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hannahrabrams.bsky.social
Heme/Onc fellow hoping to reduce costs & improve patient/caregiver experiences in cancer care. Views are my own. 🏳️‍🌈 #MedSky
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Medicare stops access to #Telehealth April 1st for almost all. [Even rural pts must drive to a 🏥 office 1st & THEN get telehealth.] This will lead to: 1️⃣ less access to specialty care 2️⃣ poorer outcomes 3️⃣ higher costs for people with cancer #Telemedicine was a step forward. Let's not fall back.

#HodgkinLymphoma survivors can face difficult tx decisions & financial tradeoffs. We want to better understand how cancer (& cancer-related costs) have affected your life so that we can provide better resources in the future. 🚨Last push for our #lymsm #ayacsm #survonc survey. 🙏 Please SHARE.

#tandem25 #leusm Gang: this study from the @fredhutch.bsky.social looked at 207 adults undergoing allo in CR1/CR2 and who had high quality MPFC MRD positivity pre allo. Majority underwent MAC. Median fup 5yr. Relapse 65% with 3yr OS 34%. No sig diff between MAC and RIC.

Beautiful best oral abstract by Masumi Oshima @fredhutch.bsky.social in a giant ballroom @astct.bsky.social on how post-transplant cytoxan significantly reduces chronic graft vs host disease but increases rates of infection.

Fascinating talk on how to predict & optimize cell/gene therapy capacity/throughput from Julie Porter @danafarber.bsky.social. In addition to all the plenary session payers worried by #celltx #genetx costs-- how do hospitals balance urgency & risk that if they treat they won't get paid? #tandem25

There’s been much discussion about CAR T for severe autoimmune disease, incl. lupus & MS. What can we learn about how that might work from patients who have both cancer & autoimmune disease and get B-/plasma-cell directed CAR T? From Jennifer Huang @fredhutch.bsky.social #Tandem25 #OncSky #RheumSky

Fred Hutch at #Tandem25: Catch presentations from Dr. Jennifer Adair, Elizabeth Krantz and Dr. Jennifer Huang on global access to #genetherapy, #cartcelltherapy and more. Details: bit.ly/4jW3ukj

#tandem25 #bmtsm Abrams: exclusion from HCT/CT most commonly due to lack of insurance, unhoused, medication non-adherence, and substance abuse. Broad variability in abstinence time requirements. Top center-reported barriers to all HCT/CT were lack of caregiver and housing concerns.

#tandem25 #bmtsm Abrams: majority of centers require staying <60min for auto, allo, and CART, but informant minority require <30min.

#tandem25 #bmtsm Abrams: caregiver days required similar overall.

#tandem25 #bmtsm Abrams: survey of NCCN centers re non-medical barriers to alloHCT. N=31/34 centers responded. Differences in caregiver allowances; limited option for prolonged inpatient stay in lieu of optimal caregiver plan.

#tandem25 #bmtsm Giralt: Bortin Lecture: more than 450 attempts before first successful BMT. Giralt’s work on CML alloHCT contributed to it being one of the most common indications historically… until STI-571 (Gleevec), which he joked meant “Stop Transplants Immediately” 😂😂

Come learn along with me from yesterday's #Tandem25 plenary on the economics of novel cell/gene therapies. Informally subtitled, "...How are we going to pay for this?" @astct.bsky.social

Statement at #Tandem25 thanking NIH contributors not able to join the meeting took me aback: #OncSky

a very practical study in Haematologica supporting that the platelet cutoff of 50K for an LP is quite arbitrarty! haematologica.org/article/view...

Cancer survivors are increasingly older & experience high rates of functional impairment, comorbidity, & complications, often necessitating medical equipment. Despite extensive work on #financialtoxicity, the high & often unmet cost of medical equipment remains underrecognized. #survonc

If you have been affected by the fires in LA, or are concerned about your ability to keep precious Drosophila strains going during the latest funding crisis, we will host your strains as a backup. Please email me. Please amplify. If you are also able to host fly strains, add your name as well.

friendly reminder: relatively unimportant choices for clinicians can have major impacts on patients in my ED we have 3 main options with increasing cost, accuracy, time to result and # of bugs tested: -rapid flu + COVID NAAT -4plex (flu A, B, COVID, rsv) -respiratory pathogen panel

🧵 #MedSky #OncSky #IDSky #CardioSky @FTC has released a report finding that pharmacy benefit managers (PBMs) charge markups up to thousands of percent for #cancer, #HIV, & other life-saving generic drugs, netting billions of 💵 in profit while patients pay more. www.ftc.gov/news-events/...

🚨 The #FinancialToxicity special issue of JCO OP is LIVE today! 🚨 We hope these papers will encourage the next gen of researchers to generate, evaluate, & disseminate patient-centered, high-quality, evidence-based medicine & policy solutions to close the affordability gap! ascopubs.org/toc/op/21/1

"Should our patients go to Disney World?" Great editorial & article. In the adult setting, while Disney does sometimes come up, this is often "should I go to Thanksgiving/Christmas?" There are often no right answers & need individualized discussions. #OncSky #CanSky ascopubs.org/doi/10.1200/...

New from @statnews.com Some @fda.gov action on #PulseOx, at long last ... but is it enough? [Spoiler: it's a step, but many more are needed] www.statnews.com/2025/01/06/p...

Another FDA guidance...on accelerated approvals and what "underway" means when the FDA says a confirmatory trial has to be underway to allow an accelerated approval. One wonders about the events that led to a 9 page document explaining the definition of a word! www.fda.gov/regulatory-i...