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gracechoung.bsky.social
Renal pathologist @CedarsSinai #renalpath #transplant opinions are my own
5 posts 71 followers 313 following
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Posts 15 Comments 1

Pauci-immune necrotizing & crescentic GN is usually associated with +ANCA. BUT can also be associated with endocarditis (like this case). Negative ANCA & anti-GBM may be helpful, but up to 33% of endocarditis can have ANCA (esp. Bartonella). #RenalPath #pathsky #nephsky

submitted 5 days ago • 1 comment

Society of Black Pathology is a nonprofit dedicated to addressing barriers to health equity, decreasing health care disparities, and increasing the number of underrepresented individuals in pathology and laboratory medicine. Learn more: buff.ly/4aZsAul #SocBlackPath #BlackHistoryMonth #PathSky

submitted 5 days ago • 0 comments

Occasional thin appearing GBM segments can be seen cases of advanced diabetic glomerulopathy (1-5% of surface areas) with otherwise thickened GBM. Thought to represent new vessel formation; not to be confused for COLIV related disease. #renalpath #nephsky #pathsky pubmed.ncbi.nlm.nih.gov/2456298/

submitted 20 days ago • 0 comments

Doesn't get much worse than this. Severe vascular rejection (transmural inflammation and necrosis - v3) in a transplant bx. Also severe tubulointerstitial inflammation/C4d+, mixed AMR/ACR. #renalpath#nephsky #pathsky

submitted 6 days ago • 0 comments

My daughter who is a 2nd time transplant recipient currently back on dialysis has Medicaid as her backup. If they cut Medicaid, millions like my daughter will be forced to choose what care they have to pass on that keeps them alive because of out of pocket costs.

submitted 8 days ago • 0 comments

Happy Valentine's Day 💘

submitted 16 days ago • 0 comments

Diabetic kidney disease involves all kidney compartments. Examples of severe arteriolar hyalinosis of both afferent and efferent arterioles (characteristic of DN) and very thickened tubular basement membranes. #renalpath #pathsky #nephsky

submitted 24 days ago • 0 comments

Staph epidermidis + urine culture not always contaminant. KTx Bx with rising sCr. Patchy neutrophilic casts and interstitial inflammation suggestion of acute pyelonephritis. #renalpath #nephsky #pathsky

submitted 23 days ago • 0 comments

🔬 Genetic testing is a game-changer in nephrology, but it’s still not routine practice. This paper lays out a clear framework for when and how to use genetic testing in kidney care. 🧵1/4 www.sciencedirect.com/science/arti...

submitted 33 days ago • 1 comment

Younger pt who presented with history of diarrhea and AKI without significant PMHx and no medication use. Bx demonstrated Granulomatous interstitial nephritis. Colon biopsies with chronic active colitis with granulomas c/w with crohn disease --> GIN (no mesalamine) #renalpath #pathsky #nephsky

submitted 36 days ago • 2 comments

Elderly patient with DM ,HTN, CAD p/w SOB, edema, AKI, & oliguria. Low C3. UA 3+ prot,wbcs+rbcs. Urine Cx +ecoli. Acute bacterial infection-related GN-exudative (lots of neutrophils) and starry sky C3 (IF) + hump-like subepithelial deposits (EM) t.co/q3QEy4ZnQP #renalpath #PathSky #NephSky #MedSky

submitted 36 days ago • 1 comment

Lambda-restricted myeloma cast nephropathy *Diffuse ATN *Glassy fractured eosinophilic casts on H&E w cellular reaction *PAS pale *Polychromatic (red and blue) on trichrome #pathsky #nephsky #medsky

submitted 36 days ago • 0 comments

#Quiz from July 2024: A 61-year-old female patient presented with severe bilateral flank pain; her CT scan showed a right perinephric hyperdense lesion. What is the differential diagnosis for spontaneous perinephric hematoma? https://bit.ly/3Cit169 (FREE)

submitted 37 days ago • 0 comments

Example of necrotizing lupus vasculopathy. Hilar arterioles with luminal immune complex deposit and mural necrosis. Ig deposition in lumen of vessel and fibrinogen staining by IF. #renalpath #pathsky #nephsky

submitted 38 days ago • 0 comments

While C3 by pronase IF on FFPE is less sensitive/reliable, it can still be helpful when positive. Left frozen C3, right FFPE C3 from a case of recurrent C3GN in a txp. Did IF par to rule out masked deposits just in case (there were non). So the stain can work. #renalpath #pathsky #nephsky

submitted 37 days ago • 0 comments