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hattaca.bsky.social
Assistant Professor at @YaleMed | cell state dynamics, systems biology, computational bio | hormones, ovarian aging, cardiovascular | www.hattiechunglab.bio
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Excited to share this new work led by postdoc Brendan Floyd, deep mapping of cell-surface protein interactomes of T and B cells reveals maverick mitochondrial proteins and immune modulatory complexes. www.biorxiv.org/content/10.1...

submitted 5 days ago • 1 comment

Fantastic Cardiology Grand Rounds on advances in polygenic risk scores from field leader Pradeep Natarajan @pnatarajanmd.bsky.social, introduced by our own Hattie Chung @hattaca.bsky.social

submitted 19 days ago • 0 comments

New: The largest medical A.I. randomized controlled trial yet performed, enrolling >100,000 women undergoing mammography screening The use of AI led to 29% higher detection of cancer, no increase of false positives, and reduced workload compared with radiologists w/o AI thelancet.com/journals/lan...

submitted 20 days ago • 40 comments

Our new paper showing how loss of the nuclear pore protein TPR leads to activation of an inflammatory gene expression programme in senescence is now published in eLife: bit.ly/4h1VcFi @wbickmor.bsky.social @uoe-igc.bsky.social @elife.bsky.social

submitted 47 days ago • 0 comments

Excited to see Moscot (moscot-tools.org) published in @Nature! We scaled Optimal Transport (OT) in single-cell genomics & added multimodality together with spatiotemporal trajectory inference, finding exciting new biology in the pancreas! 🚀 Read at www.nature.com/articles/s41...

submitted 32 days ago • 2 comments

@ImmunityCP preview: Restimulation by macrophages exhausts T cells www.cell.com/immunity/ful... on www.cell.com/immunity/ful...

submitted 40 days ago • 0 comments

Very excited to announce that the single cell/nuc. RNA/ATAC/multi-ome resource from ENCODE4 is now officially public. This includes raw data, processed data, annotations and pseudobulk products. Covers many human & mouse tissues. 1/ www.encodeproject.org/single-cell/...

submitted 47 days ago • 6 comments

Reposting my offer for 1-1 mentoring for anyone… email me and we'll find a time! Especially happy to talk with those from diverse backgrounds and non-traditional career trajectories.

submitted 52 days ago • 1 comment

Our ChromBPNet preprint out! www.biorxiv.org/content/10.1... Huge congrats to Anusri! This was quite a slog (for both of us) but we r very proud of this one! It is a long read but worth it IMHO. Methods r in the supp. materials. Bluetorial coming soon below 1/

submitted 60 days ago • 8 comments

Registration is now open for the 2025 Reproductive Aging Conference! May 4-7, 2025 in San Jose, California This is the only international meeting dedicated solely to mechanisms of reproductive aging. Register today: www.reproductiveagingconference.com @jennifergarrison.bsky.social

submitted 68 days ago • 0 comments

Excited to share our lab's first preprint: we used spatial transcriptomics to dissect how aging disrupts the cycling ovary! 🧵 This was an incredible team effort w/ @jennifergarrison.bsky.social #TammyLan @davidsebfischer.bsky.social #AlisonKochersberger #RuthRaichur #SophiaSzady

submitted 67 days ago • 3 comments

@thejohnnyyu.bsky.social, @therealnima.bsky.social , Kevan Shokat, and I are excited to announce a historic achievement by our team at @vevotherapeutics.bsky.social: tinyurl.com/4rrvap3t

submitted 80 days ago • 4 comments

Incredibly excited to see this brilliant work from @gheimberg.bsky.social #AvivRegev out this week. Years in the making, Graham thought of this before foundation models became cool :) a model for searching & finding the closest cell state, and experimentally validated !

submitted 93 days ago • 0 comments