hubrechtinstitute.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

What do long-range enhancers need to regulate genes? Researchers from the De Laat group have found that long-range enhancers require optimal regulatory protein levels, in addition to the specific protein complex cohesin, to switch on genes. Read more here: www.hubrecht.eu/long-range-e...

submitted 1 day ago • 0 comments

The organoid group has discovered that specific gut epithelial cells, known as BEST4/CA7+ cells, maintain fluid homeostasis and expand significantly to combat bacteria that cause diarrhea. They are the primary targets of bacterial diarrheal toxins. Read more 👉 www.hubrecht.eu/new-insights...

submitted 1 day ago • 0 comments

How do cells find their place in a developing embryo? Scientists have long wondered. A new study by the Hiiragi group uncovers how embryos achieve precise cell organization. Curious what breadcrumbs have to do with this? @prachitimoghe.bsky.social explains it here: www.hubrecht.eu/breadcrumb-t...

submitted 8 days ago • 0 comments

How do cells measure time? Despite its fundamental role in development, the underlying mechanisms remain unclear. An NWO ENW-XL grant allows a research consortium from the Hubrecht Institute, AMOLF, TU Delft, and ENS Paris to study timing regulation in C. elegans. www.hubrecht.eu/how-do-cells...

submitted 12 days ago • 0 comments

On this International Day of Women and Girls in Science, we aim to empower women and highlight the vital role of diversity in science. Stieneke, with 45 years of experience, and Anastasia, a first year PhD-student, sat down together to discuss this topic. Watch it here youtu.be/xtHAM-mTddQ

submitted 15 days ago • 0 comments

The Hubrecht Symposium is coming up soon! Registration is open until February 20th, submit your abstracts for talks and posters by February 13th. Join this inspiring day on the topic of developmental biology - morphogenesis and cell fate decisions! hubrecht.eu/hubrecht-symposium-2025/registration/

submitted 19 days ago • 0 comments

Catherine Robin has received a philanthropic donation facilitated by the Foundation Friends of the Hubrecht Institute. Robin’s group will develop bioprinted aortas to produce transplantable blood stem cells to make future stem cell transplants more accessible. www.hubrecht.eu/catherine-ro...

submitted 21 days ago • 1 comment

Seeing ribosomes in action? Thanks to researchers from the @marvintanenbaum.bsky.social lab this is now possible. They created a technology to track individual ribosomes during mRNA translation. The team found that ribosomes ‘help’ each other in difficult situations www.hubrecht.eu/ribosomes-te...

submitted 26 days ago • 0 comments

"There is a lot of uncertainty and fear there currently", says our director Geert Kops on NPO Radio 1 about Trump's NIH restrictions. With Eddie Brummelman, he discusses the impact on biomedical research in the US and Europe. Watch the interview back 👇(Dutch) www.nporadio1.nl/nieuws/binne...

submitted 28 days ago • 0 comments

What if science truly is like volleyball, where teamwork and support are everything? We spoke with @fmattiroli.bsky.social, who recently earned tenure, to explore this question and more. Read her inspiring story here 👇 www.hubrecht.eu/francesca-ma...

submitted 37 days ago • 0 comments

On Jan 9, now dr. Henriette van Beijnum defended her PhD on the regenerative abilities of the spiny mouse. Congratulations! Her findings, like the flexible “basket-weave” scar pattern, could help improve treatments for heart attacks and chronic wounds. See hubrecht.eu/phd-defense-...

submitted 48 days ago • 0 comments

🫀 Zebrafish protein unlocks dormant genes for mammalian heart repair. Our work published by @springer1842.bsky.social in Nature CVR uncovers how the protein HMGA1 could unlock mammalian heart repair. rdcu.be/d5owa #HeartHealth #Regeneration #Biomedicine #Cardiology

submitted 54 days ago • 2 comments

Researchers from @bakkerslab.bsky.social have successfully repaired damaged mouse hearts using a protein from zebrafish. This study marks a promising step toward regenerative therapies to prevent heart failure. Curious? www.hubrecht.eu/zebrafish-pr... @marabouwman.bsky.social l

submitted 55 days ago • 0 comments

Researchers from the organoid lab developed a method to grow organoids using a bacterial protein: Invasin. The study, published today in @pnas.org, shows that Invasin offers a sustainable, affordable and animal-free alternative to current methods. www.hubrecht.eu/Invasin-prot...

submitted 58 days ago • 0 comments

How reliably is the epigenome passed from one cell to its daughter cells? Alexander van Oudenaarden @jervdberg.bsky.social @grothlab.bsky.social @lleonie.bsky.social received @novo-nordisk.bsky.social grant to study this question ➡️new strategies to prevent disease & combat aging tinyurl.com/yh925b9u

submitted 68 days ago • 0 comments

Jop Kind has been awarded a grant from KWF to further develop a highly sensitive method for detecting cancer using epigenetic signatures in blood plasma. This innovative approach has the potential to revolutionize early cancer diagnosis and monitoring. Read more at www.hubrecht.eu/jop-kind-rec...

submitted 72 days ago • 0 comments

The inaugural Hubrecht Symposium is on March 13th, 2025! Join an inspiring day on molecular & developmental biology. This annual event highlights the role of fundamental research in Dutch science. Free of charge! Submit abstracts by February 13th. See www.hubrecht.eu/hubrecht-sym...

submitted 78 days ago • 0 comments

Congratulations to dr. Yasmine El Azhar, who successfully defended her thesis: Notch signalling dynamics during mouse development and homeostasis. She developed a mouse model to visualize real-time Hes1 oscillations in single cells @sonnenlab.bsky.social. www.hubrecht.eu/phd-defense-...

submitted 85 days ago • 0 comments

Researchers from the organoid group created a new organoid that mimics the human fetal pancreas. Unlike previous ones, this organoid has all three key cell types. They also identified a stem cell that develops into these cells. Curious?👉 www.hubrecht.eu/researchers-... @amandaanderssonr.bsky.social

submitted 86 days ago • 0 comments

🧬New publication out in Nature Communications today reveals how cells fix damaged DNA. Researchers from the Kind group mapped repair proteins and show how they form 'hubs,' to coordinate repairs, almost like a 'repair café'. Read more: hubrecht.eu/dna-repair-p... #DNARepair #SingleCell #Epigenetics

submitted 97 days ago • 1 comment

Dutch Research Council (NWO) Vidi grant for @fmattiroli.bsky.social. With this funding, she and her team will investigate how DNA and its packaging are copied during cell division. Their findings could in the future help to fight diseases and aging. Read more: www.hubrecht.eu/francesca-ma...

submitted 124 days ago • 0 comments

New scEdU-seq method developed by the Van Oudenaarden group measures DNA replication speed in individual cells & may provide new insights into DNA replication, embryonic development and cancer. Read more! www.hubrecht.eu/method-dna-r...

submitted 254 days ago • 0 comments

Congratulations to Delilah Hendriks, for receiving a grant from the Dutch Cancer Society (KWF)! Together with researchers from the Máxima Center, UMC Utrecht, and Avans, she will study how fatty liver disease can lead to liver cancer. Read more about their research: www.hubrecht.eu/kwf-grant-fa...

submitted 309 days ago • 0 comments

Laura Rodriguez Munoz and Gawoon Shim, two researchers from the Hiiragi group, recently received a MSCA Postdoctoral Fellowship. Additionally, Rodriguez Munoz has received an EMBO Fellowship. Read more about their research on early embryonic development: www.hubrecht.eu/msca-embo-fe...

submitted 316 days ago • 0 comments

Congratulations Anne de Leeuw! On March 28th she successfully defended her PhD thesis ‘Decoding Heavy Hearts: Molecular Insights into Hypertrophic Cardiomyopathy’. Read more here: www.hubrecht.eu/thesis-defen...

submitted 329 days ago • 0 comments

Congratulations to Catherine Robin & Riccardo Levato for receiving a ZonMw grant! This grant allows the Hubrecht Institute and Regenerative Medicine Center to join forces and implement an innovative 3D bioprinting technology to study blood stem cell production. www.hubrecht.eu/zonmw-robin-...

submitted 329 days ago • 0 comments

Congratulations to the Lifelong VISION consortium for receiving a Gravitation grant! In this partnership, scientists will join forces to find new solutions for blindness. The group of Jeroen Bakkers contributes by studying retinal regeneration in zebrafish: hubrecht.eu/gravitation-...

submitted 335 days ago • 0 comments