elimereu.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

Today, 2 postdoctoral researchers from #CarrerasLeaders have led our Young Researcher Seminars🙌 🧑‍🔬👩‍🔬 Gerard Martínez (@scuartero.bsky.social lab) has presented his work on myeloid leukemia of Down syndrome and Alessia Buratin ( @elimereu.bsky.social lab) on machine learning to enhance CAR-T therapies

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ResolVI - addressing noise and bias in spatial transcriptomics www.biorxiv.org/content/10....

submitted 30 days ago • 0 comments

🚨 New paper alert 🚨 Our Human Microglia Atlas (HuMicA) characterizes #microglia subpopulations across 6 distinct #neurologic diseases. www.nature.com/articles/s41...

submitted 41 days ago • 1 comment

Great work on characterizing human microglia in 6 😱 neurological disorders! In collaboration with my next door colleagues at @eballestar.bsky.social’s lab!!

submitted 41 days ago • 0 comments

Made a #short about my internal conflicts on academic publishing #AcademicSky #PhDlife "Stop asking me where I want to publish our paper. I don't care...I just want people to read it. And maybe learn from it. Even build on it. Ok?" Is this #hopecore or #hopelesscore youtube.com/shorts/GV7NJ...

submitted 49 days ago • 0 comments

Researchers from the Crick have found that over 40% of variation in the way kidney cancer behaves is due to non-genetic factors. The findings were led by Angel Fernandez Sanroman with senior author Samra Turajlic www.crick.ac.uk/news-and-rep...

submitted 49 days ago • 0 comments

Excited to share our new study of #genomics🧬, #EHR📈 + treatment outcomes of 78K patients across 20 #cancers! We identified >700 mutations predicting which drugs💊 are effective for individual patients. Our #ML model predicts who responds well to immunotherapies. #precisioncancer

submitted 49 days ago • 1 comment

scRepertoire 2: Enhanced and Efficient Toolkit for Single-Cell Immune Profiling www.biorxiv.org/content/10.1...

submitted 57 days ago • 2 comments

Join us to decode the immune system with AI and advance immunotherapy research. 🌍 Part of RAMON LLULL - AIRA: 33 prestigious international postdoc fellowships. 📅 Apply by Feb 20. Start June 2025. 🔗 ramonllull-aira.eu 📩 [email protected] #AI #Postdoc #Genomics #Immunotherapy #Research

submitted 67 days ago • 0 comments

"Polls have shown that principal investigator biologists now spend up to 40 percent of their time—it’s a shocking number, 40 percent of their time—writing grants." www.harvardmagazine.com/2025/01/harv...

submitted 73 days ago • 15 comments

1/🚀 Excited to share RegVelo, our new cell model combining RNA velocity with gene regulatory network (GRN) dynamics to model cellular changes and predict in silico perturbations. Here's how it works and why it matters! 🧵👇 biorxiv.org/content/10.1101/2024.12.11.627935v1

submitted 76 days ago • 3 comments

Last minute call !! Join us soon for the first Single-cell and spatial metabolomics online day! We have more than 700 registrations! Zoom, doors open 14.30 CET = 8.30 Boston, registration (mandatory) below. It's time for the program reveal! 1/4

submitted 79 days ago • 2 comments

Modeling and predicting single-cell multi-gene perturbation responses with scLAMBDA www.biorxiv.org/content/10.1...

submitted 78 days ago • 0 comments

Have you been thinking hard about statistical modelling of scATAC-seq data? (No.) Luckily for you, @aaronkwc.bsky.social has! Aaron will help you grok: What's going on? What is TF-IDF? Is there really single-cell level chromatin information? Check it out 👇 www.biorxiv.org/content/10.1... 🧪🧬💻

submitted 79 days ago • 2 comments

Quantifiable TCR repertoire changes in prediagnostic blood specimens among patients with high-grade ovarian cancer www.cell.com/cell-report...

submitted 79 days ago • 0 comments

Allogeneic CD19-targeted CAR-T therapy in patients with severe myositis and systemic sclerosis www.sciencedirect.com/science/arti... With commentary: Off-the-shelf CAR-T cells could prove paradigm shifting for autoimmune diseases www.sciencedirect.com/science/arti... in @cellpress.bsky.social

submitted 79 days ago • 0 comments

Single-cell spatial multi-omics and deep learning dissect enhancer-driven gene regulatory networks in liver zonation www.nature.com/articles/s41... in @naturecellbiology.bsky.social by @steinaerts.bsky.social

submitted 83 days ago • 0 comments

tcrBLOSUM: an amino acid substitution matrix for sensitive alignment of distant epitope-specific TCRs academic.oup.com/bib/article...

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Researchers at the Crick and @uclofficial.bsky.social have developed an algorithm that can identify which cell populations within a tumour are growing the fastest. The findings are part of the @cancerresearchuk.org-funded TRACERx study www.crick.ac.uk/news-and-rep...

submitted 90 days ago • 1 comment

Only a subset of patients respond to immunotherapy Why? Which ones? We conducted an unbiased analysis of response biomarkers and found that hundreds of possible biomarkers collapse into five latent, orthogonal factors that underlie immunotherapy response. www.nature.com/articles/s41...

submitted 92 days ago • 4 comments

Hi! I just compiled some of the new Barcelona cancer labs! Many more missing, so let me know if anyone needs to be added! go.bsky.app/AkCGugm

submitted 92 days ago • 5 comments

A new approach helps examine the proportion of cancerous and healthy stem cells in patients with chronic myeloid leukaemia and how this influences treatment outcomes. https://buff.ly/3ULmWp6

submitted 99 days ago • 0 comments

Would you prefer to lead a lab alone or together with a science buddy? How interesting would be a research institute where joint labs are the standard?!

submitted 96 days ago • 26 comments

1/ 🧬 Single-cell genomics reveals biological variations beyond cell types. Unveiling these in separate latent dim’s is known as disentanglement. Led by @AmirAliMoinfar, we develop DRVI to learn nonlinear, disentangled & interpretable latent spaces. biorxiv.org/content/10.1101/2024.11.06.622266v1

submitted 98 days ago • 3 comments

More than 40 @natureportfolio.bsky.social papers on the Human Cell Atlas.. Biology is changing so fast.. www.humancellatlas.org

submitted 98 days ago • 2 comments

Out today in Nature: "The Human Cell Atlas"! In my News and Views, I compare the cell atlas to early naturalists creating an atlas of South America. Researchers mining this cell atlas can now make big discoveries, just as the next naturalists then discovered evolution. www.nature.com/articles/d41...

submitted 98 days ago • 3 comments

Hello world!! 🌍I’m happy to join this community with new and old scientists friends! Stay tuned if you want to know more about our science in #singlecell applications to biomedical research! Soon a new benchmarking of sc multiomics integrations in reference data!

submitted 98 days ago • 0 comments

Vacancy: @bsc-cns.bsky.social is looking for #AI Institute Director We are establishing a new Institute of #ArtificialIntelligence The selected candidate will lead the Institute's operations & strategic vision, driving research at the intersection of #HPC & #AI ➡bsc.es/Z9Z #trabajo #feina #job

submitted 98 days ago • 0 comments