Profile avatar
hoceklab.bsky.social
Research group at IOCB Prague and Charles University working in bioorganic and medicinal chemistry of nucleic acids and their components. http://hocekgroup.uochb.cas.cz/
7 posts 332 followers 395 following
Getting Started
Posts 8 Comments 2

Ugnė Šinkevičiūtė has successfully defended the Charles University her PhD thesis entitled: New deazapurine nucleobases, nucleosides and nucleotides as potential cytostatics or CD73 inhibitors. PhD No. 47 from the Hocek group. Congratulations !

submitted 15 days ago • 0 comments

Our newest paper on enzymatic synthesis of hypermodified zwitterionic DNA bearing 4 different cationic groups has just been published in NAR. doi.org/10.1093/nar/...

submitted 27 days ago • 0 comments

Filip Gracias has successfully defended at UCT Prague his PhD thesis entitled: Synthesis of epigenetic pyrimidine nucleotides and their non-natural analogues for regulation of transcription. PhD No. 46 from the Hocek group. Congratulations Dr. Gracias! @iocbprague.bsky.social

submitted 37 days ago • 0 comments

Deadline for oral presentation abstracts for the XIXth Symposium on Chemistry of Nucleic Acid Components, Cesky Krumlov, June 8-13,2025 (www.scnac.com) is close (February 20, 2025) - if interested, please apply!

submitted 67 days ago • 0 comments

🧑‍🔬 PhD projects in 2025 See more about the project of @hoceklab.bsky.social at ► www.uochb.cz/en/open-posi... ⤵️ #phd #chemistry #chemie #phdatiocbprague

submitted 79 days ago • 0 comments

Our new paper (collaboration with P. Rezacova group) on the use of environment-sensitive fluorophore-linked nucleotide in DNA probes for identification of effectors of TFs and studying conformational changes of protein-DNA complexes has been published in RSC Chem. Biol.: doi.org/10.1039/D4CB...

submitted 80 days ago • 0 comments

🧑‍🔬 PhD projects in 2025 See the project of @hoceklab.bsky.social at ► uochb.cz/en/open-positions/320 ⤵️ #phd

submitted 82 days ago • 0 comments

#research Enzymatic synthesis of reactive RNA probes containing squaramate-linked cytidine or adenosine for bioconjugations and cross-linking with lysine-containing peptides and proteins (Hocek): nature.com/articles/s42... @iocbprague.bsky.social #charlesuniversity @czechacademy.bsky.social

submitted 89 days ago • 0 comments