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jamesnolan.bsky.social
Lymphoma+Cellular Therapies fellow at Princess Margaret Cancer Centre Toronto ๐Ÿ‡จ๐Ÿ‡ฆ/ Physician Scientist in Lymphoma/Chromatin Biology ๐Ÿ‡ฎ๐Ÿ‡ช
3 posts 357 followers 295 following
Getting Started

๐Ÿงต 1/ Weโ€™re excited to share that our new paper with @adrianbracken.bsky.social lab is out ๐ŸŽ‰ In this study (which began over 10 years ago!), we explore the biology of PRC2 and PRC1 in non-dividing cells. We also explore the effects of PRC2 inhibitor drugs on these cells. Hereโ€™s what we found๐Ÿ‘‡

Congrats to @jamesnolan.bsky.social (now at @pmresearch-uhn.bsky.social) on his #ASH24 abstract achievement award for his PhD research @tcddublin.bsky.social! @adrianbracken.bsky.social ๐Ÿ‡ฎ๐Ÿ‡ช๐Ÿ‡จ๐Ÿ‡ฆ @ash-hematology.bsky.social #Lmsm #ASHKudos

Looking forward to sharing collaborative work by myself and @dr-chromatin.bsky.social from the labs of @adrianbracken.bsky.social and @conwayer1.bsky.social at #ASH24 in San Diego this week. #hemesky #lymsm please feel free to stop by and share your thoughts.

๐ŸŽ‰๐Ÿ“ข Delighted to share our work from Princess Margaret Cancer Centre ๐Ÿ™Œ๐Ÿผ PTCy-based GvHD prophylaxis was associated with an improved GRFS, NRM, and OS ๐Ÿ’ช๐Ÿผ A big shout-out to @haemophage.bsky.social for his mentorship ๐Ÿ™Œ๐Ÿผ doi.org/10.1182/bloo... #MedSky #HemeSky

How does PRC1 counteract transcription? See this preview from @adrianbracken.bsky.social and I on an exciting new study from @robklose.bsky.social lab where they show ncPRC1 blocks the early stages of transcription. www.sciencedirect.com/science/arti... @conwayer1.bsky.social for title inspo!

My colleague @fergutierrezro1 giving an excellent talk at #ESHBMFS2024 on the clinical implications of clonal hematopoiesis in #telomere biology disorders ๐Ÿงฌ; dependent on specific mutation with U2AF1, TP53, and chr1+ associated with #MDSsm and #AMLsm.