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foijer-lab.bsky.social
We study how chromosomal instability leads to cancer and try to think of clever ways to exploit chromosomal instability as a targetable vulnerability to treat cancer
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A window-of-opportunity trial reveals mechanisms of response and resistance to navtemadlin in patients with recurrent glioblastoma | Science Translational Medicine www.science.org/doi/abs/10.1...

submitted 6 days ago • 1 comment

Please check out our preprint where we find that mitotic transcription helps ensure ecDNA inheritance through chromosomal tethering: www.biorxiv.org/content/10.1...

submitted 15 days ago • 1 comment

Dear all, Postdoc positions are available to work on (1) the role of DNA strand break repair proteins during DNA replication and (2) the molecular/structural biology of XRCC1 protein complexes, as part of our work on genetic diseases & cancer. Contact me if interested: [email protected]

submitted 21 days ago • 1 comment

Supper happy to see the results of our longstanding collaboration in @naturecomms.bsky.social. We identify RBM14 as an ARGOS gene to modulate cGAS-STING signalling. Driven by @ms01.bsky.social and @vrendo.bsky.social with @bendavidlab.bsky.social and @rameenberoukhim.bsky.social. rdcu.be/d7Mky

submitted 35 days ago • 1 comment

New paper out! 🚨🥳 We thought that passenger gene amplifications can drive cancer vulnerabilities and show that RBM14 does so via cGAS-STING modulation 👇 @vrendo.bsky.social @bendavidlab.bsky.social @rameenberoukhim.bsky.social @foijer-lab.bsky.social

submitted 35 days ago • 0 comments

So excited to see our paper describing the class of ARGOS genes in cancer out in @naturecomms.bsky.social! 🤩 www.nature.com/articles/s41... A giant effort led with @ms01.bsky.social and executed under the mentorship of @bendavidlab.bsky.social @rameenberoukhim.bsky.social @foijer-lab.bsky.social 🧵👇:

submitted 35 days ago • 1 comment

High CDC20 levels increase sensitivity of #cancer cells to MPS1 inhibitors. -> www.embopress.org/doi/full/10.... High CDC20 expression promotes aneuploid cancer #cell sensitivity to #spindle assembly #checkpoint (SAC) inhibition by prolonging #metaphase and reducing mitotic errors.

submitted 40 days ago • 0 comments

CDC20 is a modulator of CIN, too much CDC20 promotes CIN, too little CDC20 decreases sensitivity to spindle checkpoint inhibitors. A very fruitful collaboration between the @bendavidlab.bsky.social and our lab. Check out our publication here: www.embopress.org/doi/full/10....

submitted 40 days ago • 0 comments

The Foijer lab is making a new start @bsky.app, moving away from X. We will continue to update you of our science news and share news of others as previously, and maybe even a bit more proactively :). Let's stay in touch!

submitted 49 days ago • 0 comments

Please consider joining us at the next EMBO Chromosome Segregation and Aneuploidy Meeting co-organised by @mcclellandlab.bsky.social @foijer-lab.bsky.social @bendavidlab.bsky.social Elsa Logarinho Dani Fachinetti and myself meetings.embo.org/event/25-ane... 🧬🔬😎

submitted 107 days ago • 0 comments

🚨Our call is open NOW! Join our PhD program in Amsterdam. Deadline: Feb. 28. Apply here: bit.ly/3O4bOjq #PhD

submitted 56 days ago • 0 comments

A great initiative to spread the use of non-mammalian models in cancer research!!!!

submitted 50 days ago • 0 comments

The Max Planck Society consists of 84 institutes worldwide. Do you want to know what they are researching? Then follow the ever-growing #MaxPlanck Family on Bluesky, share this starter pack and help people join our community 🙏 Thanks a lot! 😊 go.bsky.app/2sYoWWN

submitted 54 days ago • 1 comment

1/Delighted to announce the newest paper from our lab, “Homologous recombination promotes non-immunogenic mitotic cell death upon DNA damage”, is out today in @naturecellbiology.bsky.social, www.nature.com/articles/s41....

submitted 50 days ago • 6 comments

Announcing the next EMBO Chromosome Segregation and Aneuploidy Meeting! Italy 2025. Please register and join us for another exciting and friendly meeting in a beautiful location meetings.embo.org/event/25-ane...

submitted 110 days ago • 0 comments