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hringbauer.bsky.social
Population Geneticist | Ancient DNA Research Group Leader at MPI-EVA Leipzig www.hringbauer.com
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An important new paper by @beademarch.bsky.social and her team challenges how we use ancient proteins to study the past. Analysis of 1,832 sequences from waterfowl (ducks & geese) reveals why palaeoproteomics isn't the simple solution we hoped for... 👇🧵 1/4 www.researchsquare.com/article/rs-5...

Huge congratulations to the awesome Dr. Yilei Huang on his stellar PhD defense! 🌟👏🎉 Supervising one's first PhD student is truly special, and I got so incredibly lucky to have worked with Yilei (and the entire Archaeogenetics department @MPI-EVA Leipzig).

New paper with Sarthak Mishra! Maybe it will bring you some joy given all this (waves arms around). "Estimating recombination using only the allele frequency spectrum" 1/2 www.biorxiv.org/content/10.1...

Big aDNA study led by the fantastic @iosiflazaridis.bsky.social that helps to resolve the spread of Indo-European languages. 🗣🧬🌍 Includes genomes of 211 Yamnaya (~3000 BCE) from the Steppes between Hungary and central Asia - revealing a dramatic demographic expansion and extreme mobility. #PopGen

Our papers, out today in @nature.com, show how ancient DNA from the Eneolithic and Bronze Age steppe points to a North Pontic origin of the Indo-European language family and a Caucasus-Lower Volga (CLV) origin of Indo-Anatolian (inclusive of the now extinct Anatolian languages). 1/

If you need another break from current news, come with me 7000 years ago to search for the first speakers of Indo-European languages. 🧪 Gift link: nyti.ms/42ILio5

Indo-European languages are spoken by half the people in the world today. The search for their origins has obsessed scholars for centuries. New @nature.com papers by @iosiflazaridis.bsky.social and others use ancient DNA to pinpoint where Indo-European got its start, and how it may have spread.

😂

How we hunt viruses in the museum: scilog.fwf.ac.at/en/magazine/...

My bluesky debut! One week to the submission deadline for SMBE 2025, Beijing 20-24 July smbe2025.scimeeting.cn @anaignatieva.bsky.social and I are organising a symposium on popgen through time: using ARGs, aDNA, or otherwise to understand the evolutionary processes that shape genomes through time.

In new study, we find dramatic differences in specificities of serum neutralizing antibodies in infants w single infection by a recent SARS-CoV-2 strain versus adults/children imprinted by an early viral strain. www.biorxiv.org/content/10.1...

"the science of extreme longevity continues as an immense joke." www.nytimes.com/2025/01/20/o...

Check out our new research in NPJ Biofilms and Microbiomes on the surprising patterns of oral streptococci variation in humans and the clues they encode for understanding human evolution and the recent impacts of oral hygiene. A big congratulations to Irina Velsko! www.nature.com/articles/s41...

It’s been four hours since the TikTok ban, and I have already written and published my first Linux book, and learned Chinese. I am now going out for a midnight run, and then I will make a protein shake.

Check out our Ancient Genomics Lab, including @pontus-skoglund.bsky.social, @boothicus.bsky.social and Frankie Tait, on tonight’s new episode of Digging for Britain. 🦴 Watch it now on iPlayer (from 46:00), or tune in to BBC Two at 20:00. www.bbc.co.uk/iplayer/epis...

Y'all, there is now a Paperpile extension for Word. This should be useful for a lot of us who have heavy Word users and heavy Google Doc users on the same writing teams. paperpile.com/word-plugin/

Last days to apply for this PhD position in Computational Population Genetics @MPI_EVA_Leipzig (the deadline is January 15th)!

Thrilled to have been a part of this study led by @aidaandres.bsky.social that finds evidence of genetic adaptation in chimpanzees to different habitats. Most notably signatures of positive selection in chimpanzees underlie resistance to malaria in humans (GYPA and HBB).

"Ancient DNA reveals family ties" is named on of the top 10 Science Break-throughs in 2024 by Science (www.science.org/doi/10.1126/...). Our work on early Celtic princely burials and their discovered close kinship gets mentioned, too! #ancientDNA #science

Cool work led by Leo Speidel and @pontus-skoglund.bsky.social - combining ARG inference on high quality aDNA with the qpAdm admixture framework! 👏💻🧬

It is out! A story about how sedaDNA can help to reveal undocumented fauna presence and be used together with zooarcheology in the Pleistocene context! The preservation of sedaDNA in El Miron Cave is exceptional 😍🪨🐅 @heasvienna.bsky.social www.nature.com/articles/s41...

🏺 Exaltations to my colleague Leo Speidel! He developed a method for looking at ancient human ancestry in finer detail, allowing us to better distinguish between very similar ancestries, for instance ancestries carried by populations of N. Europe in 1st Mill CE. www.nature.com/articles/s41...

In Top10 @ScienceMagazine 2024 breakthroughs of the year: Reconstructing ancient pedigrees + IBD segment sharing in aDNA. 😮😊 🎉 Great write-up by @spoke32.bsky.social ! 👏👏

Fascinating how IBD segment sharing in aDNA connects a time series of very diverse people in Migration period Hungary. Shifting IBD networks reveal the specific impact of the Hungarian conquerors from the Ural compared to earlier Avars. Great work by Gerber et al.! 👏👏

Related to the last post, bold stuff on syphilis origins in the Americas. www.nature.com/articles/s41...

👏👏 @arevsumer.bsky.social ! Contains our IBD analysis led by Yilei Huang: Multiple really long 20cm++ IBD segments link the two record 45ky-old sequenced modern human sites Zlatý kůň (Czechia) and Ranis (Germany). Showing they are closely related - within few generations! 😮😮 (1/3) #PopGen #aDNA

Out today in @sciencemagazine, we've journeyed into our shared history with Neandertals by analyzing over 300 present-day and ancient modern humans, including 59 individuals who lived between 2,000 and 45,000 years ago. www.science.org/doi/10.1126/...

Very excited to see our study published today, joint effort with @benmpeter.bsky.social group, co-led by @leonardoiasi.bsky.social & Manjusha Chintalapati. Excitedly, @arevsumer.bsky.social et al. in Nature today show similar timeline of N gene flow. Details👇

Today is a very big day for our research group, with two of my students, @leonardoiasi.bsky.social and @arevsumer.bsky.social publishing papers on the same day! www.science.org/doi/10.1126/... www.nature.com/articles/s41... #Neanderthals #gene-flow

True! ⬇️

Nice - MCEB 2025 will be in Granada 🇪🇸☀️. They keep having those amazing locations! It's always a fun computational genomics conference with a great audience.

For its 2025 instalment, the conference "Mathematical and Computational Evolutionary Biology" (MCEB) will take place in Granada, Spain ! It will focus on methods and models for phylogenomics and population genomics, with a great lineup of keynote speakers. mceb2025.sciencesconf.org?lang=en

PhD opportunity in computational population genetics at @MPI_EVA_Leipzig: Join our fully funded project to develop IBD-segment tools, connecting high-quality genomes from 500 Black Death victims to modern Europeans. 🌍💻🧬 Please spread the word! 📢🙌 #aDNA #PopGen www.eva.mpg.de/de/karriere/...

"Short sleep" candidate genes are a classic example of zombie bad science which refuses to die. Announced with great acclaim 2009-2021 but decisively debunked in a 2022 biobank study (linked). Debunking has just 7 citations while originals still get 100s a year and keep going viral in popsci land.

Don't forget to submit your abstract for "Probabilistic Modeling in Genomics 2025". Deadline: January 10th, 2025. meetings.cshl.edu/meetings.asp...

⬇️ Useful collection by @shaicarmi.bsky.social: There is now a whole zoo of methods to transfer polygenic scores across populations. 🔥 topic.