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jaredwhitlock.bsky.social
features editor @endpts.com / fall 2021 fellow @ksjatmit.bsky.social writing (and editing) stories on rare disease medicine, diagnostics and cool tech
40 posts 921 followers 164 following
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Good piece from @andrewedunn.bsky.social on pharmaceutical CEOs "biting their tongues on defending some basic scientific principles, like vaccine safety, and institutions, like the NIH." endpts.com/post-hoc-pha...

Don't miss this deep dive on CRISPR's tremendous promise running up against disenchanted investors. It's a must-read. By @scienceboss.bsky.social endpts.com/biotech-is-s...

NEW: The Trump administration is exploiting a loophole to keep funding frozen at the NIH - a move that some legal scholars say is illegal. Federal Register notices are blocked, so no grant-review sessions can be scheduled. All the gritty details here, and a short 🧵: www.nature.com/articles/d41...

Drug giant Roche has long had a bad reputation in DNA sequencing. But no longer, it appears. Latest here: endpts.com/roche-no-lon...

Journo request: Our features editor @jaredwhitlock.bsky.social is after tips and stories:

Exclusive from @jaredwhitlock.bsky.social: Former FDA chief Robert Califf calls layoffs "haphazard, poorly thought-out." endpts.com/former-fda-c...

Robert Califf, the former head of the FDA, didn't mince words when I asked him about recent agency layoffs. endpts.com/former-fda-c...

I am the features editor at Endpoints News. We're closely reporting on the Trump administration slashing the federal workforce and the impact on biomedical research. I want to hear your stories and tips. Signal at: @jaredwhitlock.73. I can honor requests for anonymity.

Well, as I said a couple of weeks ago, thank God I'm not a CEO and I don't have to do this sort of dirty work. Because let's not kid around: if it has to do with the intersection of business and the Trump administration as it's been running so far, it's going to end up being dirty.

ARPA-H chief is out as Trump administration cuts health agencies endpts.com/arpa-h-chief...

Exclusive: Drugmakers plan Trump meeting next week amid Washington health shakeups, via @drewsnews.bsky.social endpts.com/drugmakers-p...

Looking to add science journalism to your feed? For over 40 years we've brought journalists to MIT to hone their craft. Now they're on Bluesky ⬇️ bsky.app/starter-pack...

Thomson Reuters has won the first major AI copyright case in the US. The decision has big implications for the battle between generative AI companies and rightsholders.

NIH plans to slash support for indirect research costs, sending shockwaves through science Capping these payments would ‘just grind our scientific complex to a halt,’ one researcher said www.statnews.com/2025/02/07/n...

New study will try to stop Alzheimer’s decades before it begins, using experimental Eli Lilly drug Good piece from Ryan Cross here at @endpts.com endpts.com/study-will-t...

For the first time ever, researchers will use an experimental drug to try and prevent Alzheimer's disease even before the first biological damage has been done. Ryan Cross has the inside story: endpts.com/study-will-t...

After the US targeted Chinese rivals to Illumina, it's no surprise that the company was included in tariff retaliations. More here on today's news and context on the geopolitical dynamic: endpts.com/illumina-add...

"Dark proteins." Also known as microproteins. There are thousands of them in our cells and we're still struggling to define their function. Succinctly reviewed @nature.com www.nature.com/articles/d41...

Private emails show RFK Jr. making false claims about Covid-19 shots, linking vaccines to autism www.statnews.com/2025/01/28/k...

Spatial multi-omics has just gone to the next level! www.nature.com/articles/s41... www.nature.com/articles/s41... —Integration of 5 omic modalities w/ spatial resolution at 20 -50 μm —"a new era for characterizing tissue & cellular heterogeneity that single-modality studies alone could not reveal"

ICYMI my latest in-depth piece: China's biotech boom is threatening US drugmakers' dominance I am continuing to closely report at the intersection of US and China. Feel free to get in touch with tips and ideas. endpts.com/chinas-drug-...

A little-known Chinese biotech startup has zipped ahead of US companies in one of the gene editing field’s most competitive races. endpts.com/chinese-star...

"The billionaire biotech firebrand, who has been Regeneron’s chief scientific officer since its founding 37 years ago, sees both AI and stem cells as examples of powerful tools that also suffer from over-the-top promises." Via @andrewedunn.bsky.social endpts.com/regeneron-cs...

Chinese drug developers are pursuing novel drug targets and hot therapeutic areas like obesity. The exploding trend has sent shocks through the biotech industry and its center of gravity, which has long been anchored in a handful of cities in the US. endpts.com/chinas-drug-...

My latest is an in-depth look at China's scientific rise unnerving the US biotech industry. A 🧵: endpts.com/chinas-drug-...

Great story by @wsjwernau.bsky.social about one effective way to help treat the mental health crisis. www.wsj.com/health/schiz...

My latest Post-Hoc provides some thoughts on the war for AI talent — in short why Big Pharma is losing that battle From reporting on the ground at NeurIPS to close out 2024: endpts.com/pharma-is-lo...

A baby boy born with a debilitating genetic disease will likely no longer require a liver transplant to stabilize his condition, thanks to an experimental treatment.

Balanced piece by David Wallace-Wells in NYT on the discovery of Ozempic, etc., based on Jeff Flier’s oral history from over the summer. (And as a bonus, it cites @ruxandrabio.bsky.social & Willy Chertman’s great new piece on “clinical trial abundance” too!). www.nytimes.com/2024/12/25/o...

Step one: get Timothée Chalamet on here.

The deal ends a months-long competition between two suitors that bid up the price of DNA sequencing company Singular. endpts.com/deerfield-to...

More details emerging about a new company founded by gene therapy pioneer Jim Wilson endpts.com/jim-wilsons-...

Really leaning into getting older. In the last hour I've complained that movie theaters are too loud now, read a physical newspaper and wondered why my knee hurts.

In 2024, I continued to report on rare disease medicine. Some highlights: For 3.5 years, I followed a teenager and his family while a custom treatment was developed for his seizures. The journey revealed a lot about personalized medicine's failures, and promise. endpts.com/a-teenager-f...

Also cut from the congressional bill is the reauthorization of the rare pediatric disease priority review voucher program which helps fund clinical trials & drug development at small companies working on rare diseases. And prescription drug insurance/PBM reform was cut as discussed yesterday #biosky

In this @endpts.com post-hoc analysis, I reflected on a year of reporting on the Biosecure Act. Even if the bill and its next incarnation fails, drugmakers are still weighing how closely to work with Chinese contractors. endpts.com/biosecure-ac...

Lots of good people and accounts in this starter pack for people in the biotech space

It's been really cool to see the accelerating migration to Bluesky. Check out our @endpts.com starter pack for editors / writers to follow. bsky.app/starter-pack...

An international panel says clinical microbiomes aren't ready for primetime...yet 🧬 🦠

This is a wild finding. Apparently the time of day a therapy is given to treat glioblastoma (brain tumour) can affect how well it works. neurosciencenews.com/glioblastoma...

Over 30 prominent scientists call for a ban on the creation of a "mirror cell"--a microbe made of molecules that are mirror images of their natural forms. It could cause a mind-boggling global disaster. Here's my story [gift link] 🧪https://nyti.ms/3OUCXp6