Profile avatar
ethanweinberger.bsky.social
Ph.D student in Computer Science and Engineering at the University of Washington working with Su-In Lee.
13 posts 1,071 followers 349 following
Regular Contributor
Conversation Starter

Workshop on Advances in Post-Bayesian methods (May 15--16, UCL): postbayes.github.io/workshop2025/

Our new paper describing a scalable approach for training sequence-to-function models on personal genomes ("personal genome training"), includes our observations on when this works and its limitations. www.biorxiv.org/content/10.1... Congrats: Anna, @xinmingtu.bsky.social , @lxsasse.bsky.social

My heart goes out to all of the people at the NIH and CDC who were fired recently. These people weren't fired for being bad at their job or a waste of resources -- they were fired because they were easy to fire by outsiders trying to meet a quota. They worked years/decades.. for this?

Given that science funding is under attack, it might be as good a time as any to reflect on how we spend our precious dollars. Cutting out expenditure publishing papers in overpriced journals might be a good thing to seriously consider once again.

MLCB is an excellent conference and a great opportunity to meet other people in the field. Highly recommend attending!

[SAVE THE DATE] MLCB 2025 is happening Sept 10-11 at the NY Genome Center in NYC! Attend the premier conference at the intersection of ML & Bio, share your research and make lasting connections! Submission deadline: June 1 More details: mlcb.github.io Help spread the word—please RT! #MLCB2025

Mean of the training data still absolutely crushing it for perturbation prediction. www.biorxiv.org/content/10.1...

Excited to see Moscot (moscot-tools.org) published in @Nature! We scaled Optimal Transport (OT) in single-cell genomics & added multimodality together with spatiotemporal trajectory inference, finding exciting new biology in the pancreas! 🚀 Read at www.nature.com/articles/s41...

Congrats to Johannes Linder, David Kelley et al. on the journal publication of Borzoi - a long context sequence models of RNA-seq coverage profiles with many nice applications for transcriptional & post-transcriptional regulation & variant effect prediction. www.nature.com/articles/s41... 1/

Very excited to announce that the single cell/nuc. RNA/ATAC/multi-ome resource from ENCODE4 is now officially public. This includes raw data, processed data, annotations and pseudobulk products. Covers many human & mouse tissues. 1/ www.encodeproject.org/single-cell/...

The first preprint of 2025! Together with Matvei, @halfacrocodile.bsky.social, & our amazing team, we are excited to share PARADE: an AI framework for designing mRNA UTRs with enhanced cell-type specificity & stability. www.biorxiv.org/content/10.1...

Our ChromBPNet preprint out! www.biorxiv.org/content/10.1... Huge congrats to Anusri! This was quite a slog (for both of us) but we r very proud of this one! It is a long read but worth it IMHO. Methods r in the supp. materials. Bluetorial coming soon below 1/

Excited to presenting the results of my internship at insitro on modeling pooled CRISPR screening data tomorrow at the #NeurIPS2024 AI for New Drug Modalities workshop (4:30-5:10pm, West Meeting Room 109/110)! Paper: arxiv.org/abs/2411.08072 (1/n)

SPATIAL PROTEOMICS is the Method of the Year 2024!!! 🤩🤩🤩 www.nature.com/articles/s41...

Computational methods in biology opened a new world of insights and breakthroughs. 🌍 🖥️ EMBL has been at the forefront of innovations which have propelled the field forward and opened up access to bioinformatics data and resources for the entire scientific community. 🧬 www.embl.org/news/science...

🎨 In case anyone need… The NIH BioArt Source is an awesome library of *free* professionally drawn illustrations for scientific presentations or figures. Downloadable in HD. Thank you NIH for this invaluable tool 🙏! Check it out 👇 bioart.niaid.nih.gov

My goal is to understand the regulatory role of every nucleotide in the genome, and how this changes across every cell in the human body. If you are interested in doing a Ph.D. with me at UMass Chan Medical (Genomics and Comp Bio Department), see the links below. Deadline is Dec 1st.

Anybody have a bioml starter pack?