dwendscheck.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

#IchBinHanna = das aufgeschobene Leben. Ich sag mir seit Jahren: Das mach ich, wenn ich endlich an 1 Ort ankomme. (Most probably dann nicht mehr mit Job in der Wissenschaft, wir wissen ja, die Chancen stehen schlecht.) Bin jetzt 39. Leben unter Vorbehalt seit über 1 Jahrzehnt gar nicht mal so geil.

submitted 23 hours ago • 14 comments

A structural biology compatible file format for atomic force microscopy www.nature.com/articles/s41...

submitted 1 day ago • 0 comments

Isobaric Labeling Update in MaxQuant pubs.acs.org/doi/10.... --- #proteomics #prot-paper

submitted 1 day ago • 0 comments

just your daily reminder that GO annotations are plagued with crap. I was going through some of the proteins annotated as 'Nuclear membrane' and you get GAPDH, ENO1, MX1... Don't trust these annotations. Curate them yourself, as painful as it is, it is worth it for data quality

submitted 3 days ago • 1 comment

Human PBMCs, a highly variable mixed cell population, showing every protein with less than 20% CV. They even state a median CV of 2% in human PBMCs. The result makes no biological or technical sense. So this merits another plug to my CV paper on JPR

submitted 7 days ago • 2 comments

Navigating the Postdoc Experience #JASMS pubs.acs.org/doi/10.1021/...

submitted 6 days ago • 0 comments

Very proud to be part of that team - this was a really long term project with lots of amazing people!

submitted 7 days ago • 0 comments

Every time a student asks a professor whether to do a post doc

submitted 7 days ago • 0 comments

Open #positions‼️ I am looking for: 📌2 Postdocs 📌 1 Research Assistant to join our new research group at the University of Milan. We’ll study #RSV viral replication factories and pioneer new protein degradation technologies #TPD as #antiviral strategies. If interested, drop me a message here 📩 🦠 RT

submitted 8 days ago • 0 comments

Do you like the beaches hot and your electron microscopy cold? 👇

submitted 8 days ago • 0 comments

Simba died, Mufasa has been Reborn (Akta made from the guts of 3 lions) 🦁 we are now down to 2 of these trusty old gray ones.

submitted 9 days ago • 2 comments

News in Proteomics Research blog post | Single cell lipidomics by nanoLC TIMSTOF! proteomicsnews.blogs... --- #proteomics #prot-other

submitted 11 days ago • 0 comments

The answer is yes! Come hear about STARLING this afternoon at the Biophysical Society IDP subgroup symposium! Thread to follow later today... www.biorxiv.org/content/10.1...

submitted 11 days ago • 0 comments

I'll post more about this later. But for a long time, we've observed odd behavior of AlphaFold's ipTM in the presence of disorder and accessory domains. Looking into the math points a way to solving the problem. There are other solutions besides ours. But I think understanding the math is key.

submitted 12 days ago • 0 comments

I have two open postdoctoral researcher positions in my group. I am looking for applicants with interest and expertise in computational structural biology and research software development. These positions are part of GANANA, a collaborative European/Indian project Check www.uu.nl/en/organisat...

submitted 12 days ago • 1 comment

Happy @warscheidlab.bsky.social Team after three days training on the Thermo #Astral. Many thanks to Michal Nadler Holly for such a great course! #TeamMassSpec #proteomics #PhDlife @lakshitaaa.bsky.social @johannes-uni-wue.bsky.social @hirakdas.bsky.social

submitted 13 days ago • 0 comments

Popularity of current DIA data analysis tools (vendor-independent, based on citations of initial publication) Updated for 2024:

submitted 13 days ago • 1 comment

What explains the divergence between RNA and protein levels ? Protein degradation is a HUGE factor. It accounts for up to 50 % of protein variation across proteins & tissue types. www.biorxiv.org/content/10.1... 🧵

submitted 14 days ago • 2 comments

I'm looking for a postdoc with expertise in mass spectrometry to work with me on some exciting projects. Please share! external-careers.jobs.unsw.edu.au/cw/en/job/53...

submitted 14 days ago • 0 comments

Idk what @kathrynslilley.bsky.social did to be labelled as 'spam' by the moderators 😂 but don't let that discourage you from following her. Proteomics and mass spec people give Kathryn a warm welcome

submitted 16 days ago • 3 comments

Happy International Women & Girls in Science Day! Great to see so many women starting out in mass spectrometry careers within the group #FeMS

submitted 15 days ago • 0 comments

Open positions for postdocs and engineers in biochemistry & neuroscience funded by ERC & DFG (www.leibniz-fmp.de/haucke; Rizalar et al (2023) Science; Lo et al (2022) Nat Struct Mol Biol). Apply before 1 April to [email protected] or short.sg/j/52345086; short.sg/j/53217124; short.sg/a/53216739

submitted 27 days ago • 0 comments

wuhuu and it's out! Check out our latest Preprint on Bacteria using archaella for swimming! So much fun figuring it out and great collab with @mariejoest.bsky.social @loumollat.bsky.social Najwa Taib and @sgribaldo.bsky.social

submitted 24 days ago • 0 comments

Calling all #TeamMassSpec experts. I’m planning to revisit the classic SCX fractionation protocol but ran into a challenge - I can’t find a vendor for syringes with metal springs to make stage tips. I’d be so grateful for any suggestions or advice you might have 🙏 *attaching picture as an example

submitted 34 days ago • 4 comments

Now online - the Review "Structured protein domains enter the spotlight: modulators of #biomolecularcondensate form and function" from Nathaniel Hess and @jerelleaj.bsky.social. #PhaseSeparation #ProteinProteinInteraction #Oligomerization #ProteinRNAInteraction authors.elsevier.com/sd/article/S...

submitted 35 days ago • 0 comments

Check out Artem's precomputed interactive AF2BIND (small molecule binding site) predictions for the human proteome. 🤩 gpubio.xyz/humanproteome

submitted 35 days ago • 0 comments

Congrats to Yuchen He and Felix Kraus! This paper showcases fast multi-omics sample prep and our multi-omic single shot technology: Global cellular proteo-lipidomic profiling of diverse lysosomal storage disease mutants using nMOST | Science Advances #multiomics www.science.org/doi/10.1126/...

submitted 35 days ago • 0 comments

Excited to share our new preprint! Exceptional work by @mikelangelipid.bsky.social identifies the first #LipidDroplet lipid quality control pathway! LD-localized FSP1 safeguards neutral lipids from peroxidation and prevents #ferroptosis. 🤩https://www.biorxiv.org/content/10.1101/2025.01.06.631537v1

submitted 50 days ago • 1 comment

Anybody still looking for their friends on this site? 🧪 If membranes or the molecules therein are your thing, please check out these TWO starter packs on membrane proteins, lipids and transport processes! With many new arrivals since the last post! go.bsky.app/AEeXh86 go.bsky.app/PnXecJZ

submitted 43 days ago • 4 comments

Don't publish (or allow) papers with a web server and NO source code. Servers die after 3+ years, taking the software with them. Number of tools are lost to closed-source. #opensourceforscience

submitted 37 days ago • 1 comment

Preprint of our first research article is live! Are you curious about: How surface induced unfolding can benefit your research? Reproducibility of gas phase unfolding measurements? Rowan Matney has worked hard to answer these questions, and more! #TeamMassSpec #Preprint doi.org/10.26434/che...

submitted 37 days ago • 1 comment

#Teammassspec with an Astral, do you use file size as a QC metric and if so, how? For qTOFs I can see trends in performance. But with a trapping mechanism, I suspect AGC/maxIT leads to less ion intensity variability across samples (a good feature) however it makes file size less useful as a metric.

submitted 37 days ago • 1 comment

Can someone running XCalibur 4.5 with a Waters M-class and 96 well plates please get in contact with me? We are trying to switch to 96 well plates from 48 vial racks and are having problems. I need some guidance! #massspechelp

submitted 37 days ago • 1 comment

Less than one month until I retire from full time work. I am going to offer training and consultancy from early march 2025, so if you know of anyone who would like training on LCMS systems or consultancy on proteomics sample prep etc please mention my name.

submitted 43 days ago • 1 comment

Today in cursed products.

submitted 40 days ago • 2 comments

Bitte zielgruppengerecht teilen: Heute, 18.01., ab 14:05 im #DLF: Thema #eXit – Sollten wir dem ehemaligen #Twitter, das Elon #Musk nach seinen Zielen zu X gemacht hat, den Rücken kehren? Was gewinnt oder verliert die Wissenschaft, wenn sie zu #Bluesky, #Mastodon oder LinkedIn wechselt? 🎙️ #WissXit

submitted 40 days ago • 0 comments

Coming from struct. biology, I tend to focus on folded protein domains & interactions where at least one partner is such a domain. (The other might be another folded domain, a short protein motif, or another molecule like RNA). Do such interactions explain condensate formation? Often, they seem to.

submitted 41 days ago • 1 comment

Apparently many alleles encoding resistance to some antibiotics were around before clinical use of those antibiotics became widespread, they just weren't very common!

submitted 40 days ago • 0 comments

Using the peace and silence of an early Saturday morning to run a few sample 🫠 #Phdlife #labrat #peroxisomes #proteomics #IchBinHanna and #TeamMassSpec

submitted 40 days ago • 3 comments

It's about time we have a conversation about the role of structured protein domains in form and function of bimolecular condensates. Proud of graduate student Nate Hess for taking the lead on synthesizing these ideas and identifying important gaps in the field!! www.sciencedirect.com/science/arti...

submitted 40 days ago • 3 comments