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erainerolab.bsky.social
We are in @mcb-sheffield.bsky.social, in the School of Biosciences at the University of Sheffield. We are interested in understanding how the extracellular matrix controls cancer cell migration, growth and metabolism. @plosbiology.org Editorial Board Membe
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SAVE THE DATE: 12th ISCaM meeting - Brussels, 2-4 July 2025. Travel awards available, abstract submission deadline: 30th of April. #spatialMetabolomics #TumourMicroenvironment #CircadiaClock #tumourAcidosis #immunometabolism #cancer #therapyResistance Info & registration here: iscam2025.org

Today we welcome Dr Catherine Hogan @cardiffuniversity.bsky.social, who will present her work on 'Cell-cell interactions with normal epithelial neighbours determines KRAS mutant cell behaviour and fate'. 1pm - Alfred Denny Conference room

Thrilled to know that our own Zhe has been selected to present his work at the #Biologist@100 conference @bscb-official.bsky.social! @mcb-sheffield.bsky.social

POSTDOC POSITION: Really exciting project between Owen Sansom and my lab investigating mechanisms of colorectal cancer metastasis using organoid transplants + in vivo CRISPR. @cruk-si.bsky.social www.jobs.gla.ac.uk/job/research...

Our new #Mechanobiology collection examines the mechanical properties & interactions that shape the fundamental operations & structures of cells. Delve into diverse mechanical properties of membranes, organelles & other structures within & among cells 👉 https://buff.ly/3EK0uaq

And learn more about the role and how to apply here: www.cruk.manchester.ac.uk/career/mi-25... Please share with anyone who might be interested!

#ECMatrix researchers, please share: Just under 2 weeks until the abstract deadline (21st Feb) for the 3-day Matrix Nexus meeting in Freiburg. Topics include #cancer #collagens #proteoglycans #proteases #tissueengineering & a session dedicated to #ECRs! www.matrixbiologie.de/annual-meeti...

#FREE #Bioinformatics for #Biologists course: An Introduction to Linux, Bash Scripting, and R 10 February 2025–8 February 2026 coursesandconferences.wellcomeconnectingscience.org/event/bioinf...

SAMCell: Generalized Label-Free Biological Cell Segmentation with Segment Anything www.biorxiv.org/content/10....

Hot from the press for #CellMigration + #Nucleus aficionados Karling @helenweavers.bsky.social lab show *in vivo* how immune cell adapt quickly to confined microenvironments during motility. Live-cell imaging, image analysis, #Drosophila ! Full @emboreports.org www.embopress.org/doi/full/10....

"Imagine a DAPI-like stain, but for the extracellular matrix." That's basically how this work was pitched to me by Kayvon and Antonio a year or so ago. Now the final product really delivers. Read about their versatile label for ECM in living tissues here: www.nature.com/articles/s41...

Stroma gene signature predicts responsiveness to chemotherapy in pancreatic ductal adenocarcinoma patient-derived xenograft models 🧪 #PancreaticCancer febs.onlinelibrary.wiley.com/doi/10.1002/...

Exciting news! #MembraneTrafficking online seminars with @felixmendu.bsky.social @franbottanelli.bsky.social and me are back! Check the spectacular Jan-April 2025 lineup. Details (Zoom links, calendar invites) on the mailing list, Slack group & website: felixcampelo.wixsite.com/membranetraf...

Love this #ResearchCulture thread - and now looking forward to reading the paper - sounds like a good one to discuss in the @officialuom.bsky.social Research Culture Working Group

Time to share our organelle proteome paper out in @cellcellpress.bsky.social: doi.org/nzwz We created a spatial map of human cells using organelle immunoprecipitation at scale. Locate your fav protein among the 7,600 we mapped across 19 subcellular compartments: organelles.sf.czbiohub.org/ 1/3 🧪

Proud to display our LEAF silver certificate!! @helenkmatthews.bsky.social @mcb-sheffield.bsky.social

Congratulations Dr Sherry 🥂 We’ll miss you

📣 I’m looking for PhD students to work at the intersection of theoretical physics & biology -topics range from active cell mechanics to collective cell migration & tissue patterning! Feel free to reach out for more info (DM/email)! Please repost / share 🙂

We made a photoswitchable HaloTag (psHaloTag), which can reversibly turn-on fluorogenic dyes upon illumination 💡. Congrats to Franzi, Bego and all co-authors, check out our preprint below 👇 www.biorxiv.org/content/10.1...

I’m delighted to share that I’ve been promoted to Senior Lecturer!!!! Thank you very much to all the members of my lab, past & present: Mona Nazemi, Montserrat Llanses Martinez, Keqian Nan, Bian Yanes, Shengnan Yuan, Shahd Alhadid, Haya Alomaim, Rachele Bacchetti, Zhe Bao, Ifeoluwa Oyelade (1/2)

We're thrilled to see that our paper has been selected among the editors’ top picks for 2024!!! journals.plos.org/plosbiology/...

Glucose limitation protects cancer cells from apoptosis induced by pyrimidine restriction and replication inhibition pubmed.ncbi.nlm.nih.gov/39592843/

I read this on my lunch break. 😉 Great article Christian.

Our recent paper is now highlighted in #Kudos: link.growkudos.com/1pwlc1v9n28

Unlocking the secrets of metastasis: Cancer cells' 'eating' ability could lead to new treatments medicalxpress.com/news/2024-12... via #medical_xpress

Opening #actin2024 is Sheffield's own Zhe Bao from @erainerolab.bsky.social @mcb-sheffield.bsky.social

In groundbreaking research led by @erainerolab.bsky.social @sheffielduni.bsky.social @mcb-sheffield.bsky.social, supported by @cancerresearchuk.org and the @acmedsci.bsky.social, scientists have made an important discovery about how cancer cells migrate sheffield.ac.uk/biosciences/...

🎉 The latest paper from out lab by #Montse_Llanses with Keqian Nan, Zhe Bao, Rachele Bacchetti Shengnan Yuan & Joe Tyler is out!!! @plosbiology.org @mcb-sheffield.bsky.social journals.plos.org/plosbiology/...

Oncogenic RAS Induces a Distinctive Form of Non-Canonical Autophagy Mediated by the P38-ULK1-PI4KB Axis https://www.biorxiv.org/content/10.1101/2024.12.10.627736v1

Mitochondrial mechanotransduction through MIEF1 coordinates the nuclear response to forces pubmed.ncbi.nlm.nih.gov/39433949/

Proteolysis-free amoeboid migration of melanoma cells through crowded environments via bleb-driven worrying pubmed.ncbi.nlm.nih.gov/38870943/

Romani, P., Valcarcel-Jimenez, L., Frezza, C., & Dupont, S. (2021). Crosstalk between mechanotransduction and metabolism. Nature Reviews Molecular Cell Biology, #EpithelialMechanicsReview https://doi.org/10.1038/s41580-020-00306-w

Press release on the nice paper from @mark-morgan.bsky.social lab on the integrin αVβ6-HER2 cross-talk. www.science.org/doi/10.1126/...

Fantastic lab Christmas party yesterday, with @helenkmatthews.bsky.social lab! Thanks to Rachel and Zhe for organising! @mcb-sheffield.bsky.social

Excited to join the Editorial Board of #PLOSBiology, the #PLOS flagship journal in the Life Sciences, that's blazing a trail in support of selective, equitable #OpenScience and reaching global audiences to help advance science faster.

Only 10 days left to apply for our MRC-funded PhD project with @erainerolab.bsky.social and Zoe Mann -if you are interested in working at the interface of developmental/stem cell and cancer biology do not miss this out-happy to provide more info-for details check: www.findaphd.com/phds/project...

Metabolism and mRNA translation: a nexus of cancer plasticity www.cell.com/trends/cell-...

Big news about this paper soon!

Pre-announcing the 10th Biennial European CellMech conference organized in Leuven 🇧🇪 from September 30th to October 3rd, 2025. cellmech2025.org Save the date !

Here is the most recent preprint from our most recent PhD graduate, Dr Nicolas Pasquier. Orientation of mucinous CRC apicobasal polarity is regulated by tumor-stroma interactions. This work was a collaboration with the Jaulin lab at the Gustave Roussy Institute. www.biorxiv.org/content/10.1...