jorammooiweer.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

Reaching out to the #immunosky — would you want us to discuss your preprint? Tag us! We would be happy to provide feedback. 📝

submitted 2 days ago • 0 comments

PLOS has issued a statement on recent US Executive Orders and scientific integrity. We are determined to stand firmly behind our mission, our values and our principles, and against any attempt at censorship or undermining of the core principles of scientific inquiry. plos.io/3D4O8cH

submitted 4 days ago • 27 comments

Seems obvious, but apparently, no one has really dived into it like this(?)👇 🧬 Epigenetic variation in iPSCs staged is mostly tied to genetic variation, but as cells differentiate, this dilutes out quickly: Cell type matters more than genetics. #StemCells www.nature.com/articles/s41...

submitted 4 days ago • 0 comments

“The world’s a shit show, so why not put 💩 on a chip? Scientists created an iPSC-derived intestine-on-a-chip with fecal microbiota—uncovering epithelium-specific biomarkers & microbial factors linked to melanoma outcomes. Cutting-edge #OrganOnChip tech! #ImmunoSky #MedSky”

submitted 12 days ago • 2 comments

1/7: New paper alert! Excited to share our co-first author paper on Micro Immune Response On-chip (MIRO) a model that recreates the tumour-stroma interface for immunotherapy testing! @oriolmb.bsky.social and I wrote this thread to break it down for you. 👇🧵 Read more: www.nature.com/articles/s41...

submitted 15 days ago • 1 comment

Finally out! 🎉 Really happy to share my first co-author paper! It was wonderful to work with @aliperri.bsky.social , and huge thanks to @xaviertrepat.bsky.social for the opportunity to be part of this project. Grateful to the whole team for making this happen! www.nature.com/articles/s41...

submitted 18 days ago • 5 comments

NEW @preprintclub.bsky.social Journal Club of @biorxiv-immuno.bsky.social paper by @makris1.bsky.social @actonlab.bsky.social showing that loss of podoplanin in fibroblastic reticular cells results in decreased antibody levels and smaller germinal centres after immunization

submitted 19 days ago • 1 comment

IL27 enters the cytotoxicity party! #ImmunoSky #MedSky www.nature.com/articles/s41...

submitted 20 days ago • 0 comments

If any American immunologists want to write an op-ed for @immunolcellbiol.bsky.social on the impact of the new executive orders, please contact me

submitted 23 days ago • 1 comment

Incredible work! A study years in the making published in Nature. I’ve been waiting for this one. Engineered heart muscle patches from iPSC improve cardiac function in non-human primates…and are stable/show evidence for remuscularization in a human patient! Wow! ❤️ www.nature.com/articles/s41...

submitted 27 days ago • 0 comments

Its stories like this that makes me incredibly excited! A gut immune–epithelial circuit regulating tolerance to food: Goblet cell protein RELMβ disrupts tolerance by depleting microbiome-derived indoles needed for protective Tregs. #microbiome #immunity #ImmunoSky www.nature.com/articles/s41...

submitted 29 days ago • 0 comments

Great to see the European Organ-on-Chip Society represented on @bsky.app. Activity will ramp up in the coming period, but for now, please follow @euroocs.bsky.social #ooc #mps #microphysiological

submitted 29 days ago • 0 comments

Organoids in physiologically relevant culture systems (MPS/OoC) with realtime measurements of cellular responses. How far off are we of this becoming reality and also, of becoming the standard?

submitted 31 days ago • 0 comments

Very excited about this new work from our lab! Explainer thread coming soon @minetoota.bsky.social

submitted 32 days ago • 1 comment

Excellent perspective by @lisamjarvis.bsky.social @bloomberg.com on the deep freeze at NIH

submitted 32 days ago • 6 comments

A look behind the scenes at AAAS and scientific publishing through the eyes of the former EiC. Long thread, but worth reading every single post!

submitted 35 days ago • 0 comments

New paper alert 📢! (Cell) @cp-cell.bsky.social - How does immune responses to solid tumors vary by age and tumor characteristics in children?! www.cell.com/cell/fulltex... 🧵1/8

submitted 35 days ago • 3 comments

As a scientist, it’s impossible to continue to use a platform without meaningful moderation and where misinformation is allowed to spread unchecked. I’m happy to have moved my lab account here, and hope my colleagues do the same.

submitted 36 days ago • 1 comment

How do intestinal tissue regenerate. Very exciting new work form @priscaliberali.bsky.social shows how YAP1 and FOXA1 drive this process, ensuring stable tissue organization. And as always with stunning images and videos! 🔬🤩

submitted 41 days ago • 0 comments

A study across 316 patients and 21 cancers found the gene ETV7 shifts CD8+ T cells from memory states to exhaustion, lowering their ability to fight tumors and viruses. www.nature.com/articles/s43...

submitted 43 days ago • 0 comments

TG2 (Transglutaminase 2) is responsible for the deamidation of gluten peptides, making them immunogenic antigens in the context of Celiac Disease - But what other functions does TG2 have?! 👇 TG2 drives epigenetic histone monoaminylation, regulating neural rhythmicity 🧠! #Celiac

submitted 43 days ago • 2 comments

We proudly present our preprint (i.e. not peer-reviewed yet!) on the gut microbiome of treated coeliac disease (tCeD) patients: https://www.biorxiv.org/content/10.1101/2024.03.08.584098v2 w/ Hanna Simpson, @irisjonkers.bsky.social, Sebo Withoff and many others. An explanatory thread 🧵 (1/15)

submitted 49 days ago • 2 comments

An optimized protocol for XYZ… Isn’t protocol optimization just a fancy way of saying, ‘Hey, it works!’? Let’s be real—‘good enough’ works, and getting it fully optimized to ‘perfect’ is hard: so many factors to test… There’s always room for improvement, but deadlines don’t care.

submitted 50 days ago • 0 comments

Time to log off for the holidays with a timelapse: Intestinal organoid trying to resist the attack from CD8 T cells. Happy holidays! 🎄🧑‍🎄 #ImmunoSky

submitted 62 days ago • 1 comment

What are lumens and how do forces control tissue form and fate through lumen size? Join me, @dhirajindana.bsky.social, in this short thread to explore this question through some fascinating papers.

submitted 67 days ago • 2 comments

Ever wondered how gut microbes control immune responses at extra-intestinal locations? Here #theonlylabever reports how a gut protozoan commensal shapes pulmonary immunity to exacerbate asthma and limit the dissemination of mycobacteria. @cellpress.bsky.social ⬇️(1/x) www.cell.com/cell/fulltex...

submitted 68 days ago • 10 comments

We've just joined Bluesky 🎉 Follow us for research, news, comment and opinion from Nature journal 🧪

submitted 68 days ago • 36 comments

Arrived. Excited for a 2-day Netherlands Organ-on-Chip Consortium gathering at the @hubrechtinstitute.bsky.social #Organoids #OrganOnChip #NOCI

submitted 70 days ago • 0 comments

1/ We are excited to share our new paper in @jexpmed.bsky.social about humans with autosomal dominant IFNAR1 deficiency (doi.org/10.1084/jem....).

submitted 70 days ago • 7 comments

How does the immune system make "decisions" at mucosal barriers? My new perspective explores how seeing strategic cell interactions through the lens of game theory could reveal fresh insights into mucosal immune homeostasis and disease. 🧵 1/7 www.sciencedirect.com/science/arti...

submitted 72 days ago • 4 comments

Today we report that an engineered skin bacterium, swabbed gently on the head of a mouse, can unleash a potent antibody response against a pathogen. Could lead to topical vaccines that are applied in a cream. @djenetbousbaine.bsky.social led the charge... @natureportfolio.bsky.social 1/55

submitted 76 days ago • 24 comments

This platform keeps getting better and better! 😍🦋 The @preprintclub.bsky.social joined the bright side. #immunosky Share and follow for inter-institutional, trainee community reviews of preprint articles. #preprints #openacess www.preprintclub.com

submitted 77 days ago • 2 comments

From GWAS variants⚡️to key-genes🧬: Downstreamer is your tool! This tool developed by (former) colleagues @patrickdeelen.bsky.social, @anniquec.bsky.social and Olivier Bakker incorporates GWAS Variants and tissue specific co-regulation to identify key genes for common diseases 👇Explainer

submitted 77 days ago • 0 comments

Downstreamer is now available: www.nature.com/articles/s41... We used 57 tissue specific gene expression networks to identify key genes of common diseases. 78% of these key genes are located outside of GWAS loci. 1/4

submitted 83 days ago • 1 comment

Speaker line up for #EMBOTissueImmunity to take place in Basel 🇨🇭 26-29 August 2025. Come join @maurogaya.bsky.social and I for some fantastic #immunology along the Rhine! Please share this invitation - we hope you will join us. Registrations will be open soon.

submitted 77 days ago • 3 comments