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jeroen.vangoey.be
Staff Research Engineer in BioAI at InstaDeep (part of @biontech.bsky.social)- machine learning for personalized cancer vaccines, de novo peptide sequencing and signal peptides. From Belgium 🇧🇪 currently living in Cape Town 🇿🇦 #bioML #TeamMassSpec
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Inexplicably, US administration has launched an unprecedented assault on science, on research institutions & on vital international organizations & initiatives. An assault on science anywhere is an assault on science everywhere; the global community must unite 🧪 www.nature.com/articles/d41...

Introducing π-PrimeNovo, a non-autoregressive model revolutionizing de novo peptide sequencing! Faster, more accurate with deep learning, it outperforms autoregressive methods! 🚀🔬 #Proteomics PMID:39747823, Nat Commun 2025, @NatureComms https://doi.org/10.1038/s41467-024-55021-3

A transformer-based semi-autoregressive framework for high-speed and accurate de novo peptide sequencing www.nature.com/artic... --- #proteomics #prot-paper

🔬 Interesting read: MARLOWE enables taxonomic characterization of unknown samples using de novo peptide sequencing & „strong“ peptides! Applied to forensic proteomics, it identifies contributors with high accuracy. New Paper out in JPR: doi.org/10.1021/acs.... #Proteomics #Forensics

A long post about what’s happening to the science funding agencies in the US and why. As mentioned, this one just kept getting longer even as I kept stripping curse words from it. www.science.org/content/blog...

Can AI really help with literature reviews? 🧐 Meet Ai2 ScholarQA, an experimental solution that allows you to ask questions that require multiple scientific papers to answer. It gives more in-depth and contextual answers with table comparisons and expandable sections 💡 Try it now: scholarqa.allen.ai

🧪AI-designed proteins can neutralize deadly snake venoms, offering hope for modern, low-cost snakebite therapies. These proteins may overcome the limits of century-old antivenoms, saving lives globally. 🩺 🧬💻

🎉Looking for an exciting opportunity in proteomics and data science?🎉 Join DTU Bioengineering as a #Data #Science Specialist in #Proteomics! Based at our state-of-the-art DTU Proteomics Core. You'll also collaborate with me and the DTU Bioengineering Data Science Hub. lnkd.in/d2zHaMys

Applications are open for the GeoAI Hackathon at #AIActionSummit 2025! 🗓️ 5-6 Feb 2025 Tackle global challenges with AI-powered geospatial solutions! 🌍✨ 👩‍💻Open to Python & ML enthusiasts 🌟The winners will be presented during the AI Action Summit in #Paris! 👉Apply by 26 Jan 2025: geoaihack.com

π-PrimeNovo: an accurate and efficient non-autoregressive deep learning model for de novo peptide sequencing www.nature.com/artic... --- #proteomics #prot-paper

New paper led by Ismael Rodriguez, with @yc386.bsky.social, @rbharathkumar91.bsky.social, @mirandaevans.bsky.social, @jaadekker.bsky.social, @jespervolsen.bsky.social on benchmarking a single degraded protein out in @PCI Mathematical & Computational Biology doi.org/10.24072/pcj... #teammasspec

2024 saw another record for bioRxiv postings. Thanks to all the CSHL staff, affiliates, authors, funders, and everyone who advocates for the project. Happy New Year and #letsmakethisthenorm ! 🧪

NovoRank: Refinement for De Novo Peptide Sequencing Based on Spectral Clustering and Deep Learning pubs.acs.org/doi/10.... --- #proteomics #prot-paper

NovoRank: Refinement for De Novo Peptide Sequencing Based on Spectral Clustering and Deep Learning #JProteomeRes #MassSpec pubs.acs.org/doi/10.1021/...

Really glad we got this opinion piece by Kelly Chibale in @cenmag.bsky.social #chemsky #biotech

Last week, David Baker, alongside John Jumper and Demis Hassabis, received the #Nobel Prize in #Chemistry🏆. It was incredibly special to see our group's and collaborators' work highlighted in the Nobel speech, along with the vital issue of #snakebite #envenoming🎉.

Three BioML starter packs now! Pack 1: go.bsky.app/2VWBcCd Pack 2: go.bsky.app/Bw84Hmc Pack 3: go.bsky.app/NAKYUok DM if you want to be included (or nominate people who should be!)

In one year, I genetically engineered the boring Arabidopsis into a beautiful ornamental flower 🧬🌹 Here is how and why I gave this model organism a visual upgrade 🧵(1/7)

A really nice paper, talking about Open Source and what it means for #Proteomics , one for #teamMassSpec and #chemsky to check out. chemrxiv.org/engage/chemr...

For years, Hunt lab members were tasked with de novo sequencing a notebook full of MS/MS spectra upon joining (still have mine!). This provided a firm foundation for many careers in MS-based proteomics. Thanks to L.Anderson et al for making the “blue book” available to #teammassspec in honor of DFH:

🧪🧬🖥️ Nucleotide Transformer is now published in Nature Methods! A foundational models for genomics, with up to 2.5 billion parameters, that are trained on genomes from 800+ species and 3000+ human individuals. 📄 www.nature.com/articles/s41... 💻 github.com/instadeepai/... #Genomics #BioML #MLSky

An advertorial from Bruker Daltonics about using the de novo peptide sequencing algorithm Novor 2.0 for immunopeptidomics. www.labcompare.com/10-Featured-...

Reposting two starter packs with researchers working on AI4Science for those who are newly joining 🦋. So many wonderful folks on these lists, help me add more by sending names (including your own 😊). Starter Pack 2: go.bsky.app/GnFTUM6 Starter Pack 1: go.bsky.app/JeFdryY

Friends, it's fun to see the #immunology community continue to grow! I created a 4th Starter Pack to help folks find each other. If you're an immunologist and you don't see yourself on the lists, let me know 🧪 go.bsky.app/PY5tCas go.bsky.app/FmERUoD go.bsky.app/6aT6qDS go.bsky.app/QSEPDoj

Protein Sequence Modelling with Bayesian Flow Networks ProtBFN, a 650M parameter Bayesian Flow Network (BFN), generates diverse, structurally sound proteins, outperforming autoregressive and diffusion models. It excels in both unconditional and conditional generation.

Deep Learning Methods for De Novo Peptide Sequencing #MassSpectromRev analyticalsciencejournals.onlinelibrary.wiley.com/doi/full/10....

Recently stumbled upon these talks from the 2024 Genome Sciences Symposium at the University of Washington. #bioinformatics youtube.com/playlist?lis...

Here's another youtube channel with a bunch of talks on the intersection of deep learning/ml and bio www.youtube.com/@valence_lab.... #bioinformatics

New blogpost: The ABCs of Alphafold 3, Boltz and Chai-1 blog.booleanbiotech.com/alphafold3-b...

Congratulations @isma-rgz.mastodon.social.ap.brid.gy et al. on the recent publication in @peercommunityin.bsky.social: Benchmarking the identification of a single degraded protein to explore optimal search strategies for ancient proteins! If you missed the corresponding talk: youtu.be/YJ9OKRR0Tj8

Let's get connected on 🦋. With this starter pack we want to highlight immunology research done by Belgians and/or in #Belgium. go.bsky.app/PZ9BgQM #Immunosky Help us to expand this list.

My first Skeetorial! 💻🧬TCR-TRANSLATE - A new framework for thinking about the TCR:pMHC specificity problem. TLDR: We pretrained LLMs on ~8M TCR & pMHC seqs Finetuned on sparse pMHC->TCR pair data Validated CDR3b sequences to unseen antigens >> random performance on IMMREP2023 "private" antigens

Any chance of getting Biology+AI Daily in here? Biggest X pull factor left for me tbh

I work for company number 9 on this list, InstaDeep, and can confirm that we are using AlphaFold internally. We're actively hiring in London, Paris and Kigali: www.instadeep.com/careers (filter on BioAI department)

Chiang and Collins making a fun Casanovo + Sage (w/Mokapot et al.) metaproteomics pipeline (Bittremieux, @michaellazear.bsky.social @willfondrie.com) … and an exceptional TOC graphic.

RankNovo: A Universal Reranking Approach for Robust De Novo Peptide Sequencing openreview.net/forum?id=87B...