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gchiduza.bsky.social
Chargé de recherche @ulbruxelles.bsky.social interested in transporters and protein-lipid interactions in autism and autophagy. @crick.ac.uk alumnus. #membrane #proteins #biochemistry #cryoEM #structuralMS
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Structural biology is in an era of dynamics & assemblies but turning raw experimental data into atomic models at scale remains challenging. @minhuanli.bsky.social and I present ROCKET🚀: an AlphaFold augmentation that integrates crystallographic and cryoEM/ET data with room for more! 1/14.

Another day another structural biology AI based tool 😎

Towards community-driven visual proteomics! Excited to finally share this large-scale curated & annotated dataset of 1829 high-quality #cryoET tomograms of the little green alga that just keeps giving— Chlamydomonas! 🧪🧶🧬🌾🌊🌍 Preprint📜: www.biorxiv.org/content/10.1... A short thread🧵👇

We are currently advertising our AI #ionchannel modelling PhD Studentship. Fully funded (sadly only for UK based students). Please repost or mention to any potential victims hmmmm, *applicants* you know? www.findaphd.com/phds/project... Richardbj.bsky.social

1/ A new series of #CryoSPARC tutorial videos from this year’s S2C2 #cryoEM image processing workshop are now online! These videos will be interesting to all users and especially those newer to #cryoEM. www.youtube.com/playlist?lis...

I have received a Wellcome Discovery Award to study the initiation of eukaryotic DNA replication, with 8 years of funding at the Francis Crick Institute. Looking for a postdoc in molecular mechanisms, cryo-EM, cryo-FIB and in situ structure? Contact me now! 3 postdoc positions advertised soon.

One of those #cryoEM papers were using "near-atomic resolution" in the title would be entirely ok. 😉 academic.oup.com/nar/advance-...

High-resolution template matching of the human ribosome in situ by Lippincott-Schwartz Lab @hhmijanelia.bsky.social @hhmi.bsky.social. >40 conformations within together reveal molecular dynamics of the elongation cycle with previously unknown bending and “spring-like” motion.

I am about to be recruiting two post-docs to work on cryoEM and cryoET of amyloid aggregates... Anyone interested please drop me a line while the wheels of our HR department turn.............

I am super excited to share our latest work on the native in-cell organization of the mitochondrial respiratory chain 🥳 Using cryo-electron tomography 🔬, we show how the respiratory complexes (and other complexes) are organized inside native mitochondria!  www.biorxiv.org/content/10.1...

My first post on Blue Sky - moving over ! For all post-docs out there - fantastic opportunity @EMBL. Independent group leader position: Core funding, state-of-the-art core facilities, access to fantastic Ph.D. students, and of course amazing colleagues. Please apply www.embl.org/jobs/positio...

An AF3-like model available with an MIT license “Our model and code are released under MIT License, and can be freely used for both academic and commercial purposes.”

Proud of new work tinyurl.com/yhz4c6ry from the lab by Zhicheng (Chen) Cui using single-particle cryo-EM on liposomes to show how mTORC1 integrates nutrient and growth factor signaling at lysosomes, collab. w/ G. Napolitano,A. Esposito, and A. Ballabio.

First bluesky post! About time. This week, our manuscript revealing the structure, inhibition, and mechanism of human Ceramide Synthase 6 was finally published in NSMB. We combined cryo-EM and mass spectrometry to reveal its ping-pong mechanism. Check it out! doi.org/10.1038/s415...

As my lab's first post on Bluesky. If you are a UK Structural Biologist please come to our one day meeting on Friday 6th December Lots of talk slots to be selected from abstracts. Deadline for abstracts is TOMORROW: Friday 15th Nov. bit.ly/4fDEqfZ

Just recently moved from X/twitter