joachimgoedhart.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

Budget released today: 40% cut to NIH 50% cut to NSF If enacted, this will destroy academic research in the United States. It will also have a major trickle down effect on the entire academic ecosystem

submitted 14 hours ago • 18 comments

A non-toxic, user-friendly buffer that enhances green fluorophore performance in conventional and super-resolution imaging by Wim Vandenberg and team: www.biorxiv.org/content/10.1...

submitted 18 hours ago • 0 comments

First time running flow cytometry, and not sure how to pick your markers? Check out the "Designing Your First Flow Panel" blog post, by Paul Heisig! blog.addgene.org/ant...

submitted 19 hours ago • 0 comments

I had some absolutely incredible papers come online this week, and I need to take a minute to post about each of them. First, let me tell you about the CarboTag probes for imaging plant cell walls! From the Sprakel lab (a short thread) www.nature.com/articles/s41...

submitted 1 day ago • 3 comments

I'm fond of sharing and discovering preprints on this platform. Here's how I made a small extension (Firefox only) that simplifies posting preprints from @biorxivpreprint.bsky.social and @medrxivpreprint.bsky.social : thenode.biologists.com/painless-pre...

submitted 1 day ago • 1 comment

🧪Sharing your articles from our journals @dev-journal.bsky.social @jcellsci.bsky.social @jexpbiol.bsky.social @dmmjournal.bsky.social and @biologyopen.bsky.social on Bluesky is now just one click away.

submitted 1 day ago • 1 comment

Come with me as I try to build a modular open-source 24-well Plate Reader from scratch. I'll post updates regularly on this thread and then compile it to my open lab notebook later. Let's make some tools! 🛠️🧵 1/n

submitted 2 days ago • 7 comments

@joachimgoedhart.bsky.social wanted a web extension to easily share #preprints on Bluesky. When he couldn't find one, he decided to create one himself. Find out how he managed to do that in this post👇

submitted 2 days ago • 0 comments

Here's the background story on how I vibe coded a web extension for "Painless Preprint Posting": thenode.biologists.com/painless-pre...

submitted 2 days ago • 0 comments

The do’s and don’ts of scientific image editing Acceptable image-editing practices are partly a matter of common sense. But researchers say journals and funders could help scientists by standardizing policies. @sarareardon.bsky.social reports www.nature.com/articles/d41...

submitted 3 days ago • 4 comments

TIL you can add .txt to a biorxiv fulltext link and get plain text. Handy for pasting into LLMs, e.g., the new BindCraft revision www.biorxiv.org/content/10.1...

submitted 3 days ago • 1 comment

EB-t(h)ree

submitted 5 days ago • 1 comment

New posting! "Deprogramming academia", a riff on why I'm still feeling guilt about walking away from #academia, and why that might be. 👇 Hope you like it! #Alt-Ac totalinternalreflectionblog.com/2025/04/17/d...

submitted 15 days ago • 1 comment

Please take 5 min to give your feedback to @the-node.bsky.social Over the last 15 years it's become the go-to community blog for the dev bio and stem cell community What do you want from the Node over the next 15 years?

submitted 15 days ago • 0 comments

3D cell cultures better mimic real tissues than 2D—but how do we image them? This review explores 2D & 3D microscopy techniques for studying 3D cultures, highlighting strengths, limitations, and future innovation needs. #microscopy #bioengineering @naturemethods.bsky.social

submitted 15 days ago • 1 comment

Update on stable red FPs: mYonghong is out in @naturemethods.bsky.social, now renamed mScarlet3-H (logical as it's mScarlet3 with the M163H point mutation like mScarlet-H): www.nature.com/articles/s41... I guess mScarlet3-S2 (with added M66Q) will be out soon too, should be renamed mScarlet3-HQ 😁

submitted 15 days ago • 2 comments

As we turn 15, we want to collect feedback from you, our community, to ensure the Node is still relevant and useful. If you’ve ever visited the Node to read, write and interact with the #DevBio & #StemCell community, thank you! Please spare 5min to take our survey: www.surveymonkey.com/r/7QHYQCW

submitted 17 days ago • 0 comments

The latest AIC Call for Proposals is now open! Deadline is June 16, 2025. Come use @hhmijanelia.bsky.social imaging technology and expertise for FREE. Visit www.aicjanelia.org/apply for details. Before applying, contact us to schedule a technical consultation!

submitted 17 days ago • 0 comments

TIL: Null and zero are not equivalent in programming. Null is the absence of a value, while zero is a definite value. Null comes from Latin 'nullius' = 'ne'->"no" + 'ullus'->"any", so 'nullus' = "none" or literally "no anything." This is confusing in Norwegian, where null means zero.

submitted 17 days ago • 17 comments

Here's one of the incredible dataviz images that Ron Milo just showed at #EMBOclimateResilience, from the excellent Greenspan et al PNAS paper www.pnas.org/doi/epub/10....

submitted 17 days ago • 0 comments

My guidelines for exploratory data analysis

submitted 18 days ago • 3 comments

A review on Genetically-encoded temperature indicators for thermal biology by Takeharu Nagai and team: doi.org/10.2142/biop...

submitted 18 days ago • 0 comments

Experimenting with AI to revise a text. It does less well than I expected....

submitted 20 days ago • 4 comments

Did you know… It’s free to publish in Journal of Cell Science – there are no submission charges, page charges or colour fees. We also plant a tree for every peer-reviewed article we publish🌳 For details, visit our website: journals.biologists.com/jcs/pages/re...

submitted 23 days ago • 1 comment

Alpha-BET: Functional labeling of envelope glycoproteins with single domain antibodies for in-virus single molecule imaging by Sergio Padilla-Parra and team: www.biorxiv.org/content/10.1...

submitted 20 days ago • 0 comments

In my view, one major complication we have in "AI" is to focus on large language models, whereas actually I think the key technology steps are thing like attention networks - now a foundational part of large language models (LLMs).

submitted 21 days ago • 1 comment

Cool! Molecular and functional profiling of Gαi as an intracellular pH sensor www.nature.com/articles/s41...

submitted 21 days ago • 0 comments

yessss native penguins dataset in #rstats 4.5 ALSO the ability to load single functions from packages!

submitted 21 days ago • 3 comments

We've updated our preprint that reports on a "mTurquoise2-based glucose biosensor" with data of HeLa cells - the movie shows the effect of adding 5 mM of Glucose www.biorxiv.org/content/10.1...

submitted 21 days ago • 1 comment

There are very fancy microscopes, but most are overpriced commodities in an un-competitive industry that sells you 100 features you don't want for every one you do. And, unless you're a cell biologist or mouse-ologist, no one makes a microscope for the experiment you want to do.

submitted 39 days ago • 4 comments

Your yearly reminder to acknowledge the core facilities you use and their staff scientists in your papers. These scientists are a crucial part of the scientific ecosystem and to continue to exist they need tangible credit for their work. Plus their associated expertise adds credibility to your work.

submitted 22 days ago • 6 comments

Some positions open @poldresden.bsky.social take a look and apply to join us! physics-of-life.tu-dresden.de/career-educa...

submitted 22 days ago • 0 comments

www.nature.com/articles/d41...

submitted 22 days ago • 0 comments

Some "should be simple" features of a 3D viewer, like "focus" and positioning of a cube in the center of the view, can be notoriously complex (well, for me). Here is my current work in progress. I thought I could do all math in my head, but eventually had to add debugging geometry. #bigvolumebrowser

submitted 22 days ago • 3 comments

Quantifying Uncertainty in Phasor-Based Time-Domain Fluorescence Lifetime Imaging Microscopy by Liang Gao and team: www.biorxiv.org/content/10.1...

submitted 22 days ago • 0 comments

“Bluesky has won”. Please retweet… 😉

submitted 35 days ago • 3 comments