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georgwinter.bsky.social
Chemical Biologist with passion for Cancer Research, Targeted Protein Degradation & Transcription.Scientific Founder of Proxygen & Solgate. Pats Fan. Dad. winter-lab.com
11 posts 946 followers 161 following
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Posts 10 Comments 6

Excited about programming biology via induced proximity? Then mark June 2026 in your calendar and consider participating in the GRC Conference on Induced Proximity Modalities and Therapeutics that I am co-organizing with @danetteldaniels.bsky.social tinyurl.com/brtuffam

submitted 27 days ago • 0 comments

this is exciting!

submitted 49 days ago • 0 comments

🎄 xmas preprint 🎄 we are excited to share our cryo-EM structure of UBR4 in complex with KCMF1 and CALM1. the PQC ligase forms a massive ubiquitination arena, primed to amplify ubiquitin chains (E4 activity) and boost degradation of defective proteins. www.biorxiv.org/content/10.1...

submitted 67 days ago • 4 comments

We are very grateful for the ERC Consolidator Grant awarded to my research group! Through our interest in TPD, we have developed expertise in proximity induction which we now leverage to directly rewire transcriptional circuits dysregulated or mutated in cancer. cemm.at/news/n/erc-c...

submitted 85 days ago • 11 comments

SAVE THE DATE 🗓️Ubiquitin & Friends Symposium: 8-9 May 2025 in Vienna! Registration will open🔜 Keep an eye out for the announcement 👀 ✨guest speaker lineup👇🧵 +talks from abstracts! Great chance for #ECRs to meet with peers & experts in a friendly setting! 🔗 www.protein-degradation.org/symposium/

submitted 89 days ago • 1 comment

Let's build a starter pack for childhood cancer research. Please send a message to be added! 🎗️ go.bsky.app/Tpd9QnM

submitted 94 days ago • 28 comments

My "Scientists to Follow" Starter Pack has reached its capacity of 150. Some really exciting additions including @verhelstlab.bsky.social, @supertifurgalab.bsky.social, @georgwinter.bsky.social, @kusterlab.bsky.social, @kimmb1.bsky.social and @katyavinogradova.bsky.social go.bsky.app/3SyoVNw

submitted 90 days ago • 0 comments

Dual-ligase PROTACs: a novel approach for enhancing TPD. By recruiting two distinct E3 ligases within a single molecule, we amplify degradation efficacy & potentially mitigate resistance occurrence. Great collabo with the Ciulli lab & friends at Promega. pubs.acs.org/doi/10.1021/...

submitted 90 days ago • 1 comment

I had the chance to see this amazing story presented recently and I'd strongly recommend to read the Nature paper by our friends in the Obenauf lab @obenaufa.bsky.social Congratulations to all involved!!

submitted 91 days ago • 0 comments

Check out this list of ubiquitin and Ubl profiles to follow. Repost if you want me to add you to it. Let’s create a good community here ☁️ go.bsky.app/3VPQofn

submitted 103 days ago • 6 comments