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genophoria.bsky.social
Core Investigator @ Arc Institute | Associate Professor @ UCSF | {Computational, Systems, Cancer, RNA} biologist | Co-founder @exaibio @vevo_ai
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Exciting dataset! If you're looking for a complimentary scRNA-seq drug perturbations in healthy/primary tissue (PBMCs), check out our dataset with ~36% # drugs of Tahoe. proceedings.neurips.cc/paper_files/...

submitted 1 day ago • 0 comments

AI 🤝 Biology Tahoe-100M, the largest single cell dataset ever generated, has just been open-sourced as part of the @arcinstitute.org Virtual Cell Atlas Initiative in partnership with @vevotherapeutics.bsky.social We're excited to see how this transforms the use of AI in biology!

submitted 1 day ago • 0 comments

It is always exciting when I have to adjust the y-axis limits of this plot, but extra special this time having been part of this project at @vevotherapeutics.bsky.social! tinyurl.com/vevo-tahoe100

submitted 1 day ago • 0 comments

for heart month, a nice little piece on what we do at Gladstone for the heart gladstone.org/news/matters...

submitted 1 day ago • 2 comments

At the @arcinstitute.org we are building AI models of cell state from the ground up, rethinking every step, from data generation to biologically relevant evaluation Today we launch scBaseCamp, the largest public repository of single cell RNAseq data, uniformly processed from raw sequencing reads.

submitted 1 day ago • 1 comment

Today, we're launching the Arc Virtual Cell Atlas, a growing resource for computation-ready single-cell measurements. arc-website-git-ben-virtual-cell-atlas-tool-arc-institute.vercel.app/news/news/ar...

submitted 1 day ago • 1 comment

Watch @thejohnnyyu.bsky.social @therealnima.bsky.social (@vevotherapeutics.bsky.social), @pdhsu.bsky.social , Dave Burke and I (@arcinstitute.org) talking about virtual cells, and how #Tahoe100M, now on. @arcinstitute.org's Virtual Cell Atlas, can change the game! www.youtube.com/watch?v=ak_f...

submitted 1 day ago • 0 comments

Calling attention to this tome. 👀 By reading this paper, you are likely to learn many things, not the least of which is that using "Giga-scale" in your paper title sounds bad-ass. Worked headed by @genophoria.bsky.social & @vevotherapeutics.bsky.social #genomics #bioinformatics 🧪 bit.ly/4bj2fIc

submitted 2 days ago • 0 comments

@thejohnnyyu.bsky.social, @therealnima.bsky.social, and I, are excited to tell you about Tahoe-100M! The largest publicly available single-cell dataset that measures the effect of 1200 genes on 50 cell line models. The Vevo team has outdone itself. #Tahoe100M www.biorxiv.org/content/10.1...

submitted 1 day ago • 1 comment

I love this insight on building teams from @genophoria.bsky.social, Core Investigator at Arc Institute, which just released Evo 2: the largest AI model for biology to date. Catch the full conversation: + YouTube: youtu.be/sWcoslBueiE + Spotify: spoti.fi/4hLk3xo + Apple Podcasts: apple.co/40sQCu9

submitted 6 days ago • 0 comments

Evo 2 is the kind of project that can only be done at a place like @arcinstitute.org, and with partners like NVIDIA. If you are intrigued by what we are building at the intersection of AI and Biology, come join our AI team at Arc.

submitted 7 days ago • 0 comments

A thread. Things are bad. But we’ve already lost if they smother the passion & joy we have for science. So here’s a proposal: if you’re a biologist in any way impacted by *exasperated wave* & want to chat, drop me an e-mail at myfirst.mylast[at]ucsf.edu. Let’s schedule a 30min chat about [...] (1/n)

submitted 9 days ago • 2 comments

@science.org RNA polymerase II at histone genes predicts outcome in human cancer 🧬💊 @fredhutch.bsky.social @hhmi.bsky.social www.science.org/doi/10.1126/...

submitted 10 days ago • 4 comments

Please everyone call your representative and senators right now!! Try local offices. We all need to do this - they are buried with things I know but this one will wipe out science in the US

submitted 19 days ago • 0 comments

Check out our new preprint: Network-aware self-supervised learning enables high-content phenotypic screening for genetic modifiers of neuronal activity dynamics Project led by @parkergrosjean.bsky.social - see his "blue-torial" below!

submitted 20 days ago • 0 comments

"Imagine a DAPI-like stain, but for the extracellular matrix." That's basically how this work was pitched to me by Kayvon and Antonio a year or so ago. Now the final product really delivers. Read about their versatile label for ECM in living tissues here: www.nature.com/articles/s41...

submitted 20 days ago • 9 comments

This year, miRNAs won the Nobel Prize—small non-coding RNAs (smRNAs) have arrived! But the biology of many smRNAs remains a mystery. With Decoy-seq, we’re bringing smRNA genetics into the new decade. @hsnajafabadi.bsky.social www.biorxiv.org/content/10.1...

submitted 29 days ago • 1 comment

Check out this tweetorial from @vram142.bsky.social and while you’re at it, reach out to your representatives to get NIH back to work…

submitted 34 days ago • 0 comments

Vevo Therapeutics 💙 NVIDIA Healthcare 💙 Open Source. And we love making history with other like-minded organizations. Thanks Parse Biotechnology for GigaLab, without which this would not have been possible. And to Ultima Genomics for the support. Press Release: www.prnewswire.com/news-release...

submitted 42 days ago • 0 comments