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erinmhumphries.bsky.social
Cancer #Proteomics Researcher | Mass Spec Enthusiast | Analytical Chemist | FFPE #Phosphoproteomics | She/her | My opinions are my own
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There is still time to apply for the Q2 empowerment award! 🏆

Another chapter of my PhD thesis has been published! We observed a strong overlap and correlation between #FFPE (formalin-fixed paraffin-embedded) and FF (fresh-frozen) tissues in #proteomics and #phosphoproteomics. pubs.acs.org/doi/10.1021/...

Congratulations to my colleagues Jennifer Koh and Erin Sykes on their latest FFPE paper investigating the stability of tissue sections stored at room temperature versus -80°C over 48 weeks 🎉

Opportunity for lecturer in medicinal chemistry at University of Adelaide (Australia) eligibility: women & non-binary candidates | ref: 515560 | closing: 11-Feb-2025 #MedChem #ChemJobs #OzChem #chemsky 🧪 careers.adelaide.edu.au/cw/en/job/51...

🚨 More research on single-cell proteomics! We evaluated how formaldehyde-based fixation preserve proteome state, drug response and cell integrity. Ultimately, cell fixation can facilitate access to #singlecell by enabeling sample shiping and prolonged sorting 📦 pubs.acs.org/doi/10.1021/...

Calling all #TeamMassSpec experts. I’m planning to revisit the classic SCX fractionation protocol but ran into a challenge - I can’t find a vendor for syringes with metal springs to make stage tips. I’d be so grateful for any suggestions or advice you might have 🙏 *attaching picture as an example

#Teammassspec with an Astral, do you use file size as a QC metric and if so, how? For qTOFs I can see trends in performance. But with a trapping mechanism, I suspect AGC/maxIT leads to less ion intensity variability across samples (a good feature) however it makes file size less useful as a metric.

Congratulations to Prof. Bernhard Küster on being selected as the 2025 Karger Medal Recipient. Join us for a celebration on Monday, March 10 ! cos.northeastern.edu/barnett/abou...

🚀 Robust and high sensitivity #proteomics: Our Nature protocol demystifies #PASEF workflows and provides ready-to-use dia-PASEF & synchro-PASEF methods. Find out how to achieve 7,000 protein groups or 29,000 phosphosites in 21min. Let's explore! #TeamMassSpec #Bruker doi.org/10.1038/s415... 1/🧵

A reminder that registrations for AusOMICS are now open. For more details visit: www.ausomics.com Renew your ANZSMS membership for 2025-2026 today to take advantage of discounted registration rates for AusOMICs. www.anzsms.org/membership/ #TeamMassSpec #massspectrometry #massspec

1/11 - With Karin Mitosch and Clément Potel + colleagues in Savitski lab and @typaslab.bsky.social @embl.org, I’m very happy to share our discovery of a hyper-promiscuous phage protein kinase (T7K) which broadly deactivates bacterial defenses! 🦠 www.biorxiv.org/content/10.1...

(1/5) 🚨 New Research Alert! 🚨 Excited to share our latest work in @embojournal.bsky.social "Towards routine proteome profiling of FFPE tissue: insights from a 1,220-case pan-cancer study" ✨ doi.org/10.1038/s443... 📌 Key Highlights:

Because Jens and I don't hammer on enough about proteoforms...... doi.org/10.3389/fcel...

Our proof of concept paper has just been published in the Journal of Proteome Research. Demonstrates our capabilities for blood proteomics, using both immunoassay and mass spec for fractionated blood and VAMS (dried blood spot) devices. #massspec #proteomics pubs.acs.org/doi/10.1021/...

Registrations are open for AUS-oMicS, a joint meeting of Australasian Proteomics Society, @ozglyco.bsky.social, Australian & NZ Metabolomics Society and @anzsms.bsky.social . Registrations & abstract submissions are now open! #TeamMassSpec #massspectrometry www.ausomics.com

PhosX is out! doi.org/10.1093/bioi... Leveraging the latest kinase specificity maps by the Cantley, Yaffe, and Turk labs and a rank sum statistic we created PhosX so now we can predict activities for nearly all kinases in your phosphodata, including the understudied ones. Check it out!

Still time to register to awsome Glycobiology Gordon Research Conference 2025. We have a fantastic line of speakers and this will be top #glycotime in Tuscany !! Register at www.grc.org/glycobiology...

Quantifying proteins from archived tissue continues to improve. #proteomics www.biorxiv.org/content/10.1...

The Darlene Solomon Award applications for the 13th #ISLS are now OPEN ❕ 📅 Application deadline: 1st December More information ➡ femalesinms.com/darlene-solo... Application ➡ a airtable.com/appuR3EVJ32W... Co-sponsored by @Agilent

“To better understand how a living cell functions and adapts to changing conditions we need systems level perspective and experimentation for which proteomics is the essential technology.” Prof Ruedi Aebersold. ProCan MultiOmics conference kicking off with King of proteomics 🌟