doi.org/10.21769/Bio...

submitted 33 days ago • 1 comment

La motion de défiance après l'annonce par la bureaucratie du CNRS du définancement de trois quarts des laboratoires, préambule au démantèlement du CNRS, monte gentiment, à 500 signatures/jour. framaforms.org/motion-de-de...

submitted 38 days ago • 3 comments

If you are interested in nucleic acid structures- G4 and beyond. Here is the flyer for the next webinar series, talks range from physics to chemistry up to biology and Medicine

submitted 39 days ago • 1 comment

Quite happy to see this out in @chemistryeurope.bsky.social (with ENS Paris FR, Szeged University HU, UTC Prague CZ) We report here on molecular tools used to detect G-quadruplex #G4 DNA/RNA in vitro, and on the mechanism underlying their unique photophysical properties. 👉 doi.org/10.1002/cmdc...

submitted 40 days ago • 0 comments

The place to be!

submitted 68 days ago • 1 comment

A fully detailed method (40+ steps) to isolate/identify RNA G-quadruplex #G4 in human cells using G4-RNA precipitation (G4RP) protocol G4RP.v1 in @natureportfolio.bsky.social: doi.org/10.1038/s414... & nature.com/articles/s41... & G4RP.v2 now in @cellpressnews.bsky.social: doi.org/10.1016/j.xp...

submitted 75 days ago • 3 comments

Really excited to see this work out! In collaboration with Prof. Jen Prescher, we showed that their cyclopropenone labeling strategy can be applied to structured RNA! Thrilled to work with this fantastic team of scientists. pubs.acs.org/doi/10.1021/...

submitted 77 days ago • 1 comment

One of the ones I am most proud of. In this article, we abided by the very definition of chemical biology #ChemBio to decipher the role that DNA/RNA G-quadruplex #G4 plays, and the effects that the G4 ligands have, in human cells. 👉https://dx.doi.org/10.1016/j.jbc.2024.108040 @cnrs.bsky.social

submitted 83 days ago • 1 comment

📢 New @natrevmcb.bsky.social Review! Jan Karlseder et al. discuss telemore (dys)function in ageing & disease, and efforts to generate a humanised mouse model for telomere research. go.nature.com/3ZxZuhS #NatRevMCB

submitted 84 days ago • 0 comments

My (little) contribution to make the field of G-quadruplex #G4 ligands accessible to all.. .. and to show how pivotal ligands have been as #ChemBio tools to decipher G4 biology. A personal view on the contribution of Pr. Stephen Neidle in a Sp. Issue honoring S. Neidle 😉 👉 doi.org/10.1007/s000...