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escolizzi.bsky.social
Tenured scientist @INRIA, Lyon. Studying how microbes evolve new stuff with computer simulations.
9 posts 571 followers 702 following
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1/46 Hey folks, we have a new paper out on the MuLTEE. Strap in and I’ll tell you the story of how this “little paper on polyploidy” turned into the most data rich paper our lab has produced, largely thanks to the leadership and work ethic of @kaitong25.bsky.social. www.nature.com/articles/s41...

Excited to share our paper published in @currentbiology.bsky.social that explores the consequences of having multiple genomes in a bacterial model system and it’s benefits in a multidrug environment ! www.cell.com/current-biol...

Our minireview on BGC evolution being shaped by genomic & ecological context is now live on mSystems: journals.asm.org/doi/10.1128/... #secmet #MEvoSky

It wasnt easy for #phylosymbiosis to get off the ground, but it is now. Here is the first study to suggest that phytoplankton have phylosymbiotic microbiomes. On a personal note, it’s fulfilling to watch the term, the concepts, and approaches broadly take flight. www.biorxiv.org/content/10.1...

I'm so happy that I can finally share the results of my first postdoc paper with @baym.lol!!! Turns out plasmids are an amazing system to study multi-scale evolution and we can track within-cell and between-cell dynamics! (1/n) www.biorxiv.org/content/earl...

🚨This is happening tomorrow!! DM us or sign up📝 to our mailing list for the zoom link 🎥 Please repost and share among your networks for our first talk this new year

How do organelles fit together inside a crowded cell? Answering this question requires a way to image many organelles in a whole cell at high resolution with high throughput. Our new preprint shows how to do this in yeast using soft x-ray tomography www.biorxiv.org/content/10.1...

A new paper of Saskia Wilmsen and me on "Defining organismality" just came out in Biological Theory . Open access: rdcu.be/d6but 🧵👇

Myself & James Horton have recently had the pleasure of working with @statedclearly.bsky.social as advisors for his latest video on #mutationbias. Please watch, share, and while you're at it have a look at the rest of Jon's videos. #evolution #scicomm #microsky 🧪 www.youtube.com/watch?v=pqgm...

The final version of our latest Starship manuscript is out!🚀We study the evolution of a gene cluster for formaldehyde resistance to show that #HGT mediated by giant Starship #transposons is a recurrent force in #fungal adaptation. www.science.org/doi/full/10....

New Preprint! We identified Pseudomonas in wild liverworts and explored what makes them virulent. www.biorxiv.org/content/10.1...

How best to avoid the costs of bearing a #plasmid? Rosanna Wright @brockhurstlab.bsky.social @jpjhall.bsky.social &co find that #bacteria benefit from compensating plasmids by chromosomal (rather than plasmid-borne) mutations @plosbiology.bsky.social plos.io/3ODbXdN

Flagellar rotation facilitates the transfer of a bacterial conjugative plasmid @embojournal.bsky.social from Sigal Ben Yehuda www.embopress.org/doi/full/10....

www.nature.com/articles/s41...

I'm recruiting! I'm looking for a motivated postdoctoral scientist to join my new team at SCELSE in Singapore. The role will explore various aspects of how #eDNA is produced and utilised in #Pseudomonas aeruginosa biofilms. #Microsky #phagesky #Science ntu.wd3.myworkdayjobs.com/Careers/job/...

2x professorships available in Manchester Institute of Biotechnology including in Microbial Engineering area (broadly defined to include microbiomes, environmental biotech etc) — join us! www.jobs.manchester.ac.uk/Job/JobDetai...

We are looking for 2 postdocs and a technician to join our team studying evolution and development of complex flowers. Please get in touch if you’d like to discuss. Details here: www.jobs.cam.ac.uk/job/?unit=u0...

📅 Save the Date: Feb 24, 2025, at 11 AM CET! 🕚 Join our Virtual Micro-Symposium on Biofilms in Bacterial Pathogenicity, featuring insightful talks from Dr. Nicola Stanley-Wall and Dr. Jean-Marc Ghigo 🧫🔬 #Biofilms #Microbiology #Pathogenicity #VirtualEvent

Excited to share our study led by @SakenovaNazgul! We used chemical genetics to identify and understand cross-resistance & collateral-sensitivity (CS) between antibiotics and reduced AMR development with CS drug pairs @embl.org with @camille_goemans @EPFL_en www.nature.com/articles/s41...

Funded PhD available in my lab. Pls repost! www.findaphd.com/phds/project...

Extended deadline: Apply by 6th Dec for your funded early-career researcher place at our Workshop on 'Modelling Plant Stem Cells: Evolution, Development and Regeneration' Organized by @moneralee.bsky.social Kirsten ten Tussscher @renskevroomans.bsky.social www.biologists.com/workshops/ma...

go.bsky.app/sYxCv4

Jim is a great person AND does excellent science. Do apply!

The Rowe lab is recruiting a #PlantScience PhD student for 2025! You'll use our new ABACUS FRET biosensors to map the dynamic leaf #AbscisicAcid accumulations at low humidity in Arabidopsis, wheat and rice. #PhDposition www.findaphd.com/phds/project...

If you’re interested in Streptomyces, other filamentous actinomycete bacteria and their natural products follow @ActinoBase. Linked to our wiki at actinobase.org. Please share.

After a rejection, I went to my happy place: coding. The result: Cacatoo 2 is out! Cacatwo? bramvandijk88.github.io/cacatoo/ - Not just gridmodels: make flocks, shoving cells, and foraging ants. - Flocks can interact with the grid - Images/movies/output is easier to create 🧵 Examples in thread:

Open postdoc with Jill Harrison at Bristol Uni to study the evolution of apical growth Deadline 15th March Come join our HFSP funded team to investigate apical growth! thenode.biologists.com/jobs/would-y...

The next talk of the Theory of #LivingMatter online seminar will take place this week! Wednesday (21/02) at 16:00 UK. Professor Uri Alon (Weizmann Institute of Science) will give the following talk: “Simplifying inflammation and fibrosis” tlmcambridge.blog

Stochastic Models and Experiments in Ecology and Biology (SMEEB) 2024 L'Aquila, Italy from May 28th to 31st, 2024 Theory, experiment and data in microbial ecology, evolution and systems biology! Featuring @saramitri.bsky.social and @seppekuehnlab.bsky.social #evosky #livingmatter

I'm happy 😀 to announce I have a PhD position on the mathematical 🧮 modelling 💻 of microbial 🦠 evolution! I'm looking forward to working with an enthousiastic candidate on this project, please contact me with any questions! #JobAlert Please retweet! vacatures.uva.nl/UvA/job/PhD-...

Fabulous work by my colleagues - Stick'em with the pointy end ... UNLESS ...??? www.nature.com/articles/s41...

Glad to share a collaboration with Chr Hansen and PLEN (at Copenhagen University) now published in Plant Science Differential influence of Bacillus subtilis strains on Arabidopsis root architecture through common and distinct plant hormonal pathways www.sciencedirect.com/science/arti...

We did a science! Here we discussed similarities and differences in how adaptive radiations happen in bacteria as compared to animals and plants. We posit that adaptive radiations in bacteria can be kickstarted by horizontally acquired key innovations which allows lineages to invade new niches...

New in Science with @jaescudero.bsky.social . A combinatorially complete fitness landscape with >260.000 E.coli genotypes shows unexpected properties. Despite ~500 fitness peaks in this landscape, adaptive evolution can easily navigate to highest fitness peaks www.science.org/doi/10.1126/...

A rugged yet easily navigable fitness landscape -in Science from Andreas Wagner www.science.org/doi/10.1126/...

This is a phenomenal piece of work from Andreas Wagner et al - A rugged yet easily navigable fitness landscape www.science.org/doi/10.1126/... #EvoSky #MicroSky

New conference/workshop "Women in evolutionary biology" at the Max Planck Institute for Evolutionary Biology. Registration until 15 January, the event is in May 2024. 🧪👩‍🔬 #ecoevo Iink here: workshops.evolbio.mpg.de/event/102/re...

I know I am late to the party, but I like this hypothesis. Evolution (of multicellularity) as a side effect of (genome) evolution, itself a "neutral" side effect of other cellular processes, reminds me of Paulien Hogeweg's multilevel evolution theory. For example: pubmed.ncbi.nlm.nih.gov/16840361/

From James Horton (not here). James and myself have recently penned ✍️ a review article for Microbiology titled Mutation Bias and Adaptation in Bacteria: www.microbiologyresearch.org/content/jour... A short 🧵 on why we should care about mutation bias below (1/7)