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gavsturm.bsky.social
mitochondria, generative modeling, cellular aging, blender, procedural generation, complex systems theory. @WallaceMarshall @UCSF @mitopsychobio
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In regular microscopy we image 2D objects to 2D images. However, a 'remote refocus' (RR) can image 3D objects to 3D images! -> Here's a tiny 3D object imaged by RR. The 3D image 'floats' in the remote space, and can be reimaged in different ways. -> This is the foundation of some new technologies!

submitted 10 days ago • 0 comments

The end of an era. After 9.5 years the York lab departs Calico with an incredible roster of projects and publications: andrewgyork.github.io -> It's been an honor to be part of this team and I wish @mariaingaramo.bsky.social & @andrewgyork.bsky.social the best on their new journey! What a ride ;)

submitted 12 days ago • 6 comments

For those who aren't biologists: This is a biosafety cabinet. Every biomedical research lab in the country has one or more of these bio safety cabinets. They use air flow to protect cells from contamination by bacteria and fungal spores while you are working with them.

submitted 14 days ago • 4 comments

Microscopy Nodes is now up on bioRxiv! 🚀 This is a Blender extension that seamlessly integrates and visualizes 3D microscopy data (TIF & @zarr.dev). High-quality volume rendering for anyone, in both EM and fluorescence, regardless of computational expertise! 🔬 www.biorxiv.org/content/10.1...

submitted 42 days ago • 9 comments

Mitochondria consist of networks of cylindrical tubes, right? Not necessarily! - in our new preprint, @gavsturm.bsky.social investigates how mitochondria transiently adopt a beads-on-a-string morphology www.biorxiv.org/content/10.1...

submitted 65 days ago • 6 comments

I’m ultra excited about our preprints on mitochondrial pearling. In two concurrent collaborative studies with @wallaceucsf.bsky.social, we investigated its consequences on mtDNA nucleoids (led by @jclandoni.bsky.social) & its biophysical causes (led by @gavsturm.bsky.social). Funders HFSP, ERC, SNSF

submitted 65 days ago • 2 comments

2x Preprint drop!!! Mitochondrial pearling has arrived! “The Biophysical Mechanism of Mitochondrial Pearling”. “Pearling Drives Mitochondrial DNA Nucleoid Distribution” 1/10 www.biorxiv.org/content/10.1... www.biorxiv.org/content/10.1...

submitted 65 days ago • 3 comments

Delighted to share our new preprint on the cell biology and genome of Stentor pyriformis, a giant ciliate that maintains Chlorella endosymbionts in surface-associated microtubule baskets. www.biorxiv.org/content/10.1...

submitted 67 days ago • 12 comments

Think mitochondria are networks of cylindrical tubes? not always! Check out poster by @gavsturm.bsky.social "Mitochondrial Pearling: an emerging class of organelle dynamics explained by a biophysical pearling instability" tomorrow Sunday Dec 15 11:45-12:45 B145

submitted 74 days ago • 2 comments

I know slow sadness. I've known loud sadness. Sadness like a blanket wrapped around your shoulders, your heart. I was not expecting this panic. This otherworldly sense of wrongness. The urgent feeling that this wasn't how it was supposed to go. Bereavement.

submitted 76 days ago • 5 comments

Non-comprehensive list of projects, hardware, software, and people related to #OpenMicroscopy. List could do with some updates, so please share and suggest additions! github.com/HohlbeinLab/...

submitted 79 days ago • 0 comments

Continuing to go through my trove of cool videos... here is a classic from my work with Philipp Keller's team at @hhmijanelia.bsky.social A developing fly embryo imaged with a SiMView #lightsheet microscope augmented with our Autopilot self-alignment system. www.nature.com/articles/nbt... 🧪🔬🪰💻

submitted 79 days ago • 4 comments

Excited to share our latest findings, now published @NatureNeuro www.nature.com/articles/s41... We found unmyelinated axons exhibit pearls-on-a-string morphology's due to their membrane mechanical properties. Threads will follow!

submitted 87 days ago • 20 comments

GFAP expressing #astrocytes in orange, IBA1 positive microglia in blue. Images from unsectioned rat hemisphere. #lightsheet #microscopy at #Vanderbilt

submitted 100 days ago • 4 comments

Dense microtubule networks resolved with Airyscan for #MicroscopyMonday 🔬

submitted 93 days ago • 1 comment

Starting brand new on this platform, it's not to late to try our tool 'da_tracker', designed for quantitative single cell and single phagosome tracking, using PyImageJ, and Trackmate-Cellpose (So it's free): journals.biologists.com/bio/article/... Feel free to reach out if you need help to try it !

submitted 97 days ago • 1 comment

Some more Blender GeoNodes simulations... this time with mitochondrial-ER interactions!

submitted 102 days ago • 0 comments

Starting up Bsky with some of my favorites... Hope this helps support the big move!

submitted 102 days ago • 1 comment