groth-anja.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

SAVE THE DATE! The next EMBO | EMBL Symposium on 'DNA replication and genome maintenance: from basic biology to disease' will be held October 20-23, 2026. Organized by Helle Ulrich (IMB), Johannes Walter (Harvard) and Anja Groth (Danish Cancer Institute). www.embl.org/about/info/c...

submitted 13 hours ago • 1 comment

Inexplicably, US administration has launched an unprecedented assault on science, on research institutions & on vital international organizations & initiatives. An assault on science anywhere is an assault on science everywhere; the global community must unite 🧪 www.nature.com/articles/d41...

submitted 1 day ago • 10 comments

Epigenetics Gordon Research Conference. Consider joining us for what will be an excellent, exciting meeting and will be held in Europe for the first time: 10-15 Aug25 Barcelona, Spain. Please repost and apply early - this meeting is popular! www.grc.org/epigenetics-...

submitted 1 day ago • 1 comment

For the US to side with Russia and North Korea to oppose a UN resolution condemning the illegal invasion of Ukraine defies all common sense and adds insult to the countless injuries suffered by the brave Ukrainian people. edition.cnn.com/2025/02/24/p...

submitted 1 day ago • 3758 comments

Excited to share James Jusuf's preprint: By integrating Micro-C with SuperRes Live-Imaging we can calibrate genomics&imaging to perform absolute quantification of looping (e.g. this loop is present 3%) We quantify mESC 36k loops: <loops> are generally rare (2.3%) www.biorxiv.org/content/10.1...

submitted 41 days ago • 6 comments

Proud to share our latest publication in @narjournal.bsky.social! A fantastic team effort led by @marcelwerner.bsky.social and Manuel T., where we explore the chromatin dynamics at transcription-replication conflicts (TRC) sites and their impact on genome stability using a novel TRC reporter system.

submitted 6 days ago • 3 comments

At @science.org today, an important new way we can make major headway into immunologic and infectious diseases. Sequencing the lymphocyte B and T cell receptors and A.I. to accurately make the diagnosis! www.science.org/doi/10.1126/science.adp2407 A seminal study by @anshulkundaje.bsky.social et al

submitted 6 days ago • 4 comments

Happy to share our review on the cellular responses to RNA damage 🥂 Congrats to joined first authors Jacqueline Cordes & @shubozhao.bsky.social www.cell.com/cell/fulltex...

submitted 6 days ago • 0 comments

Finally something/someone worth posting on Bluesky: Europe must stand strong behind Ukraine and Zelensky and resist Trump’s love affair with imperialist dictators and plutocrats (the very rich). It’s our only hope.

submitted 7 days ago • 0 comments

👏👏

submitted 7 days ago • 0 comments

ACTION THIS WEDNESDAY: Researchers from New York universities are holding a rally to protest the funding cuts at Washington Square Park at 4 pm. This will be part of a national day of action, with rallies at HHS in DC and all around the country. RSVP HERE: docs.google.com/forms/d/e/1F...

submitted 9 days ago • 6 comments

Researchers at Fred Hutch have discovered an overlooked mechanism driving aggressive breast and brain tumors involving genes so ancient — more than 2 billion years old — that they fly under the radar of standard genetic sequencing methods. 1/9 www.science.org/doi/10.1126/...

submitted 13 days ago • 1 comment

Happy to share our latest work on phosphoprotein phosphatase (PPP) regulation. We integrate CRISPR knockout and focused base editor screens to uncover the regulatory landscape of PPPs (more below). Great collaboration with the Zhu, Davey, Kettenbach and Ogris labs. www.biorxiv.org/content/10.1...

submitted 10 days ago • 1 comment

Here’s a gift link. This is a good one to share with your non-scientist friends and family www.nytimes.com/2025/02/14/o...

submitted 11 days ago • 0 comments

Come and joint us at @mrclmb.bsky.social ! We have an opening for a new group leader in the Structural Studies Division. We are very interactive and collaborative with amazing facilities and generous core funding. Get in touch with myself or @sjorsscheres.bsky.social if you have any questions.

submitted 19 days ago • 0 comments

FUNDED! I will be recruiting soon a computational #postdoc. If you fancy working on exceptional #singlecell #omics datasets to explore the role of #XChromosomeInactivation in the #sexdifferences of #autoimmune diseases contact me! Predoc fellows with prior experience are also invited to apply!

submitted 13 days ago • 0 comments

Interested in exploring epigenetic cell memory? Join us!! 6 PhD and postdoc positions available in our new center, EpiC.

submitted 14 days ago • 0 comments

Making intrabodies from antibodies just got easier! Learn how we made 𝟭𝟵 intrabodies to bind and light up peptides and histone modifications in live cells. And thanks to Academia, all sequences are freely available. (video credit: Yuko Sato @YukoSatoT2) (1/15) www.biorxiv.org/content/10.1...

submitted 14 days ago • 12 comments

Of course! www.theguardian.com/world/2025/f...

submitted 15 days ago • 1 comment

In honour of #InternationalDayofWomenandGirlsinScience this week, we are revisiting timely #DMMEditorials from fantastic #WomeninScience who are part of our editorial team. First, Monica Justice discusses the importance of including both sexes in research. https://doi.org/10.1242/dmm.050759

submitted 15 days ago • 1 comment

Dear all, Postdoc positions are available to work on (1) the role of DNA strand break repair proteins during DNA replication and (2) the molecular/structural biology of XRCC1 protein complexes, as part of our work on genetic diseases & cancer. Contact me if interested: [email protected]

submitted 16 days ago • 1 comment

Exciting news!🌟 Together with Alexander van Oudenaarden, @jervdberg.bsky.social and @lleonie.bsky.social, we’ve been awarded a €2M NNF Synergy grant. We're thrilled to collaborate🤝 and to develop cutting-edge single-cell and single-molecule methods for replication and chromatin research! 🚀

submitted 68 days ago • 1 comment

Job alert.🚨 Come join us in beautiful Copenhagen 🇩🇰 to develop computational tools to decode gene regulatory mechanisms from single cell data.💻🔬🧫 @randersson.bsky.social will be hiring either a PhD or a PostDoc. There is no supervisor I could recommend more! tinyurl.com/3v4uvmz4 tinyurl.com/yc83enfa

submitted 19 days ago • 1 comment

Hello, Bluesky! ☀️ We fund frontier research in Europe—bold ideas, unexpected discoveries and science that shapes the future. So it’s only fitting we’ve landed here. Sorry for being late. Follow us for updates on ERC funding, research policy, and our grantees' discoveries.

submitted 19 days ago • 43 comments

“...to care is an act not of weakness, but of strength.” The Lancet response: bit.ly/4jRb5Av

submitted 19 days ago • 15 comments

Excited to announce that the EMBO workshop on Enhancer Mechanics and Enhanceropathies, June 16-20, 2025, Hindsgavl Castle, Middelfart, Denmark, is now open for registration and abstract submission. !! SAVE THE DATE and register soon !! 👇 meetings.embo.org/event/25-enh... #EMBO #enhancer

submitted 20 days ago • 1 comment

We are delighted to announce that the website for registering for the 8th EU US Conference on Endogenous DNA Damage and Repair is now open (www.endodnadamage.com)! @orlandoscharer.bsky.social @barbaravlb.bsky.social @emgsus.bsky.social @brownuresearch.bsky.social @weldeiry.bsky.social

submitted 20 days ago • 0 comments

Don’t miss the early bird registration for this exciting meeting focused on neglected areas of genetics, cellular and structural biology. Lots of slots for speakers selected from abstracts. 2-4 April 2025 in Edinburgh.

submitted 20 days ago • 0 comments

Job alert! We are hiring a postdoc or PhD student focusing on * developing computational methods to resolve gene regulation in single cells * investigating the mechanisms and cell-type specific effects of genetic variants PhD student: bsky.app/profile/jobr... Postdoc: bsky.app/profile/jobr...

submitted 20 days ago • 0 comments

Next Wed 12.02. at 6pm CET I will be speaking about our latest preprint: www.biorxiv.org/content/10.1... and present our findings on how we developed a machine learning model that identified new reprogramming barriers, such as H3K27ac, and our in vivo experiments to test it. See you there!

submitted 20 days ago • 0 comments

Exciting work! Congratulations @jansenlab.bsky.social 🙌

submitted 20 days ago • 0 comments

Excited to present Social DNAing tomorrow. I’ll talk about our work led by @szmyd-radoslaw.bsky.social in collaboration with @radoncdocgee.bsky.social. 12 pm Eastern USA Thanks Shan Zha for the invite. www.cancer.columbia.edu/research/pro...

submitted 21 days ago • 0 comments

I've never seen a piece in Science that raidates more emotion- to use the author's excellent phrase, "volcanically pissed off". Essential (if awful) reading. What's Happening Inside the NIH and NSF | Science | AAAS www.science.org/content/blog...

submitted 21 days ago • 1 comment

This is not my normal field but it was written by my husband- he is meant to be promoting it but doesn't do social media so you have to make do with me instead 😄 Cohesin as an essential disruptor of chromosome organization: Molecular Cell www.cell.com/molecular-ce...

submitted 21 days ago • 1 comment

Happy to share this concise review and outlook for single-cell sequencing methods to unravel cell biology of the nucleus! Big shoutout to my friend and former colleague Peter Zeller for sharing the work! www.sciencedirect.com/science/arti...

submitted 22 days ago • 0 comments

⚠️DEADLINE APPROACHING ⚠️ #BGFP25 early bird and talk submission deadline closes on 30 Jan 2025! 🧬 Don't miss out on the opportunity to present at this fantastic conference in beautiful Portugal, submit your abstract now ➡️ bit.ly/3AnsVZF

submitted 29 days ago • 1 comment

Don’t forget to apply! This is an amazing opportunity!

submitted 25 days ago • 1 comment

EMBO Workshop – DNA topology and topoisomerases in genome dynamics. 15-19 September 2025 Szklarska Poręba, Poland REGISTRATION NOW OPEN Interested in attending? Visit the website: meetings.embo.org/event/25-dna... Register by: 15 March 2025

submitted 26 days ago • 0 comments

Now out in @science.org w/ @jshendure.bsky.social we present 'Genome-shuffle-seq': a method to shuffle mammalian genomes and characterize the impact of structural variants (SVs) with single-cell resolution in one experiment. www.science.org/doi/10.1126/...

submitted 26 days ago • 3 comments

Check out our lab’s latest work on the regulation of transcription by RECQL5 helicase! This work was co-led by @alfredo0712.bsky.social and @nlue8.bsky.social, with contributions from Patricia Grob, Ben Kaeser, Jie Fang, and Susanne Kassube. 1/7 www.biorxiv.org/content/10.1...

submitted 27 days ago • 1 comment

Kinases play a role in many diseases, making them prime targets for therapeutic intervention. Enter PhosX, a new tool transforming the way researchers analyse and interpret kinase activity. Read the full article: academic.oup.com/bioinformati... @alussana.bsky.social @epetsalaki.bsky.social

submitted 30 days ago • 1 comment

The fear of failure is holding us back in so many ways. We lose our creativity and we lose our curiosity- although the return of investment could be so big.

submitted 30 days ago • 0 comments

We have 7 projects available for undergrad & master students interested in #AI, #chromatin and #epigenetics. 🧬The Chromatin Dynamics and Epigenetics Lab, led by @robertife.bsky.social, will host an intern during this summer. 🤩Do you want to be her/him? 👉 www.helmholtz-munich.de/en/epigeneti...

submitted 30 days ago • 2 comments

The #FragileNucleosome is honoured to be collaborating with an upcoming in-person conference: 𝐇𝐢𝐝𝐝𝐞𝐧 𝐂𝐞𝐥𝐥, 𝐃𝐚𝐫𝐤 𝐆𝐞𝐧𝐨𝐦𝐞. 𝘊𝘩𝘳𝘪𝘴𝘵𝘪𝘯𝘦 𝘊𝘶𝘤𝘪𝘯𝘰𝘵𝘵𝘢, one of our organizers, will give a special lecture. #hcdg25 Hope to see FN community members! tinyurl.com/37x72s67 @wbickmor.bsky.social @uoe-igc.bsky.social

submitted 32 days ago • 0 comments

That's a beautiful and important paper

submitted 31 days ago • 2 comments

The Multiscale Genome Organisation is now on Bluesky! Our first post is to announce our next webinar. Join us next week on Tuesday, Jan. 28th at 12:00 E.T. for two exciting talks by Pablo Dans and @gfudenberg.bsky.social See you all there! Link: mit.zoom.us/j/91715298970

submitted 37 days ago • 0 comments

Please see 🧵by @evhealy.bsky.social about our new paper exploring the role of PRC1 and PRC2 in non-dividing cells 👇

submitted 43 days ago • 0 comments

1/Delighted to announce the newest paper from our lab, “Homologous recombination promotes non-immunogenic mitotic cell death upon DNA damage”, is out today in @naturecellbiology.bsky.social, www.nature.com/articles/s41....

submitted 44 days ago • 6 comments

#1 Happy to share our last work published in @NatureCellBio about a new cell cycle checkpoint that senses nuclear shape & mechanics to guarantee genome integrity www.nature.com/articles/s41.... Great work from @sol-herve.bsky.social & Andrea Scelfo in close collaboration with @katemiro.bsky.social

submitted 49 days ago • 10 comments