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joseph-kim.bsky.social
Postdoctoral Scientist in Aashish Manglik’s lab at UCSF: Biochemistry, cryo-EM, and pharmacology of GPCRs and transporters PhD from University of Wisconsin-Madison: CLEM and Cryo-ET on neuronal cells Triathlons, desserts, books, museums and video games
10 posts 335 followers 574 following
Getting Started

It's definitely a part of my workflow now, cause so far it's been one of the most impactful non-3D reconstruction data processing changes that I can make.

Hi everyone! I am thrilled to share my first publication while in @amanglik.bsky.social's lab! I performed the biochemistry and structural work for compounds that had antagonistic opioid receptor polypharmacology. Congratulations to everyone involved in this project! www.biorxiv.org/content/10.1...

Congratulations José! Always a pleasure to work with you in the Manglik lab at USCF! @amanglik.bsky.social

Well done Matt! DMS is such a powerful way to study GPCRs

Groundbreaking work by @matthewkhoward.bsky.social and Nicholas Hoppe (not on bsky?) from the @willowcoyote.bsky.social @amanglik.bsky.social labs. Mapping function to structure with deep mutational scanning to resolve the mechanisms of pH sensing GPCRs www.sciencedirect.com/science/arti...

Check out the magnificent #baculovirus structure! The unique virion architecture and structural atlas of hallmark proteins place baculo-like viruses into a separate new realm. Many insights into baculo biology and evolution. Collab with the group of Fasséli Coulibaly. www.science.org/doi/10.1126/...

Take a look at my personal perspective on the past, present, and future of in situ structural biology with cryo-ET+ While initially skeptical about the genre, I found it fun to write and hopefully, you can enjoy my experiences and some thoughts. Nice weekend y'all www.cambridge.org/core/journal...

Our newest Interviews with Authors episode is online! We chat with Daija Bobe, Jessalyn Miller and Ed Eng (@edwardteng.bsky.social) from the New York Structural Biology Center about their paper "Multi-species #cryoEM calibration and workflow verification standard". www.youtube.com/watch?v=DB83...