erikvandis.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

#TheMoreTheMerrier! Wu, Yan &co show @cp-immunity.bsky.social that antiviral OAS alerts neighboring cells by producing 2-5A which via gap junctions or exporter/importer activates RNaseL, protecting against infection or tumor growth! #ScienceSavesLives dlvr.it/TJB0nT

submitted 1 day ago • 0 comments

I started out our lab meeting today with a ~15 min summary of what the NIH does, indirects, current attacks on the NIH, and what we can do to fight. Some of my lab members follow the news, some don't, but I think they were all highly interested in learning. Happy to send these slides to anyone

submitted 5 days ago • 7 comments

In light of policies to defund biomedical research, and with judicial hearings happening today, we hope to highlight the many ways biomedical research improves people's lives, and to convey how damaging the proposed cuts would be... not just for us researchers, but for everyone.

submitted 5 days ago • 2 comments

#NoTimeToDie! Lien, @fitzgeraldkate.bsky.social &co show @pnas.org that Raver1 controls the splicing of RIPK1, impacting caspase-8 activation, gasdermin D & E cleavage, IL1 & IL18 production & pyroptic cell death in the context of Yersinia infection in vivo! #ScienceSavesLives

submitted 5 days ago • 0 comments

Opinion piece from UW scientists Jakob von Moltke @jmoltke.bsky.social , Patrick Mitchell, and Thornton Thompson advocating against proposed cuts to biomedical research. Washington (state) readers especially take note: www.heraldnet.com/opinion/comm...

submitted 5 days ago • 0 comments

🧪 New research suggests raccoon dogs may have been the source of COVID-19, potentially transmitting it to humans at Wuhan's Huanan Seafood Market. Genomic data links their DNA to virus-positive samples. 🩺 🛟

submitted 5 days ago • 2 comments

DOGE By The Numbers theonion.com/doge-by...

submitted 6 days ago • 189 comments

Bluesky post I’m very excited to share a preprint of the bulk of my thesis work in @sunnyshinlab.bsky.social where we investigate how dendritic cells respond to Legionella pneumophila www.biorxiv.org/content/10.1...

submitted 5 days ago • 1 comment

Patrick Mitchell (@psmitchej.bsky.social), Thornton Thompson and I wrote an OpEd, with support from 650+ biomedical researchers across Washington State (450+ at time of submission). www.heraldnet.com/opinion/comm... List: www.moltkelab.com/s/NIH-OpEd-S...

submitted 5 days ago • 0 comments

THIS IS HUGE! Researchers at Memorial Sloan Kettering Cancer Center say results of a Phase I trial of an mRNA vaccine aimed at preventing pancreatic cancer show promise. The vaccine PREVENTED the cancer from coming back in patients who had already received treatment for MORE THAN three years. 🧪🧵⬇️

submitted 5 days ago • 350 comments

🚨 We're Hiring! 🚨 Join Van Andel Institute as a Research Technician! 🧬🐟🔬 Work in Metabolism, Neuroimmunology, & Developmental Biology with #zebrafish models & imaging—training provided! 📍 Grand Rapids, MI 📅 Full-time, hands-on lab work 📝 Apply: tinyurl.com/3vkzt7yt DM for details & please RT 💙🙏

submitted 5 days ago • 0 comments

We're still getting this drip-drip of stories implying mounting evidence for a lab leak (despite no actual evidence). Meanwhile, the increasingly strong case for zoonosis rarely makes headlines.

submitted 8 days ago • 27 comments

@katherinejwu.com getting straight to the ❤️ of the crisis. This current attack on science must be stopped to protect all Americans.

submitted 11 days ago • 0 comments

Raver1 links Ripk1 RNA splicing to caspase-8-mediated pyroptotic cell death, inflammation, and pathogen resistance www.pnas.org/doi/10.1073/...

submitted 12 days ago • 0 comments

Exciting new work out of the Daugherty lab - congrats Dustin!

submitted 14 days ago • 0 comments

Mechanisms of NLRP3 activation and inhibition elucidated by functional analysis of disease-associated variants www.nature.com/articles/s41... @natimmunol.bsky.social @sethlucianmasters.bsky.social

submitted 16 days ago • 1 comment

The US plans to cut billions in reimbursements to medical researchers for items such as hazardous waste disposal.

submitted 18 days ago • 170 comments

@jeremymberg.bsky.social Have you or anyone else heard about any Admin supplements to Promote Research Continuity (“Maternity Leave Supplements”) being discontinued? A new Asst. Prof. at home with a tiny baby just had hers disappear from her ERA commons account while waiting for her NOA. Awful.

submitted 17 days ago • 4 comments

Hexokinase detachment from mitochondria drives the Warburg effect to support compartmentalized ATP production https://www.biorxiv.org/content/10.1101/2025.02.07.637120v1

submitted 18 days ago • 1 comment

Check it out! Another novel RNA modification - ADP-ribosylation - that was previously only known on proteins. A cousin to #glycoRNA 👏 www.nature.com/articles/s41...

submitted 20 days ago • 3 comments

MDSC depletion during immunization with heat-killed Mycobacterium tuberculosis increases protection against BCG infection. https://www.biorxiv.org/content/10.1101/2025.01.31.635639v1

submitted 21 days ago • 0 comments

Insights from Cadena & Blumenthal: Bernaleau et al. @rebsamenlab.bsky.social (https://buff.ly/3ZrE70d) show that CCDC134 located in the ER is required for TLR biogenesis by controlling the N-glycosylation, folding, and stabilization of the ER chaperone Gp96. https://buff.ly/4gwjt5N

submitted 21 days ago • 0 comments

Welcome, Dr. Jones, to the University of Washington as our 34rd President.

submitted 23 days ago • 3 comments

Way to go Grant! 🙌🔬👨🏻

submitted 23 days ago • 0 comments

Excellent work Elizabeth et al!

submitted 23 days ago • 0 comments

Shoutout to all of the exceptional Black scientists who have contributed to and are currently contributing to virology research! Your work is vitally important to understanding basic virology controlling viral diseases worldwide! #BlackHistoryMonth

submitted 23 days ago • 2 comments

Well the award for most cowardly, boot-lickingest academic society has squarely gone to the American Society of Microbiology, who has taken down features of various non-white scientists. Absolutely pathetic behavior. Those articles are now coming up as “under review”. Truly sickening cowardice here.

submitted 23 days ago • 353 comments

Shigella OspF blocks rapid p38-dependent priming of the NAIP-NLRC4 inflammasome https://www.biorxiv.org/content/10.1101/2025.02.01.636075v1

submitted 23 days ago • 0 comments

Since 1991, the NIH Science Education Partnership Award (SEPA) is dedicated to K-12 students & funds innovative STEM educational projects. It supports our EvolvingSTEM program that engages >1500 students/yr in authentic research. 🚨Its Program Announcement (PAR-23-137) is now GONE.😡 nihsepa.org

submitted 27 days ago • 10 comments

Journal Editor: "What is the mechanism?" Scientist: "Better than an answer—I have a tremendous amount of data!"

submitted 27 days ago • 2 comments

Nucleotide-derived bacterial alarmones attenuate the induction of type-I interferon responses in a murine macrophage reporter cell line https://www.biorxiv.org/content/10.1101/2025.01.27.635077v1

submitted 29 days ago • 0 comments

Accelerated Adaptation of SARS-CoV-2 Variants in Mice Lacking IFITM3 Preserves Distinct Tropism and Pathogenesis https://www.biorxiv.org/content/10.1101/2025.01.27.635150v1

submitted 29 days ago • 0 comments

To help people understand the importance of NIH, share what you’ve used their funding for (in easily understandable terms). I’ll start: my NIH postdoc funding helped me develop and test AI tools that could identify skin cancer across diverse skin tones.

submitted 30 days ago • 43 comments

What orchestrates the dance of innate immunity? Lauren Spector and I reflect on how the NLRP3 inflammasome dynamically interacts with organelles to coordinate immunity—thanks to the remarkable work of researchers in the field! journals.lww.com/immunometabo...

submitted 29 days ago • 0 comments

The early-career success of academic researchers is better predicted by their publication record during their postdoctoral years than by where they obtained their PhD, according to a study of 45,572 academic careers worldwide. In PNAS: www.pnas.org/doi/10.1073/...

submitted 30 days ago • 1 comment

Excited to share our latest paper out today in @naturecomms.bsky.social ! Great work led by postdoc Ales Drobek showing for the first time the critical role in vivo of the SLC15A4/TASL/IRF5 pathway that we discovered few years ago. #ImmunoSky #InterferoSky

submitted 33 days ago • 1 comment

The type I IFN-IL-27 axis promotes mRNA vaccine-induced CD8+ T cell responses https://www.biorxiv.org/content/10.1101/2025.01.16.633383v1

submitted 36 days ago • 0 comments

The type I IFN-IL-27 axis promotes mRNA vaccine-induced CD8+ T cell responses www.biorxiv.org/content/10.1...

submitted 35 days ago • 0 comments

What is the biologic basis for itch? www.cell.com/current-biol... For more on the PIEZO ion channels erictopol.substack.com/p/ardem-pata... w/ @ardemp.bskyverified.social

submitted 37 days ago • 3 comments

Really enjoyed reading in #MolecularCell "RNA sensing induced by chromosome missegregation augments anti-tumor immunity" They found dsRNA sensing is equally important in the #interferon response to micronuclei induced by inhibition of spindle assembly. www.sciencedirect.com/science/arti...

submitted 37 days ago • 1 comment

Hello Bluesky friends! I am a #newPI starting at UC Irvine in April, interested in gene regulation and functional genomics in stem cell models of development (esp neural crest). We are hiring at all levels – please reach out/spread the word! sskimlab.org

submitted 37 days ago • 4 comments

New preprint documenting a common but oft-under-appreciated source of noise, which is ignored at one's peril: "These findings reveal extensive barcode swapping during AAV pooled packaging that significantly compromises cell type specificity measurements from barcoded enhancer AAVs."

submitted 37 days ago • 1 comment

Mark your calendars Cytokines 2025 Westin Seattle! Abstract submission is opening soon. Make sure to note these important deadlines: -Abstract Submission deadline: Wednesday 18 June -Early-Bird Registration Deadline: Friday 25 July Group room rate $236 seattle.cytokinesociety.org for more details

submitted 39 days ago • 0 comments

🚨 Postdoc Opportunity Alert 🚨 Are you passionate about advancing our understanding of mucosal immunity to respiratory viruses like coronaviruses and influenza? Join our team to conduct cutting-edge research! 🧫🧬 📍 Location: Hamilton, Montana, USA www.training.nih.gov/jobs/pdirta-...! 🧪✨

submitted 40 days ago • 0 comments

My postdoc @rose-hill.bsky.social and colleague @thepenkpanther.bsky.social received mentoring awards @scripps.edu! Rose was nominated by an undergraduate student she mentored for all four years. Very proud!

submitted 40 days ago • 1 comment

My thesis paper is out in @elife.bsky.social! We look forward to making it even better as we respond to our (very kind) reviewer comments. Till then, see how we created a novel microglia replacement system & showed that brain macs can drive brain interferonopathy! elifesciences.org/reviewed-pre...

submitted 51 days ago • 2 comments

If you like Wallace's blue-torial (what are we calling the tweetorial equivalent over here btw) and are going to ASCB, look out for my talk Tues. Dec 17th on how the microtubule cytoskeleton dictates RNA regionalization in Stentor! #cellbio2024 #stentor #protist #NIHMOSAIC

submitted 86 days ago • 1 comment