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geneontology.bsky.social
The Gene Ontology (GO, geneontology.org) knowledgebase is the world’s largest source of information on gene function. Our mission is to develop a comprehensive, computational model of biological systems, ranging from the molecular to organism level.
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You know about the PAN-GO #Functionome, but have you explored the power of the Functional Category search? Learn how to find #humangenes of interest in just a few clicks, using the Functional Categories community.alliancegenome.org/t/8362 🧬🧪 #GOSlims ICYMI: community.alliancegenome.org/t/8343

submitted 18 days ago • 0 comments

The PAN-GO #Functionome was announced last week in @nature.com-but do you know how to use it? Here's how to find functions for a selected human #gene: ➡️ community.alliancegenome.org/t/8353 ICYMI, more on the PAN-GO Functionome: 💡 community.alliancegenome.org/t/8343 🧪🧬 #science #research #human

submitted 27 days ago • 1 comment

THE PAN-GO #FUNCTIONOME IS LIVE! Read our brand new #openaccess @nature.com paper and explore the PAN-GO Functionome, our most accurate and complete resource ever! Paper links, press release, how to contribute and more on the @alliancegenome.bsky.social Forums: community.alliancegenome.org/t/8343

submitted 32 days ago • 1 comment

Is that love in the air? Yes! You'll LOVE this news- the February 2024 GO Release [2025-02-06](release.geneontology.org/2025-02-06/i...) is now available! [http://release.geneontology.org/2025-02-06](release.geneontology.org/2025-02-06) [10.5281/zenodo.14861039](doi.org/10.5281/zeno...)

submitted 44 days ago • 1 comment

The Spring 2025 GOC Meeting will be May 6-8 in Geneva! Will you be there? Registration details were sent out to all GOC members, check your email!

submitted 46 days ago • 0 comments

Wishing everyone a safe and happy holiday season! Although our downloads and products should be available over the break, we will not have any staff available to address any enquiries until January 5th. We look forward to seeing you all when we return in January 2026!

submitted 100 days ago • 0 comments

It's time to start thinking about New Year's Resolutions. But what's one of the easiest ways to be healthier in the New Year? Why, by making sure your GO data is healthy! Read more on the @alliancegenome.bsky.social forum: community.alliancegenome.org/t/go-start-t...

submitted 114 days ago • 0 comments

It's getting chilly; a familiar scent is in the air- but it's not pumpkin spice, it's the smell of a fresh new GO Release! The Nov GO Release is out in the wild & ready to party! current.geneontology.org release.geneontology.org/2024-11-03 Full deets: community.alliancegenome.org/t/november-2...

submitted 138 days ago • 1 comment

Did you know there are different ontology files, and the relations (and tool compatibility) varies between them? Read more on the @alliancegenome.bsky.social Forums: community.alliancegenome.org/t/relations-...

submitted 149 days ago • 0 comments

GO traditionally focused on protein-coding genes, but a new publication by Antonazzo et al. highlights the recent expansion of ncRNA annotation. Definitely worth reading for both researchers and curators! community.alliancegenome.org/t/expansion-...

submitted 164 days ago • 0 comments

❓ GO puts the FUN in function, yes - but what is phenomenal for phenomics??? ➡️ uPheno! Read more about the fantastic Unified Phenotype Ontology here: community.alliancegenome.org/t/ever-neede...

submitted 172 days ago • 1 comment

Attention GO Consortium members: if you haven't yet registered or submitted topics of interest for the October GOC meeting, time is running out! Check your emails or the GO Wiki for links. GOC Fall 2024 Meeting is Tuesday, Oct 15th- Thursday, Oct 17th & will be virtual.

submitted 184 days ago • 0 comments

Welcome all new users! It's not just 🦋 that's rapidly gaining users-the @alliancegenome.bsky.social is too! The Alliance, of which GO is a founding member, will have a live webinar on September 19th: An Introduction to the Alliance". Register by Sep 18th! community.alliancegenome.org/t/webinar-an...

submitted 207 days ago • 0 comments

Ever see a #GeneOntology annotation that doesn't use a PMID as a reference, but instead has GO_REF: and a bunch of numbers? Find out what a GO_REF is & where to find full descriptions of them in this week's Alliance Forums post: community.alliancegenome.org/t/whats-a-go...

submitted 212 days ago • 0 comments

Do you work with chicken data? Do you know about GEGA, and how it combines GO with other database information? Read more at the @alliancegenome.bsky.social forums: community.alliancegenome.org/t/gega-gallu... Access GEGA at gega.sigenae.org

submitted 219 days ago • 0 comments

Lead contamination is a danger to us all. Even if you test your water, it can still be in the food you eat. Han et al. identify flavonoid metabolism as important in the response to lead stress in maize- more at @alliancegenome.bsky.social Forums: community.alliancegenome.org/t/go-and-lea...

submitted 240 days ago • 0 comments

Cancer research progresses every day. In a new paper from Huang et al, there is a novel prognostic signature that may help predict immunotherapy response- and they use GO to help their research: community.alliancegenome.org/t/go-and-lun...

submitted 248 days ago • 0 comments

Most #GeneOntology annotations propagate up the #ontology- but do you know how to identify ones that do NOT? Read more on the @alliancegenome.bsky.social Forum: community.alliancegenome.org/t/transitivi...

submitted 254 days ago • 0 comments

Do you use GO GPAD files? Although mostly used for internal purposes, if you use GPAD files please be aware the format is getting an update to GPAD 2.0 and this is a breaking change. Details at community.alliancegenome.org/t/go-file-fo...

submitted 261 days ago • 0 comments

Liquorice can be divisive-some love it, others hate it. However, it has known medicinal qualities. Ma et al. use #GO (and #omics) to evaluate the potential #medicinal value of a rare wild liquorice and show the importance of preserving #biodiversity 🧪 community.alliancegenome.org/t/go-and-rar...

submitted 263 days ago • 0 comments

Forgot to register for Quest for Orthologs 2024? Registration AND abstract submission dates have been extended to May 14!! Act now and join QFO8 in Montreal this July 17-18, right after ISCB's ISMB: event.fourwaves.com/qfo8/pages

submitted 326 days ago • 0 comments

Don't be the weak link! If you link to GO terms, GO_REFs, GO-CAMs, or the ontology, make sure you're using PURLs. Read more: community.alliancegenome.org/t/best-pract... 🧪

submitted 328 days ago • 0 comments

Best way to celebrate #itsgonnabemay? A bonus GO release to wrap up April! Details for the new, second April release (2024-04-24): 🧪 community.alliancegenome.org/t/second-apr...

submitted 334 days ago • 0 comments

Holy Pathways, Batman! Did you know you can find GO-powered Pathways on @alliancegenome.bsky.social pages? community.alliancegenome.org/t/go-cams-on...

submitted 335 days ago • 0 comments

Happy #DNADay2024! 🧬 Today's @alliancegenome.bsky.social forum post highlights some of the close ties between the Human Genome Project and the #GeneOntology: both Dr. David Botstein and Dr. Paul Thomas. community.alliancegenome.org/t/happy-dna-... 🧪

submitted 339 days ago • 0 comments

Rice, wheat, bamboo, maize... the Poaceae family is immense. Read the new Nature Communications publication that looks at WGD in the massive grass family: #wholegenomeduplication 🧪 community.alliancegenome.org/t/go-and-who...

submitted 340 days ago • 0 comments

Ever try to look up a term in AmiGO, but the results included extra terms? That's a feature not a 🐞! Read about how we use closures to show you ontology search results- and how you can restrict this if needed 🧪 community.alliancegenome.org/t/tuesdaytip...

submitted 341 days ago • 0 comments

New GO release! 2024-04-18 is available now! current.geneontology.org release.geneontology.org/2024-04-18 10.5281/zenodo.10999780 🧪 42,271 GO terms 7,668,043 annotations 1,536,109 gene products 5,404 species More info & release notes: community.alliancegenome.org/t/april-2024...

submitted 342 days ago • 0 comments

It's now more crucial than ever to cite resources you wish to keep using- GO, @alliancegenome.bsky.social, etc. In addition to citing these references, GO asks users/tool devs/etc. to include the GO Release. Does GO really change that much?... Yes! 🧪 community.alliancegenome.org/t/archive-of...

submitted 346 days ago • 0 comments

Today's paper highlight: new Scientific Reports publication that uses #GeneOntology and could help advance research on liver cancer #CancerResearch 🧪 community.alliancegenome.org/t/go-and-hep...

submitted 347 days ago • 0 comments

#TuesdayTips: Did you know there's a free #OpenAccess GO Handbook? We're highlighting the first chapter, which is an overview of #ontologies in general: 🧪 community.alliancegenome.org/t/go-handboo...

submitted 348 days ago • 0 comments

Sugar: eating it is easy... studying the ~9Gb sugarcane genome, not so easy. Read how Bao et al. assembled the ultra-complex modern hybrid sugarcane genome, and how GO helped identify important genes community.alliancegenome.org/t/go-and-hyb... 🧪🌾

submitted 352 days ago • 0 comments

Quest for Orthologs 2024: if orthology predictions are your thing, you need to be in Montreal this summer! 🧪 Meeting info: ➡️ QfO-8 website: event.fourwaves.com/qfo8/pages 📣 Sharable meeting announcement: community.alliancegenome.org/t/quest-for-...

submitted 353 days ago • 0 comments

GO is meant to be computer readable- but do you know anything about the group of people that maintain the GO knowledgebase? community.alliancegenome.org/t/the-people... 🧪

submitted 355 days ago • 0 comments

Application deadline for 2024 #Yeast #Genetics and #Genomics Course has been extended to April 22! Significant financial aid may be available for trainees applying, covering up to 50% of the cost of the course - check it out! community.alliancegenome.org/t/deadline-e...

submitted 355 days ago • 0 comments

We are tweaking some things behind the scenes so our GO releases were delayed- but we now have a fresh new release! 🧪 community.alliancegenome.org/t/march-2024... release.geneontology.org/2024-03-28

submitted 356 days ago • 0 comments

Ever noticed the GO annotation sets you see in AmiGO (amigo.geneontology.org ) are different than QuickGO (ebi.ac.uk/QuickGO ) ? They're all correct, but (mostly) depend on the entity being annotated: 🧪 community.alliancegenome.org/t/go-amigo-v...

submitted 359 days ago • 0 comments

GO is all about gene function, so can it be helpful in work that examines PTMs? Certainly! Read more about the PTM profiling of CCCTC-binding factor and what that means for 3D chromatin structure: community.alliancegenome.org/t/go-and-ptm...

submitted 360 days ago • 0 comments

New user interface for YeastMine (same data!) We have updated YeastMine to use the new BlueGenes user interface from InterMine. The new interface provides the same functionality, more interactive experience for exploring and analysis. www.yeastgenome.org/blog/new-use...

submitted 360 days ago • 0 comments

GO enrichment, GO analysis, GSEA, function enrichment, and sometimes people just call it "GO" . Whatever you call it, when you need term enrichment, use the official GO tool from PANTHER: 🧪 community.alliancegenome.org/t/go-enrichm...

submitted 361 days ago • 0 comments