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gchojnowski.bsky.social
I build EM and MX models and write software to make it a bit less of a hassle. Some of the code I wrote is a part of CCP4 and CCP-EM. https://gchojnowski.github.io
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Today marks the 82nd anniversary of the Warsaw Ghetto Uprising, recognized as the largest act of armed resistance undertaken by Jews during WWII. Launched against insurmountable odds, the rebellion is often cited as one of the defining moments in modern Jewish history.

www.goodreads.com/quotes/99381... a grim reflection on the past and a projection of the future that has just arrived.

Finally!

High time to understand what's going on in there. Sadly, the historian's perspective is as depressing as that of Faulkner, Steinbeck or Bukowski.

I’m happy to share gapTrick, an AlphaFold2-based tool for characterising protein-protein complexes www.biorxiv.org/content/10.1...

The book doesn't really explain why we sleep, but the message is very simple and convincing: "Go the f*k to sleep!". Highly recommended (the book too).

This might be a good opportunity to remind people that experimental data (diffraction or cryoEM maps) have to be provided with the submission of papers to the IUCr society journals on Structural Biology, Acta Cryst D and F. So referees don’t even have to ask any more!

We have released version 2 of AlphaPulldown - a general pipeline for high-throughput structural modeling! Software: github.com/KosinskiLab/... Preprint: biorxiv.org/content/10.1...

EMBL is Europe’s life sciences laboratory. 🧬🧪 At our sites in Barcelona,​​ Grenoble, Hamburg, Heidelberg, Hinxton, and Rome, we seek to understand life in context, from molecules to ecosystems. 🔬🌍 Follow us for our latest news and updates about research, training, services and more. www.embl.org

Really looking forward to welcoming & meeting the participants of our #EMBOStructBio course this morning! Many of our speakers/tutors are here: @moalquraishi.bsky.social @sykhalid.bsky.social @ezgikaraca.bsky.social @amjjbonvin.bsky.social @gchojnowski.bsky.social @drmelissagraewert.bsky.social

New GPU-based MMseqs2: 20x faster searches on a single L40S (approx. as fast as a RTX 4090) vs. a 128-core CPU. This work enables to set up a very cost-efficient ColabFold MSA GPU server. 🧵🧵 📄 www.biorxiv.org/content/10.1... 💾 mmseqs.com 🗞️ developer.nvidia.com/blog/boost-a...

How many of the PDB models that were solved using experimental phasing could have been solved by molecular replacement using models obtained from AlphaFold? #MolecularReplacement #AlphaFold2 #ComputationalMethods t.co/s6EahtcYms