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Less than half an hour for the next Africa-Europe Seminar where Prof Hilary Ranson and Prof Charles Wondji discuss the use of genetics to guide the control of mosquitoes that transmit malaria in Africa!

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Stemming from discussions at a recent CSHL Banbury meeting on NF1, this Perspective by Gutmann et al. highlights the current approaches, challenges and future directions to improve patient health and outcomes. #OpenAccess Read the Perspective here: ➡️ tinyurl.com/gd352629

submitted 5 days ago • 0 comments

In this Review, Van Alstyne et al. discuss everything Tau, including the pathogenic mechanisms of neurological tauopathies and advances in tau targeted therapies. Learn more here: ➡️ tinyurl.com/gd352551

submitted 7 days ago • 0 comments

🚨We’re proud that The Genetics Society @gensocuk.bsky.social supports the upcoming UK EvoDevo meeting. Register for only £5 and submit your abstracts before June 1st! Link to register: eshop.qmul.ac.uk/conferences-...

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We are happy to announce student and postdoc speakers. Thanks to all who submitted an abstract! #yen2025

submitted 8 days ago • 1 comment

Continuing the recent theme of conservation genetics, we return to the sea with Marc Gose and Rob Ogden. They discuss their work on the white-beaked dolphin, and the importance of international collaboration to manage populations that span borders @gensocuk.bsky.social @edinburgh-uni.bsky.social

submitted 9 days ago • 1 comment

Last week we hosted our #Epigenetics2025 conference. Congratulations to @thomasbalan.bsky.social, Jasmina Al-Mousawi & Georgia Lee on winning best poster prizes! And a HUGE thank you to the organisers: @yatlasi.bsky.social, Michelle Holland, @adrianbracken.bsky.social & @labrowe.bsky.social

submitted 12 days ago • 0 comments

Have you heard? We’re accepting abstracts for #ASHG2025! Submit your science and join us in Boston. www.ashg.org/meetings/202... @geneticssociety.bsky.social @gensocuk.bsky.social

submitted 13 days ago • 0 comments

I add an amazing time last week at the Epigenetics 2025 meeting from the @gensocuk.bsky.social in sunny Belfast! Great discussions and insights on my PhD project! Also very honored to have been awarded the best poster prize!

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📢Tell us what you think about the Node and help us shape the Node's future! Please spare around 5 minutes to fill in our survey: www.surveymonkey.com/r/7QHYQCW Participants of the survey can enter a prize draw for a chance to win a bag of goodies from @biologists.bsky.social 🎁 #DevBio #StemCells

submitted 13 days ago • 0 comments

The next online Africa-Europe #genetics #genomics seminar will focus on mosquitoes that vector malaria. It features Hilary Ranson from ‪@lstmnews.bsky.social‬ & Charles Wondji and will be held on May 13. Register for free access using the link in the flyer below!

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Big congratulations to Prof. Kathy Niakan on receiving the 2025 Mary Lyon Medal from the Genetics Society UK in recognition of her outstanding research in genetics and developmental biology @niakanlab.bsky.social @gensocuk.bsky.social

submitted 18 days ago • 0 comments

Thank you to @gensocuk.bsky.social and all organisers for a wonderful meeting- amazing range of topics, excellent talks and really fun QandA sessions. Only problem is that I'm going back home with too many ideas for new experiments!

submitted 18 days ago • 1 comment

What a fantastic meeting and forum to discuss our latest research! Special focus on enhancer function, chromatin modification and how 3D folding of chromatin impacts enhancer action. All in the context of cell fate decisions in development, differentiation and disease 🧬📍🔍

submitted 17 days ago • 1 comment

Congratulations to @janayf.bsky.social for winning the 2025 Bruce Cattanach Prize from @gensocuk.bsky.social and for delivering an amazing talk.

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FISH mapping in Xenopus pygmaeus refines understanding of genomic rearrangements and reveals jumping NORs in African clawed frogs www.nature.com/articles/s41...

submitted 19 days ago • 0 comments

Cancer epigenomics at #Epigenetics2025, part 1/2: Carroll: Nuclear receptors in cancer 🧬 Orr: Non-coding variant at 14q24.1 linked to breast cancer 🔍 Azad: Drug-tolerant colon cancer reprogramming 💊 Helin: Histone mods = disease switches 🎛️ @gensocuk.bsky.social

submitted 18 days ago • 0 comments

Cancer epigenomics at #Epigenetics2025 part 2/2 Vallot: Breast cancer in single-cell detail 🧫 Davies: PAX8’s solo act in ovarian cancer ⚔️ Tomkova: Activating genes with methylation ✨ Behrens: Plasticity in pancreatic tumors 🔬 @gensocuk.bsky.social

submitted 18 days ago • 0 comments

Awesome to be able to share our work on PAX8 in high-grade serous ovarian cancer, super job @daviesmolly13.bsky.social! Thanks for the opportunity to share @gensocuk.bsky.social @ucd-sbbs.bsky.social @ucdresearch.bsky.social

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That’s a wrap on the @gensocuk.bsky.social Epigenetics meeting in Belfast, what an absolute treat it’s been! #Epigenetics2025

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I had a lovely meeting on #Epigenetics2025 in Belfast organized by the @gensocuk.bsky.social. Inspiring talks and interactions!

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Great to meet new and familiar faces and share our latest thoughts on strategies to finely tune gene expression at #Epigenetics2025!

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New computer progam by Jinliang Wang to estimate IBD coefficients, inbreeding and relatedness from marker genotypes EMIBD9 Available at www.zsl.org/about-zsl/re..., or at zenodo.org/records/6672... go.nature.com/42YTS1F

submitted 19 days ago • 0 comments

Last talk of #Epigenetics2025 with Axel Behrens discussing cellular heterogeneity and plasticity in pancreatic cancer

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Marketa Tomkova discussing activation of bivalent genes by de novo DNA methylation #Epigenetics2025

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I was incredibly grateful to receive recognition for my work and for the opportunity to present at this very exciting conference! Thank you!

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Last morning of the conference with Molly Davies talking about how PAX8 coordinates oncogenic transcription independently of stable interactors in high-grade serous ovarian cancer #Epigenetics2025

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🧬 Happy DNA Day! Today we celebrate the completion of the Human Genome Project in April 2003 and the discovery of the double helix of DNA in 1953! #DNADay

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Last talk of the day with Emma Farley from @ucsandiego.bsky.social explaining the grammar of developmental enhancers #Epigenetics2025

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Christopher Letai discusses NAD+ maintenance and stress resistance in chronological lifespan extension of Saccharomyces cerevisiae #Epigenetics2025

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Next we heard from @hannahlong.bsky.social on how neanderthal-derived variants within a disease-associated enhancer shape craniofacial activity across recent human evolution #Epigenetics2025

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We started the last session of the day on Epigenetic dysregulation in disease: Complex diseases with @jorge-ferrer.bsky.social talking about defects in cell-specific expression states as culprits of human metabolic disease #Epigenetics2025

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Congrats Janay 👏🏼👏🏼🏆🏆 @gensocuk.bsky.social

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🎉 Congratulations @janayf.bsky.social on winning our 2025 Bruce Cattanach Prize! Janay's talk is on the epigenetic plasticity in response to environmental stress: insights from an evolutionary fish model #Epigenetics2025

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Epigenetic twists in immunity at #Epigenetic2025: Mehdipour: ncRNAs = cancer’s codewriters 🧬 Nally: GSK-J4 does more than demethylate ⚗️ Bauset: Inflammatory memory in histone marks 🔥 Chuong: TEs as stealth regulators in immune response 🧫 #Immunology #CancerBiology @gensocuk.bsky.social

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We are now hearing from @edchuong.bsky.social on Transposable elements as sources of regulatory variation in immunity and cancer #Epigenetics2025

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Cristina Bauset from @ucddublin.bsky.social is now talking about a persistent inflammatory phenotype in TWEAK-primed intestinal fibroblasts which associated with altered histone modification patterns #Epigenetics2025

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Next up is Ken Nally from @ucc.ie discussing how orthogonal validation reveals off-target demethylase-independent anti-inflammatory activity of the UTX/JMJD3 demethylase inhibitor GSK-J4 #Epigenetics2025

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We start our afternoon session on Epigenetic flow of information: Immune cells with @parinazmehdipour.bsky.social decoding non-coding RNAs in cancer, from regulators to therapeutic targets #Epigenetics2025

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Epigenetic flashbacks at #Epigenetics2025: Brickman: TFs remember, enhancers store 🧠 Metzis: A dual-function enhancer sets the Cdx2 timer ⏳ Wang: scMTR-seq = histone + RNA stories in one cell 🧬 Gribnau: Past enhancer activity maps future cell fate 🔍➡️ #Development @gensocuk.bsky.social

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Last talk before the flash poster session by Joost Gribnau on retrospective analysis of enhancer activity and transcriptome history; defining cell signalling pathways directing development and cell differentiation #Epigenetics2025

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We continue the session with @vmetzis.bsky.social from @mrc-lms.bsky.social discussing how a dual enhancer-attenuator element ensures transient Cdx2 expression during development #Epigenetics2025

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We start our next session on Epigenetic flow of information: Stem cells and early development with @josh-brickman.bsky.social discussing how transcription factors hold onto the memories and enhancers hold onto them #Epigenetics2025

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Started strong on day 2 💪🏼 3D genome talks at #Epigenetics2025: Oudelaar: How genome folds regulate genes Sandovici: Promoter contacts in adipogenesis Feldmann: Developmental gene activation via transient interactions Furlong: Enhancer-promoter looping in focus @gensocuk.bsky.social

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Closing the first morning session on Epigenetic Mechanisms: 3D genome organization we heard from @eileen-furlong.bsky.social and Going loopy studying enhancer-promoter communication #Epigenetics2025

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At #Epigenetics2025, Angelika Feldmann from @dkfz.bsky.social presented how transient promoter interactions modulate developmental gene activation!

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Next we heard from Ionel Sandovici on Genome-wide analysis of promoter contacts identifies novel regulators of late-stage adipogenesis #Epigenetics2025

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Powerful talks at #Epigenetics2025 on epigenetic memory: Özdemir: Inheriting H3K27me3 Belton: Non-canonical imprinting insights Cavalli: Polycomb & 3D genome in cancer #Epigenetics #Chromatin #GeneRegulation @gensocuk.bsky.social

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We start our second day of #Epigenetics2025: from mechanisms to disease with a talk by @mariekeoudelaar.bsky.social on the mechanisms that drive 3D genome folding and their function in gene regulation.

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🎉 Huge congratulations to Prof. Kathy Niakan on receiving the 2025 Mary Lyon Medal! @niakanlab.bsky.social's Mary Lyon Medal lecture is on the genetic approaches to study early lineage specification in human embryos. #Epigenetics2025

submitted 20 days ago • 0 comments