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frankmenke.bsky.social
Team leader Proteomics at Sainsbury Laboratory and honorary associate Professor at University of East Anglia . Tweeting and retweeting my own views.
32 posts 1,304 followers 518 following
Prolific Poster

Wonderful to have Rosa Lozano-Durán @GeminiTeamLab University of Tübingen, back in Norwich but now giving a Friday seminar rather than sitting in the audience 😎 #CelebratingAlumni @TheSainsburyLab @JohnInnesCentre   “Hostile takeover - viral strategies to hijack a plant”

Standing room only for @metalichen.bsky.social describing our analysis of the secretome of the lichen Xanthoria parietina #ECFG17

Our phosphoproteomic analysis of appressorium morphogenesis expertly presented by ⁦Frank Menke, ‬⁩ a tour de force from Neftaly Cruz-Mireles‬⁩ and our teams. ⁦‪@TheSainsburyLab‬⁩ #ECFG17

The remarkable Starships - large mobile elements capable of moving large genomic regions in fungal populations. Changes everything we thought we knew about horizontal gene transfer among fungi and the mobility of large proportion of pan genomes ⁦‪Aaron Vogan‬⁩ #ECFG17

Its out.... Plant pathogenic fungi hijack phosphate signaling with conserved enzymatic effectors | Science www.science.org/doi/10.1126/... A wonderful collaboration with the Schaffrath @rwth.bsky.social and Oliveira-Garcia groups! Huge credit to Carl Mcombe and Alex Wegner.

Phosphorylated fungal effectors during Magnaporthe infection - a new story from Jave Bautista @thesainsburylab.bsky.social #CMINorwich25

The father of evolutionary biology, Charles Darwin, was born on this day in 1809. Happy Darwin Day!

New Publication: Preventing inappropriate signals pre- and post-ligand perception by a toggle switch mechanism of ERECTA (2025) | @frankmenke.bsky.social TSL Proteomics www.tsl.ac.uk/publications...

Beautiful night with stars #Pollock and #Castor forming triangel with #Mars, while #Jupiter shows bright closer to the horizon. #stargazing

Out today @ Science: TIR signaling activates caspase-like immunity in bacteria We report a new immune signaling molecule: N7-cADPR. Produced by phage-induced TIRs and activates a defensive bacterial caspase Congrats Francois Rousset, Ilya Osterman and coauthors! www.science.org/doi/10.1126/...

New MAMP from nematodes (derived from a peptide of trehalase), is also found in insects and fungi. Plant immune responses require lectin receptor kinases - LecRK-Vs. Cool! I like the old-school protein biochem for MAMP ID. 🙂 #PlantPathogenInteractions #PlantScience www.biorxiv.org/content/10.1...

📜 Endogenous RALF peptide function is required for powdery mildew host colonization 🧑‍🔬 Henriette Leicher, Martin Stegmann, et al. 📔 @biorxiv-plants.bsky.social 🔗 www.biorxiv.org/content/10.1... #️⃣ #PlantScience #PlantImmunity

🚨BREAKING. From a program officer at the National Science Foundation, a list of keywords that can cause a grant to be pulled. I will be sharing screenshots of these keywords along with a decision tree. Please share widely. This is a crisis for academic freedom & science.

Great to have @NeftalyCruzMireles (not at Bluesky yet)back at @thesainsburylab.bsky.social, if only for a day

Our study on #lichen #symbiosis is out in @currentbiology.bsky.social! How can multiple microbes create a large, 3D, and structurally complex organism? To answer this question, we used #metagenomics, #metatranscriptomics, and a bit of protein structure modeling 🧵1/7 🧬 🖥️ 🧪 🦠 🧫 #SymbioSky

Looking forward to @thesainsburylab.bsky.social and @johninnescentre.bsky.social Friday seminar on NLR-related proteins in bacterial immunity by @aaronwhiteley.bsky.social

🌱Jessica Trinh, Megann Tran and @gittacoaker.bsky.social discussed the ways vector-borne bacterial pathogens evade plant immunity with fewer and less immunogenic MAMPs than free-living relatives, highlighting co-evolutionary adaptations. ▶️ bsppjournals.onlinelibrary.wiley.com/doi/full/10....

DIA-NN 2.0 is released! We consider it the biggest step forward in the history of DIA-NN. On modern LC-MS almost all identifications are now peptidoform-confident, with major improvements e.g. for phospho. Some other cool things too: github.com/vdemichev/Di...

IS-MPMI 2025 abstract submission is open! Submit to our concurrent session "Spatial & Temporal Resolution of the Interaction Interface" if your research explores heterogeneity or spatiotemporal dynamics in plant-microbe interactions. Due March 11. See you in Cologne! www.ismpmi.org/Events/2025C...

📣 #PlantBio2025 Plenary: Molecular Exchange Between Plants and Their Interacting Microbes.🌱 Learn more and register now! 👀 https://plantbiology.aspb.org/plenary-symposia/ 👉 Early Bird rates end March 19! Hurry and register soon for the best savings. #PlantScience

Ten simple rules for developing good reading habits during graduate school and beyond journals.plos.org/ploscompbiol...

2️⃣ goals 1️⃣ assist 👏 Cody is your #LIVIPS Player of the Match 🏆

Born #OnThisDay in 1885 was Marjory Stephenson FRS, the famed biochemist and one of the first two women to be elected to the Royal Society, 80 years ago this March. Stephenson also founded the Microbiology Society and served as its second president. #HistoryOfScience #WomenInSTEM

Born #OnThisDay in 1627 was Robert Boyle FRS, Royal Society founder and regarded as one of the first modern chemists. Boyle also wrote a wish list of what he hoped could be achieved through science, including things like 'Attaining Gigantick Dimensions'. What would you like to see science achieve?

📜 A pair of LysM receptors mediates symbiosis and immunity discrimination in Marchantia 🧑‍🔬 Xinhang Tan, Dapeng Wang, Ertao Wang, et al. 📔 Cell 🔗 www.cell.com/cell/fulltex... #️⃣ #PlantScience #PlantEvoDevo #PlantEvoMPMI #Marchantia #PlantSignaling #PlantEvolution

Great to welcome @pierremarcdelaux.bsky.social to @johninnescentre.bsky.social and @thesainsburylab.bsky.social today - fascinating insights into plant symbiosis and immunity

Highlighting the amazing work of @puginiercamille.bsky.social on algal evolution and the lichen symbiosis. @pierremarcdelaux.bsky.social @johninnescentre.bsky.social @thesainsburylab.bsky.social

📜 Preventing inappropriate signals pre- and post-ligand perception by a toggle switch mechanism of ERECTA 🧑‍🔬 Liangliang Chen, @frankmenke.bsky.social, @keikoutorii.bsky.social, et al. 📔 @pnas.org 🔗 pnas.org/doi/10.1073/... #️⃣ #PlantScience #PlantDevelopment #PlantSignaling

Today’s @thesainsburylab.bsky.social and @johninnescentre.bsky.social Friday seminar is @pierremarcdelaux.bsky.social presenting #evolution of #plant #microbe interactions

#plantproteolysis2025

Winterwalk at @rspb.bsky.social Strumpshaw fen and Buckenham mash. Flocks of Widgeon and Lampwing feeding in the grass and Marsh harriers overhead sending huge numbers up in the air.

He knows what he is doing, and getting away with, for now.

From lesions to lessons: 2025 marks the 20th anniversary of filamentous plant pathogen genomics. In our new review, we present lessons we learned over the past 2 decades and discuss the future of plant pathogen genomics. Take a first look! apsjournals.apsnet.org/doi/10.1094/...

Welcome to @HazelSurtees.bsky.social who joins the @TheSainsburyLab.bsky.social #Proteomics team on her second rotation to investigate PSK-induced changes to Arabidopsis proteome with @draegermarkus.bsky.social

www.nature.com/articles/s41... See our new review in Cell Death and Differentiation led by Matthew Wengler on regulated cell death in Magnaporthe @thesainsburylab.bsky.social

New year, new paper! Now published in @nature.com. We identified and characterised diverse immune cell states in plants under pathogen attack. My postdoc work in the Ecker lab at @salkinstitute.bsky.social. A thread (0/n) #PlantScience www.nature.com/articles/s41...

Do you know these three Russian agronomists? If you're interested, you're in for a real #ScienceDrama in four acts! 🧪🎭 Their story is the central piece of my Short History of Vernalization, but let me tell you about them here: 👇🧵🧵🧵🧵 #PlantScience #ScienceHistory

Happy New Year, everyone! Our lab welcomes 2025 with a revised @biorxiv-plants.bsky.social preprint of our temperature-plant systemic immunity study, which started as a MSc thesis project of former graduate student Alyssa Shields @laurierbiology.bsky.social. www.biorxiv.org/content/10.1...

Thrilled to share our work on an unusual EXO70 clade unique to grasses and grass-like species 🌾! (1/8) www.biorxiv.org/content/10.1... @thesainsburylab.bsky.social

Head into next week with the confidence of a crow. 🪶

Lab-made ‘mirror bacteria’ could endanger all life on earth, scientists warn www.independent.co.uk/news/science...

📄New Publication: Can AI modelling of protein structures distinguish between sensor and helper NLR immune receptors? @amiralito.bsky.social Frijters R, @tolgaboz.bsky.social Terauchi R @kamounlab.bsky.social @yusugihara.bsky.social www.biorxiv.org/content/10.1... www.tsl.ac.uk/publications...

Arabidopsis WALL-ASSOCIATED KINASES are not required for oligogalacturonide-induced signaling and immunity

Chih-hang Wu, Ladies & Gents: www.embo.org/people/insig...